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SLIT2 Products

(Slit Homolog 2 (Drosophila) (SLIT2))
acts as a ligand for glypican-1, a heparan sulfate proteoglycan\; may play a role in neurogenesis and midline development [RGD, Feb 2006].

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Featured SLIT2 Categories

SLIT2 Antibodies

High quality antibodies with extensive validation data.

SLIT2 ELISA Kits

Reliable ELISA kits for a wide range of species.

SLIT2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SLIT2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7438007
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7445819
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7239467
Quantity 200 μL
Datasheet Datasheet

Recommended SLIT2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
Cat. No. ABIN6959507
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970242
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970240
Quantity 96 tests
Datasheet Datasheet

Recommended SLIT2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320564
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095523
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3137448
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SLIT2 products

Tumelty, Higginson-Scott, Fan, Bajaj, Knowlton, Shamashkin, Coyle, Lu, Berasi: "Identification of direct negative cross-talk between the SLIT2 and bone morphogenetic protein-Gremlin signaling pathways." in: The Journal of biological chemistry, Vol. 293, Issue 9, pp. 3039-3055, (2019) (PubMed).

Zeng, Wu, Cao, Yuan, Zhang, Zhang, Hasegawa, Friedman, Guo: "Slit2-Robo2 signaling modulates the fibrogenic activity and migration of hepatic stellate cells." in: Life sciences, Vol. 203, pp. 39-47, (2018) (PubMed).

Chatziharalambous, Lygirou, Latosinska, Stravodimos, Vlahou, Jankowski, Zoidakis: "Analytical Performance of ELISA Assays in Urine: One More Bottleneck towards Biomarker Validation and Clinical Implementation." in: PLoS ONE, Vol. 11, Issue 2, pp. e0149471, (2016) (PubMed).

Chang, Lan, Li, Ji, Zheng, Gou, Ou, Wu, Qi, Zhang, Li, Gu, Wen, Cao, Qiao, Ding, Wang: "Activation of Slit2-Robo1 signaling promotes liver fibrosis." in: Journal of hepatology, (2015) (PubMed).

Cai, Xue, Li, Hu, Wang, Liu, Li, Liu: "Roundabout4 suppresses glioma-induced endothelial cell proliferation, migration and tube formation in vitro by inhibiting VEGR2-mediated PI3K/AKT and FAK signaling pathways." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 35, Issue 5, pp. 1689-705, (2015) (PubMed).

Beggs, Jones, Shepherd, Arnaout, Finlayson, Abulafi, Morton, Matthews, Hodgson, Tomlinson: "Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation." in: PLoS genetics, Vol. 9, Issue 5, pp. e1003488, (2013) (PubMed).

Dickinson, Fegan, Ren, Hillier, Duncan: "Glucocorticoid regulation of SLIT/ROBO tumour suppressor genes in the ovarian surface epithelium and ovarian cancer cells." in: PLoS ONE, Vol. 6, Issue 11, pp. e27792, (2012) (PubMed).

Bauer, Dowejko, Bosserhoff, Reichert, Bauer: "Slit-2 facilitates interaction of P-cadherin with Robo-3 and inhibits cell migration in an oral squamous cell carcinoma cell line." in: Carcinogenesis, Vol. 32, Issue 6, pp. 935-43, (2011) (PubMed).

Zhou, Yu, Xie, Huang, Xu, Li: "The role of SLIT-ROBO signaling in proliferative diabetic retinopathy and retinal pigment epithelial cells." in: Molecular vision, Vol. 17, pp. 1526-36, (2011) (PubMed).

Brantley-Sieders, Dunaway, Rao, Short, Hwang, Gao, Li, Jiang, Shyr, Wu, Chen: "Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium." in: Cancer research, Vol. 71, Issue 3, pp. 976-87, (2011) (PubMed).

Synonyms and alternative names related to SLIT2

slit guidance ligand 2 (SLIT2), slit homolog 2 (Drosophila) (Slit2), slit homolog 2 (Drosophila) (slit2), slit guidance ligand 2 (Slit2), slit guidance ligand 2 S homeolog (slit2.S), Drad-1, E030015M03Rik, E130320P19Rik, mKIAA4141, SLIL3, Slil3, slil3, Slit, Slit-2, slit-2, SLIT2, slit2-a

Protein level used designations for SLIT2

  • slit homolog 2 protein
  • downregulated during adipocyte differentiation-1
  • neurogenic extracellular slit protein
  • slit-2
  • slit homolog 2 (Drosophila)
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