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Human Polyclonal UGT2B15 Primary Antibody for FACS, IF - ABIN656309
Yong, Schwartz, Atkinson, Makar, Thomas, Newton, Aiello Bowles, Holt, Leisenring, Lampe: Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010
Show all 3 Pubmed References
High UGT2B15 expression is associated with the pathogenesis of gastric cancer.
This study showed that UGT2B7 (show UGT2B7 Antibodies) and UGT2B15 3'-UTRs contain miRNA response elements for multiple miRNAs that may contribute to variable drug glucuronidation.
Results found no significant increased risk for benign prostatic hyperplasia (BPH (show GLI3 Antibodies)) in men with low activity genotype at D85Y, but found rather, a significant association between UGT2B15 D85Y and BPH (show GLI3 Antibodies) risk when it is in combination with the UGT2B17 (show UGT2B17 Antibodies) copy number variation.
Our findings highlight the influence of UGTT1A4 haplotypes on tamoxifen disposition in Asian breast cancer patients, while genetic variants in UGT2B7 (show UGT2B7 Antibodies) and UGT2B15 appear to be of minor importance.
the UGT2B15 and UGT2B17 (show UGT2B17 Antibodies) enzymes are transcriptionally regulated by sex hormone signaling in ERalpha (show ESR1 Antibodies)+ breast cancer cells and are highly expressed in a subset of primary breast cancers.
UGT2B15 genotype contributes to postoperative anxiety reduction after lorazepam premedication.
Report frequency of UGT2B15 genetic polymorphisms in Pakistani population and genotype/phenotype correlation for glucuronidation of paracetamol.
CYP3A4 (show CYP3A4 Antibodies), CYP3A7 (show CYP3A7 Antibodies), UGT2B11 (show UGT2B4 Antibodies) and UGT2B15 genes are significantly downregulated in melanosis coli.
This descriptive study examines correlations between concentrations of tamoxifen's glucuronide metabolites and genotypes UGT1A4 (show UGT1A4 Antibodies), UGT2B7 (show UGT2B7 Antibodies), UGT2B15 and UGT2B17 (show UGT2B17 Antibodies) in 132 patients with estrogen receptor (show ESR1 Antibodies)-positive breast cancer under treatment with tamoxifen
miR (show MLXIP Antibodies)-376c is inversely linked to UGT2B15 and UGT2B17 (show UGT2B17 Antibodies) expression in high-grade prostate cancer and metastasis.UGT2B15 and UGT2B17 (show UGT2B17 Antibodies) genes are direct targets of miR (show MLXIP Antibodies)-376c and thus may influence steroid metabolism during prostate cancer progression.
This gene encodes a member of the UDP-glycosyltransferase (UDPGT) family. The UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein displays activity towards several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens.
UDP glycosyltransferase 2 family, polypeptide B28
, UDP glucuronosyltransferase 2 family, polypeptide B15
, UDP glycosyltransferase 2B15
, UDP-glucuronosyltransferase 2B15
, UDP-glucuronosyltransferase 2B8
, UDP-glucuronosyltransferase UGT2B15
, UDP-glucuronyltransferase, family 2, beta-15
, UDPGT 2B15