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TAF4 Proteins

(TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa (TAF4))
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and vitamin D3 receptors. In addition, this subunit interacts with the transcription factor CREB, which has a glutamine-rich activation domain, and binds to other proteins containing glutamine-rich regions. Aberrant binding to this subunit by proteins with expanded polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases. [provided by RefSeq, Jul 2008].
TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa (TAF4) (AA 1-1085) protein (His tag) TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa (TAF4) (AA 1-1085) protein (His tag) TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa (TAF4) (AA 1-1085) protein (His tag) (ABIN3095791)

Crystallography grade TAF4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

TAF4 Proteins by Grade

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TAF4 Proteins by Origin

Find TAF4 Proteins for a variety of species such as anti-Human TAF4, anti-Candida albicans TAF4, anti-Saccharomyces cerevisiae TAF4. The species listed below are among those available. Click on a link to go to the corresponding products.

TAF4 Proteins by Source

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TAF4 Proteins by Protein Type

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TAF4 Proteins by Application

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Popular TAF4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Schizosaccharomyces pombe
Source Yeast
Validations
Cat. No. ABIN1653868
Quantity 1 mg
Datasheet Datasheet
Reactivity Saccharomyces cerevisiae
Source Yeast
Validations
Cat. No. ABIN1478191
Quantity 1 mg
Datasheet Datasheet

Aliases for TAF4 Proteins

TBP-associated factor 4 (Taf4) Proteins
Taf4p (TAF4) Proteins
TATA-box binding protein associated factor 4 (TAF4) Proteins
TATA-box binding protein associated factor 4 L homeolog (taf4.L) Proteins
CG5444 Proteins
d110 Proteins
Dmel\\CG5444 Proteins
dmTAF4 Proteins
dTAF4 Proteins
dTAFII110 Proteins
dTAF[[II]]110 Proteins
l(3)72Dj Proteins
p110 Proteins
SR3-3 Proteins
SY3-2 TAF110 Proteins
TAF Proteins
TAF2C Proteins
TAF2C1 Proteins
TAF4 Proteins
TAF4A Proteins
TAF110 Proteins
Taf110 Proteins
taf110 Proteins
TAFII110 Proteins
TAFII130 Proteins
TAFII135 Proteins
TAF[II]110 Proteins
TAF[[II]] Proteins
TAF[[II]]110 Proteins
Taf[[II]]110 Proteins
TFIID Proteins
TFIID 110 Proteins
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