Browse our KCNE1 Proteins (KCNE1)

Xenopus laevis Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) interaction partners

1. TNIK (Traf2 and Nck-interacting kinase (show TNIK Proteins)) and MINK (Misshapen/NIKs-related kinase) MAP4K signalling kinases are integral components of both canonical and non-canonical pathways in Xenopus.

2. KCNE1/KCNQ1 (show KCNQ1 Proteins) was expressed in Xenopus oocytes with and without beta-catenin (show CTNNB1 Proteins). Confocal microscopy revealed that beta-catenin (show CTNNB1 Proteins) enhanced the KCNE1/KCNQ1 (show KCNQ1 Proteins) protein abundance in the cell membrane.

3. PIP(2) has a role in KCNE1 modulation of I(Ks) channels that may represent a common mechanism of auxiliary subunit modulation of many ion channels

4. characterize a new component of the early bioelectrical circuit: the potassium channel (show KCNAB2 Proteins) KCNQ1 (show KCNQ1 Proteins) and its accessory subunit KCNE1

5. phenylboronic acid (PBA) activates KCNQ1 (show KCNQ1 Proteins)/KCNE1 complexes

Human Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) interaction partners

1. All the protein systems generated through these processes were refined by long Molecular Dynamics simulations. The refined models were analyzed extensively to infer data about the interaction of KCNQ1 (show KCNQ1 Proteins) channel with its accessory KCNE1 beta subunits.

2. In lesion samples collected from children with cardiac insufficiency, for Mink-S27 (show RPS27 Proteins), we detected significant difference in AA, CC genotype frequency and allele frequency between the observation group and the control group

3. SUMOylation of KCNQ1 (show KCNQ1 Proteins) is KCNE1 dependent and determines the native attributes of cardiac IKs in vivo.

4. Equine KV7.1 (show KCNQ1 Proteins)/KCNE1 expressed in CHO (show COL11A1 Proteins)-K1 cells exhibited electrophysiological properties that are overall similar to the human orthologs; however, a slower deactivation was found which could result in more open channels at fast rates.

5. The KCNE1 (rs1805127) appears to an independent risk factor for AF in the Uygur population. And the KCNE4 (show KCNE4 Proteins) (rs12621643) was an independent risk factor for AF among both Uygurs and Hans.

6. Western blotting analysis combined with these pharmacological data suggest that long-term insulin (show INS Proteins) treatment augments KCNQ1 (show KCNQ1 Proteins)/KCNE1 currents by increasing KCNE1 protein expression.

7. KCNQ1/KCNE1 channel does not require phosphatidylinositol-4,5-bisphosphate (PIP2) or phosphatidylinositol-4-phosphate for anterograde trafficking, but is heavily reliant on PIP2 for channel function once at the plasma membrane.

8. The genetic variant rs426496 in AQP2 (show AQP2 Proteins); rs591810 in AQP3 (show AQP3 Proteins) and rs1805127, rs1805128, and rs17173510, in KCNE1 were found in patients with Meniere's disease

9. Meta-analysis suggests that the G38S polymorphism in the KCNE1 gene can significantly increase the risk of atrial fibrillation in both Chinese and white individuals.

10. Sphingomyelin synthase 1 (show SGMS1 Proteins) positively regulates KCNQ1 (show KCNQ1 Proteins)/KCNE1 channel density in a protein kinase D (show PRKD1 Proteins)-dependent manner.

Rabbit Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) interaction partners

1. miR-1 by anti-miR-1 inhibitor oligonucleotides alleviated the downregulation of KCNE1 and KCNB2 (show KCNB2 Proteins), the shortening of AERP, and the increase in the IKs

Cow (Bovine) Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) interaction partners

1. The localization of KCNE1 in the RPE (show RPE Proteins) basal membrane, where KCNQ5 (show KCNQ5 Proteins) was previously found to be present, suggests that this beta-subunit (show POLG Proteins) may contribute to M-type K(+) channels in this membrane.

Mouse (Murine) Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1) interaction partners

1. SUMOylation of KCNQ1 (show KCNQ1 Proteins) is KCNE1 dependent and determines the native attributes of cardiac IKs in vivo.

2. The electrophysiological effects of BACE1 (show BACE Proteins) on KCNQ1 (show KCNQ1 Proteins) reported here were independent of its enzymatic activity.

3. KCNE1 and KCNE3: The yin and yang of voltage-gated K(+) channel (show KCND3 Proteins) regulation

4. KCNE1 and KCNE2 (show KCNE2 Proteins), auxiliary subunits of voltage-gated potassium channels, undergo sequential cleavage mediated by either alpha-secretase and presenilin(PS)/gamma-secretase or BACE1 (show BACE Proteins) and PS/gamma-secretase in cells.

5. In clearance studies the KCNE1 knockout mice had an increased fractional excretion of Na+, Cl-, HCO3(-) and water.

6. This study confirmed that KCNE1 channels are necessary for K+ secretion in developmental Saccule and Utricle in mice.

7. both the voltage-dependence and kinetics of gating were found to depend on the relative densities of KCNQ1 (show KCNQ1 Proteins) and KCNE1, suggesting the heart rhythm may be regulated by the relative expression of the auxiliary subunit

8. Findings directly implicate triggered electrical activity and spatial and temporal re-entrant mechanisms in the arrhythmogenesis observed in KCNE1 (-/-) hearts.

9. intestinal Cl(-) secretion is independent from KCNE1 but requires KCNQ1 (show KCNQ1 Proteins) and in mouse pancreatic acini KCNQ1 (show KCNQ1 Proteins) probably co-assembled with KCNE1 leads to a voltage-dependent K(+) current that might be of importance for electrolyte and enzyme secretion.

10. the spatial expression of minK-lacZ (show GLB1 Proteins) in the adult mouse heart has been shown, for the larger part, to be coincident with the conduction tissues