Browse our Protoporphyrinogen Oxidase Proteins (PPOX)

Full name:: Protoporphyrinogen Oxidase Proteins (PPOX)

On www.antibodies-online.com are 9 Protoporphyrinogen Oxidase (PPOX) Proteins from 5 different suppliers available. Additionally we are shipping Protoporphyrinogen Oxidase Antibodies (61) and Protoporphyrinogen Oxidase Kits (23) and many more products for this protein. A total of 98 Protoporphyrinogen Oxidase products are currently listed.

Synonyms:: BcDNA:LD41392, CG5796, Dmel\\CG5796, ESTS:9F2T, hemG, HEMG1, Ppo, PPO1, PROTOPORPHYRINOGEN OXIDASE, TC0121, V290M, VP, zgc:123252

list all proteins	Gene Name	GeneID	UniProt
	PPOX	5498	P50336
	PPOX	19044	P51175
	PPOX	289219
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Protoporphyrinogen Oxidase Proteins (PPOX) by Origin

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Human Protoporphyrinogen Oxidase (PPOX) interaction partners

the regulation of PPOX (show OX Proteins) gene expression can also occur through a post-transcriptional modulation of the amount of gene product and this modulation can be mediated by 5' untranslated exon 1.
GAPDH (show GAPDH Proteins) and protoporphyrinogen oxidase were shown to have higher expression in faster growing cell lines and primary tumors. Pharmacologic inhibition of GAPDH (show GAPDH Proteins) or PPOX (show OX Proteins) reduced the growth of colon cancer cells in vitro
Variegate porphyria is the result of decreased protoporphyrinogen oxidase activity. Diet supplementation with vitamins E and C restores PPOX (show OX Proteins) gene expression in lymphocytes of variegate porphyria patients.
in the hepatic cancer tissue of two acute porphyria patients, somatic second-hit mutations result in nearly complete inactivation of PPOX (show OX Proteins) and HMBS (show HMBS Proteins)
The c.851G>T and the c.1013C>G of PPOX (show OX Proteins) gene were found in two and four unrelated families respectively. 1 experienced only photosensitivity, 1 only neurological symptoms and the 2 both clinical manifestations.
The mutation 1082-1083insC(1 base pair insertion at position 1082) in exon 10 of the PPOX (show OX Proteins) gene was prevalent in the Swiss population.
findings emphasize the usefulness of MLPA analysis as a complement to PPOX (show OX Proteins) gene sequencing analysis for comprehensive genetic diagnostics in patients with variegate prophyria
Information required for targeting to the mitochondria is contained within the first 250 amino acid residues of human PPOX (show OX Proteins).
Modulation of penetrance by the wild-type allele in dominantly inherited erythrohepatic and acute hepatic porphyrias was studied using PPOX (show OX Proteins).
Protoporphyrinogen oxidase targeting mechanism to the mitochondrion.

Mouse (Murine) Protoporphyrinogen Oxidase (PPOX) interaction partners

Arabidopsis thaliana Protoporphyrinogen Oxidase (PPOX) interaction partners

The tetrapyrrole biosynthetic enzyme PPO1 is required for plastid RNA editing.

Cow (Bovine) Protoporphyrinogen Oxidase (PPOX) interaction partners

determined significant differences in the proteomes of freshly ingested down boli corresponding to the presence or absence of active PPO. These results show that in the presence of PPO the forage protein is less amenable to proteolysis and provide the novel information that the protected proteins are putatively chloroplastically located.

Protoporphyrinogen Oxidase (PPOX) Protein Profile

Protein Summary

This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Alternative names and synonyms associated with Protoporphyrinogen Oxidase (PPOX)

protoporphyrinogen oxidase (PPOX)
protoporphyrinogen oxidase (Ppox)
Protoporphyrinogen oxidase (Ppox)
protoporphyrinogen oxidase (ppox)
Flavin containing amine oxidoreductase family (PPOX)
protoporphyrinogen oxidase (hemY)
protoporphyrinogen oxidase (TC_RS00645)
protoporphyrinogen oxidase (Mrub_1406)
protoporphyrinogen oxidase (Mesil_2992)
protoporphyrinogen oxidase (Trad_0583)
protoporphyrinogen oxidase (Calni_0746)
protoporphyrinogen oxidase (Ocepr_1049)
protoporphyrinogen oxidase (Tmar_0766)
protoporphyrinogen oxidase (Intca_1907)
protoporphyrinogen oxidase (Despr_0642)
protoporphyrinogen oxidase (Plabr_2407)
protoporphyrinogen oxidase (Deipr_2130)
protoporphyrinogen oxidase (Hipma_0622)
polyphenol oxidase, chloroplastic (LOC110782963)

BcDNA:LD41392 protein
CG5796 protein
Dmel\\CG5796 protein
ESTS:9F2T protein
hemG protein
HEMG1 protein
Ppo protein
PPO1 protein
PROTOPORPHYRINOGEN OXIDASE protein
TC0121 protein
V290M protein
VP protein
zgc:123252 protein

Protein level used designations for PPOX

protoporhyrinogen oxidase , protoporphyrinogen oxidase , CG5796-PA , Ppox-PA , protoporphyrinogen-oxidase , mno , montalcino , ppo , Catechol oxidase , polyphenol oxidase, chloroplastic

GENE ID	SPECIES
5498	Homo sapiens
19044	Mus musculus
42939	Drosophila melanogaster
289219	Rattus norvegicus
664750	Danio rerio
827991	Arabidopsis thaliana
887711	Mycobacterium tuberculosis H37Rv
894184	Bacillus halodurans C-125
910131	Mycobacterium leprae TN
1017310	Oceanobacillus iheyensis HTE831
1121814	Staphylococcus aureus subsp. aureus Mu50
1245655	Chlamydia muridarum Nigg
2860707	Staphylococcus aureus subsp. aureus MRSA252
3204574	Bacillus clausii KSM-K16
3958489	Chlamydophila felis Fe/C-56
5331016	Staphylococcus aureus subsp. aureus str. Newman
5560658	Staphylococcus aureus subsp. aureus Mu3
6226299	Mycobacterium marinum M
7324674	Mycobacterium leprae Br4923
7550597	Staphylococcus carnosus subsp. carnosus TM300
8767366	Bacillus pseudofirmus OF4
8879503	Meiothermus ruber DSM 1279
9252515	Meiothermus silvanus DSM 9946
9279560	Truepera radiovictrix DSM 17093
10008757	Calditerrivibrio nitroreducens DSM 19672
10015901	Oceanithermus profundus DSM 14977
10081140	Thermaerobacter marianensis DSM 12885
10084727	Intrasporangium calvum DSM 43043
10173352	Desulfobulbus propionicus DSM 2032
10239818	Planctomyces brasiliensis DSM 5305
10265450	Deinococcus proteolyticus MRP
10391952	Hippea maritima DSM 10411
478980	Canis lupus familiaris
515770	Bos taurus
100153636	Sus scrofa
100340158	Oryctolagus cuniculus
110782963	Spinacia oleracea
100735630	Cavia porcellus
100066168	Equus caballus

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