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RABGEF1 mediates recycling endosome fusion with GAS-containing autophagosome-like vacuoles through the STX6-VAMP3-VTI1B complex; SNAREs are involved in autophagosome formation in response to bacterial infection
Potent inhibition of human cytomegalovirus has been reported by modulation of host cellular STX6.
the expression of STX6 was up-regulated in esophageal squamous cell carcinoma samples, and its expression was significantly correlated with tumor size, histological differentiation, lymph node metastasis and depth
The compartment-specific interaction of Syntaxin 6 with v-SNARES VAMP3 (show VAMP3 Proteins) and VAMP4 (show VAMP4 Proteins) are controlled through an ability of Syntaxin 6 to sense cholesterol levels in the trans-Golgi network and recycling endosomes.
A dityrosine motif of Ang2 (show ANGPT2 Proteins) interacts with a highly conserved groove in Syntaxin 6.
Syntaxin 6 and VAMP4 (show VAMP4 Proteins) colocalize to the chlamydial inclusion.
Data indicate that depletion of VAMP4 (show VAMP4 Proteins), syntaxin 6, syntaxin 16 (show STX16 Proteins), and Vti1a (show VTI1A Proteins) disrupted the Golgi ribbon structure.
Data indicate that E3 ubiquitin ligase (show MUL1 Proteins) MARCH2 (show MARCH2 Proteins) co-immunoprecipitated and co-localized with CAL (show FBLIM1 Proteins) and syntaxin 6 (STX6), and show the ubiquitination of CFTR (show CFTR Proteins) by MARCH2 (show MARCH2 Proteins).
No pathogenic mutations are found in syntaxin 6 that are associated with risk of Parkinson's disease.
colocalization of ATP11B (show ATP11B Proteins) with fluorescent cisplatin and with vesicular trafficking proteins, such as STX6 and VAMP4 (show VAMP4 Proteins), strongly suggests that ATP11B (show ATP11B Proteins) contributes to secretory vesicular transport of cisplatin from Golgi to plasma membrane
Cholesterol modulates distribution of syntaxin 6 in insulin (show INS Proteins) granule membranes.
a novel mechanism showing how Salmonella acquires LAMP1 (show LAMP1 Proteins) through a SipC-Syntaxin6-mediated interaction probably to stabilize their niche in macrophages
Syntaxin 6 and Vti1b (show VTI1B Proteins) form a SNARE (show VTI1B Proteins) complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha (show TNF Proteins)
syntaxin 6 is required for rentry of IRAP (show IL1RN Proteins) from cell surface back into the insulin (show INS Proteins)-responsive complex
Involved in intracellular vesicle trafficking (By similarity).
, syntaxin 6
, syntaxin-like protein