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anti-Human COL1A1 Antibodies:
anti-Mouse (Murine) COL1A1 Antibodies:
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Human Polyclonal COL1A1 Primary Antibody for ICC, IHC (fro) - ABIN3043986
Wang, Fan, Li, Wang, Gao, Yang: Oxidative stress promotes myocardial fibrosis by upregulating KCa3.1 channel expression in AGT-REN double transgenic hypertensive mice. in Pflügers Archiv : European journal of physiology 2017
Show all 34 Pubmed References
Human Polyclonal COL1A1 Primary Antibody for ICC, IHC (fro) - ABIN5518708
Chen, Wan, Xia, Guo, Wang, Liu, Li: Promoted regeneration of mature blood vessels by electrospun fibers with loaded multiple pDNA-calcium phosphate nanoparticles. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fu?r Pharmazeutische Verfahrenstechnik e.V 2013
Show all 32 Pubmed References
Human Polyclonal COL1A1 Primary Antibody for ELISA, WB - ABIN514510
Park, Kim, Kim, Oh: Antioxidant effects of the sarsaparilla via scavenging of reactive oxygen species and induction of antioxidant enzymes in human dermal fibroblasts. in Environmental toxicology and pharmacology 2014
DNMT1 (show DNMT1 Antibodies) was downregulated in the Lung Cancer group and its expression was further reduced in the presence of increasing malignant burden as indicated by the endobronchial findings further suggesting an Lung Cancer-specific signature.
our results indicated that COL1A1 promotes tumor metastasis, and that its inhibition may suppress CRC (show CALR Antibodies) cell migration. In addition, the role of COL1A1 in CRC (show CALR Antibodies) metastasis seems to be associated with the regulation of the WNT (show WNT2 Antibodies)/PCP (show PRCP Antibodies) pathway.
miR378b represses the mRNA expression levels of COL1A1 via interference with SIRT6 (show SIRT6 Antibodies) in human dermal fibroblasts.
Exogenous proline stimulates type I collagen and HIF-1alpha (show HIF1A Antibodies) expression and the process is attenuated by glutamine (show GFPT1 Antibodies) in human skin fibroblasts.
the efficacy of pamidronate treatment does not seem to be related to the genotype of type I collagen in patients with osteogenesis imperfecta (show COL1A2 Antibodies).
MiR (show MLXIP Antibodies)-133a-3p could inhibit the proliferation and migration of oral squamous cell carcinoma cells through directly targeting COL1A1 and reducing its expression.
COL1A1 gene mutation is associated with osteogenesis imperfecta (show COL1A2 Antibodies).
Elevation of serum alpha1(I) collagen DNA levels in scleroderma patients may be useful as the diagnostic marker, reflecting the presence of vasculopathy.
study showed that GG homozygotes were underrepresented in the ACL (show ACLY Antibodies)-rupture group compared with the control group, which suggests an association with reduced risk of anterior cruciate ligament injury
Review/Meta-analysis: possible relationship between GG genotype of COL1A1 +1245G/T polymorphism and osteoporosis risk in post-menopausal women.
findings suggest that deficiencies of leucine and isoleucine reduce type I and III tropocollagen syntheses in skin by suppressing the action of mTOR (show FRAP1 Antibodies)
Our studies demonstrate that a collagen-I-dense ECM (show MMRN1 Antibodies) can potently alter hormonal signals to drive the progression of ERalpha (show ESR1 Antibodies) + breast cancer, increasing intravasation and pulmonary metastases.
a surface population of Hsp90 (show HSP90 Antibodies) extracellularly binds TGFbetaRI and this complex behaves as an active participant in collagen production in TGFbeta (show TGFB1 Antibodies)-activated fibroblasts.
osthole could inhibit the collagen I and III expressions and their ratio in CFs treated with TGF-beta1 (show TGFB1 Antibodies) via Smad (show SMAD1 Antibodies) signaling pathway, which might be one of its anti-fibrotic action mechanisms.
