Browse our WASF1 Proteins (WASF1)

The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

• WAS protein family member 1 S homeolog (wasf1.S)
• SCAR family protein (AT2G34150)
• WAS protein family member 1 (wasf1)
• WAS protein family member 1 (WASF1)
• WAS protein family, member 1 (Wasf1)

• AI195380 protein
• AI838537 protein
• ATRANGAP2 protein
• ATSCAR1 protein
• Scar protein
• Show all synonym aliases
• SCAR1 protein
• T14G11.27 protein
• T14G11_27 protein
• WAVE protein
• WAVE-1 protein
• WAVE1 protein
• WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY VERPROLIN HOMOLOGOUS PROTEIN 1 protein

WASP family protein member 1 , homology of dictyostelium scar 1 , protein WAVE-1 , verprolin homology domain-containing protein 1 , wiskott-Aldrich syndrome protein family member 1 , WASP family 1