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Human GATA3 Protein expressed in Wheat germ - ABIN1354834
Kuwahara, Yamashita, Shinoda, Tofukuji, Onodera, Shinnakasu, Motohashi, Hosokawa, Tumes, Iwamura, Lefebvre, Nakayama: The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-? and suppresses T(H)2 differentiation. in Nature immunology 2012
Show all 4 Pubmed References
Human GATA3 Protein expressed in HEK-293 Cells - ABIN2721729
Kao, Stankovic: Transactivation of human osteoprotegerin promoter by GATA-3. in Scientific reports 2015
Study identified the novel role of transcription factors GATA-2 (show GATA2 Proteins) and GATA-3 in suppressing MICA (show MICA Proteins)/B expression in HBV-infected human hepatoma cells.
The GATA3 rs3824662 A allele and AA genotype may be risk factors for the development of pediatric ALL especially B-ALL in the studied cohort of Egyptian patients. The AA genotype is associated with shorter DSF, increased incidence of relapse and poor prognosis in pediatric ALL.
Mutation in the GATA-3 gene is associated with hypoparathyroidism, deafness and renal dysplasia syndrome.
GATA3 is a reliable diagnostic marker for Neuroblastomas not only in scant/limited surgical specimens but also in cytologic samples, including air-dried touch imprints, which have previously been undescribed for this marker.
Dysregulation of JAM-A (show F11R Proteins) via p63 (show RPE65 Proteins)/GATA-3 signaling pathway occurs in squamous cell carcinomas of the head and neck.
FBXW7alpha inhibits breast cancer cells survival by promoting GATA3 degradation/destabilizing GATA3.
GATA3-driven expression of miR-503 inhibits prostate cancer progression by repressing ZNF217 expression.
MIR (show MLXIP Proteins)-720 suppresses M2 macrophage polarization by targeting GATA3; MIR (show MLXIP Proteins)-720 is down-regulated in breast cancer macrophages.
the model of mutually antagonistic differentiation programs driven by mutually exclusively expressed T-bet or GATA-3 does not completely explain natural CD4 (show CD4 Proteins) T cell priming outcomes
GATA3 expression is associated with breast carcinomas of luminal subtype and low histological grade.
RHS6 is a critical regulatory element for allergic airway inflammation and for coordinate regulation of Th2 cytokine genes by recruiting GATA3, SATB1 (show SATB1 Proteins), and IRF4 (show IRF4 Proteins).
MIF (show MIF Proteins)-deficient mice have reduced Nippostrongylus brasiliensis burden and mounted an enhanced type 2 immune response, including increased Gata3 expression and IL-13 (show IL13 Proteins) production in the mesenteric lymph nodes
study demonstrates a role for HOX5 (show HOXB5 Proteins) proteins in controlling lung inflammation during a model of allergic asthma. The increased inflammation in the Hox5 (show HOXB5 Proteins)-deficient mice was mediated by increased Th2 cell development, which was associated with regulation of Gata3 expression
Treg cell accumulation in intestinal tumours from APC (show APC Proteins)(min/+) mice was exclusively due to the increase in KLRG1 (show KLRG1 Proteins)(+) GATA3(+) Treg cells.
GATA3 abundance regulates the recombination propensity at the Tcrb locus.
impairment of trophoblast-specific GATA2 (show GATA2 Proteins)/GATA3 function could lead to early pregnancy failure
both Gata2 (show GATA2 Proteins) and Gata3 are redundantly required for differentiation of the serotonergic and glutamatergic neurons of the dorsal raphe
priming of T helper cells by IL-6 (show IL6 Proteins)-deficient antigen-presenting dendritic cells preferentially leads to accumulation of a subset of Follicular helper T cells characterized by high expression of GATA3 and IL-4 (show IL4 Proteins).
Gata3 was first expressed in all developing neurons, followed by a decrease in type I primary auditory neurons as they matured.
gata3 acts as a specific injury-induced proregenerative factor that is essential for the regenerative capacity in vertebrates
GATA2 (show GATA2 Proteins) and/or GATA3 are involved in the regulation of trophoblast-specific gene transcription in bovine trophoblast CT-1 (show SLC6A8 Proteins) cells
study identified rainbow trout and Atlantic salmon IL-4 (show IL4 Proteins)/13A, a homologue of mammalian Th2 cytokine genes IL-4 (show IL4 Proteins) and IL-13 (show IL13 Proteins); salmonid IL-4 (show IL4 Proteins)/13A and GATA-3 were found highly expressed in thymus, gill, and skin
T cells expressed low levels of GATA-3, which decreased with age.
The myocardial immune dysfunction induced by the change in expression levels of the transcription factors GATA-3 and T-bet may be involved in the process of post-resuscitation myocardial injury in a porcine model of cardiac arrest.
Pig GATA-3 cDNA was obtained by reverse transcription polymerase chain reaction (RT-PCR), using in silico cloning strategy based on pig dbEST (show BEST1 Proteins).
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.
GATA-binding factor 3
, trans-acting T-cell-specific transcription factor GATA-3
, GATA-binding protein 3
, transcription factor GATA-3
, GATA binding factor-3
, transcription factor xGATA-3
, transcription factor NF-E1c
, GATA binding protein 3
, putative amidase
, trans-acting T-cell-specific transcription factor GATA-3-like
, hematopoietic death receptor