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TET1 Proteins

(Tet Methylcytosine Dioxygenase 1 (TET1))

Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5- hydroxymethylcytosine (5hmC). Might initiate a process leading to cytosine demethylation through deamination into 5- hydroxymethyluracil (5hmU) and subsequent replacement by unmethylated cytosine by the base excision repair system. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. Preferentially binds to CpG-rich sequences at promoters of both transcriptionally active and polycomb-repressed genes. By controlling the levels of 5mC and 5hmC at gene promoters, it may regulate the gene expression silencing induced by cytosine methylation. May have a dual function by also repressing the expression of a subset of genes through recruitment of transcriptional repressors to promoters. Involved in the balance between pluripotency and lineage commitment of cells it plays a role in embryonic stem cells maintenance and inner cell mass cell specification.

recommended

TET1 Protein (AA 2038-2136) (GST tag) (ABIN1322493)

TET1 Origin: Human Host: Wheat germ Recombinant WB, AP, AA, ELISA

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recommended

TET1 Protein (GST tag) (ABIN6700691)

TET1 Origin: Human Host: Insect cells (Sf9) Recombinant >90% WB

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TET1 Proteins by Origin

Find TET1 Proteins for a variety of species such as anti-Human TET1. The species listed below are among those available. Click on a link to go to the corresponding products.

TET1 Proteins by Source

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TET1 Proteins by Protein Type

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TET1 Proteins by Application

Find TET1 Proteins validated for a specific application such as WB, AP, AA, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular TET1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

TET1 Protein (AA 2038-2136) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1322493

Quantity 10 μg

Datasheet Datasheet

TET1 Protein (GST tag)

Reactivity Human

Source Insect cells (Sf9)

Validations

Cat. No. ABIN6700691

Quantity 20 μg

Datasheet Datasheet

Aliases for TET1 Proteins

tet methylcytosine dioxygenase 1 (TET1) Proteins
tet methylcytosine dioxygenase 1 (Tet1) Proteins
solute carrier family 25 member 16 (SLC25A16) Proteins
2510010B09Rik Proteins
AA517754 Proteins
bA119F7.1 Proteins
BB001228 Proteins
CXXC6 Proteins
Cxxc6 Proteins
D10Ertd17e Proteins
LCX Proteins
mKIAA1676 Proteins

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TET1 Proteins by Origin

TET1 Proteins by Source

TET1 Proteins by Protein Type

TET1 Proteins by Application

Popular TET1 Proteins

Aliases for TET1 Proteins

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