Gremlin1 accelerates hepatic stellate cell activation through upregulation of TGF-B1, alpha-SMA (show SMN1 Antibodies), and COL1a1 expression in a liver fibrosis disease model.
Type I collagen was highly expressed in the spinal cord during the scar-forming phase and induced astrocytic scar formation via the integrin-N-cadherin (show CDH2 Antibodies) pathway.
collagen-I-mediated inhibition of proplatelet formation is specifically controlled by GPVI (show GP6 Antibodies).
miR (show MLXIP Antibodies)-29b can reduce collagen biosynthesis during skin wound healing likely via post-transcriptional inhibition of HSP47 (show SERPINH1 Antibodies) expression.
Col1a1Jrt/+ mutant mice produce craniofacial and dental defects consistent with osteogenesis imperfecta (show COL1A2 Antibodies) and Ehlers-Danlos syndrome
the rate of collagen I degradation was increased in Poldip2 (show POLDIP2 Antibodies)(+/-) vs. Poldip2 (show POLDIP2 Antibodies)(+/+) MASMs. Conversely, activation of the PI3K/Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway, involved in regulation of protein synthesis, was significantly elevated in Poldip2 (show POLDIP2 Antibodies)(+/-) MASMs as was beta1-integrin expression.
These observations support a signaling network among JNKs, Smads, Snail1 (show SNAI1 Antibodies), and cortactin (show CTTN Antibodies) to regulate the invasion of MDA-MB-231 cells embedded in 3D collagen I, which may be targeted during screening of anti-invasion reagents.
Data show that biglycan (show BGN Antibodies), collagen type I, collagen type II, decorin (show DCN Antibodies), and versican (show Vcan Antibodies) were significantly affected by vibration duration, frequency, and amplitude.
specific ADAMTS-2 (show Adamts2 Antibodies) domains cleave the aminopropeptide of fibrillar procollagens types I-III and V
In advanced stage granulomas in Mycobacterium bovis-infected cattle, there was an increase in the expression of type I procollagen (show COL1A2 Antibodies)
These results demonstrate a novel and important functional role of the DDR2 (show DDR2 Antibodies) extracellular domain that may contribute to collagen regulation via modulation of fibrillogenesis.
Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
A molecular model of collagen hydration is used to validate centrifugal dehydration force (CDF (show CTNNA2 Antibodies)) and re-hydration isotherm (RHI) methods to measure and characterize hydration compartments on bovine tendon.
ven though in adult bone, skin and scales equal amounts of a1(col1a1a) a2(col1a2 (show COL1A2 Antibodies)) and a3(col1a2 (show COL1A2 Antibodies))chains are present, the presented data suggest a tissue-specific stoichiometry and/or post-translational modification status for collagen type I
heterozygous chihuahua fish have phenotypic similarities to human osteogenesis imperfecta; mapping and molecular characterization of the chihuahua mutation indicates that the defect resides in the gene encoding the collagen I(alpha1) chain
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
alpha-1 type I collagen
, collagen alpha 1 chain type I
, collagen alpha-1(I) chain
, collagen alpha-1(I) chain preproprotein
, collagen of skin, tendon and bone, alpha-1 chain
, pro-alpha-1 collagen type 1
, alpha-1 type 1 collagen
, procollagen, type I, alpha 1
, collagen, type 1, alpha 1
, procollagen type I, alpha 1
, procollagen, type 1, alpha 1
, collagen, type I, alpha 1
, type I collagen alpha 1 chain
, type I collagen alpha1
, type I collagen pre-pro-alpha1(I) chain
, alpha 1 type I collagen
, collagen, type I, alpha 2
, collagen type I alpha 1
, prepro-alpha-1 collagen type I
, procollagen alpha 1 (I)
, collagen 1a1
, pro-alpha-1 type 1 collagen
, alpha-1 collagen (I)
, collagen alpha-1 chain
, collagen, type I, alpha 1b
, collagen, type I, alpha 3