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anti-Human TLR6 Antibodies:
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Human Monoclonal TLR6 Primary Antibody for FACS, IHC (p) - ABIN252495
Hajishengallis, Tapping, Harokopakis, Nishiyama, Ratti, Schifferle, Lyle, Triantafilou, Triantafilou, Yoshimura: Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll-like receptor 2-centred pattern recognition apparatus. in Cellular microbiology 2006
Show all 16 Pubmed References
Human Monoclonal TLR6 Primary Antibody for ELISA - ABIN4248135
Ganley-Leal, Liu, Wetzler: Toll-like receptor 2-mediated human B cell differentiation. in Clinical immunology (Orlando, Fla.) 2006
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Human Monoclonal TLR6 Primary Antibody for FACS - ABIN4360317
López, Palmer, Lawrence: Naïve T cells, unconventional NK and NKT cells, and highly responsive monocyte-derived macrophages characterize human cord blood. in Immunobiology 2014
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Human Monoclonal TLR6 Primary Antibody for FACS - ABIN4360316
Wong, Cheung, Ip, Lam: Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils. in American journal of respiratory cell and molecular biology 2007
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Human Polyclonal TLR6 Primary Antibody for ICC, ELISA - ABIN1003334
Takeda, Kaisho, Akira: Toll-like receptors. in Annual review of immunology 2003
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Human Polyclonal TLR6 Primary Antibody for IHC, ELISA - ABIN1003335
Janeway, Medzhitov: Innate immune recognition. in Annual review of immunology 2002
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Human Polyclonal TLR6 Primary Antibody for WB - ABIN550254
Into, Kiura, Yasuda, Kataoka, Inoue, Hasebe, Takeda, Akira, Shibata: Stimulation of human Toll-like receptor (TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induces apoptotic cell death after NF-kappa B activation. in Cellular microbiology 2004
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Human Polyclonal TLR6 Primary Antibody for IF, WB - ABIN550255
McGettrick, ONeill: The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction. in Molecular immunology 2004
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Human Monoclonal TLR6 Primary Antibody for FACS, IHC (p) - ABIN531987
Balmer, Arredondo, Samaco, LaSalle: MECP2 mutations in Rett syndrome adversely affect lymphocyte growth, but do not affect imprinted gene expression in blood or brain. in Human genetics 2002
Human Polyclonal TLR6 Primary Antibody for FACS, IF (p) - ABIN749573
Shmuel-Galia, Aychek, Fink, Porat, Zarmi, Bernshtein, Brenner, Jung, Shai: Neutralization of pro-inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis. in The EMBO journal 2016
recombinant NS1, expressed and purified from eukaryotic cells, induces cytokine production via TLR4 but not TLR2/6.
TLR6 role in Kawasaki disease susceptibility in African American family
The mRNA levels of Toll-like receptors TLR2, 6, and 9 were significantly elevated in the Kawasaki disease (KD) patient group versus the healthy controls.
Significant correlations with atherosclerosis susceptibility were found for the toll like receptor 1 (TLR1 (show TLR1 Antibodies)) rs5743551 polymorphism and toll like receptor 6 (TLR6) rs5743810 polymorphism.
Study concludes that genetic variation in the TLR10 (show TLR10 Antibodies)-TLR1-TLR6 gene cluster mediates responsiveness to organic dust, but indicates different signaling pathways for IL-6 (show IL6 Antibodies) and TNF-alpha (show TNF Antibodies). These studies provide new insight into the role of the TLR10 (show TLR10 Antibodies)-TLR1-TLR6 gene cluster and the innate immune response to organic dust.
Studied the relationship between polymorphisms in MBL (show MBL2 Antibodies), TLR1 (show TLR1 Antibodies), TLR2 and TLR6 encoding genes and stimulated IFN-gamma (show IFNG Antibodies) and IL-12 (show IL12A Antibodies) ex vivo production in BCG (show SLC11A1 Antibodies) osteitis survivors. Found that variant genotypes of the MBL2 (show MBL2 Antibodies) gene (if homozygous) and variant genotypes of the TLR2 gene (only heterozygotes present) are associated with low IFN-gamma (show IFNG Antibodies) production.
efficient method for preparation of the extracellular domain of human Toll-like receptor 6 (TLR6ED) in Escherichia coli using the bubbling cultivation method. Our preparation method improved the level of expression of TLR6ED into a soluble fraction as compared with typical cultivation using a rotary shaker. Circular dichroism (CD) experiments confirmed the structural formation of TLR6ED with secondary structure contents
Toll-like receptor 6 (TLR6) is significantly overexpressed in the hepatocytes of non-alcoholic fatty liver disease (NAFLD (show TSC2 Antibodies) patients compared to their normal counterparts.
study demonstrates a significant association between TLR4 (show TLR4 Antibodies) rs192791 and TLR6 rs1039559 SNPs and posttransplantation diabetes mellitus in renal transplantation recipients
Study showed that MyD88 Toll/interleukin-1 receptor (TIR) domain interacted with TLR5TIR but not with TLR6TIR. The solubility of both TLR5TIR and TLR6TIR were influenced by its binding partner MyD88TIR.
the cooperative role of TLR9 (show TLR9 Antibodies) with TLR2 or TLR6 receptors in sensing Brucella, was determined.
Data suggest that the transmembrane domains of Tlr4 (show TLR4 Antibodies) and Tlr6 have essential roles in Tlr4 (show TLR4 Antibodies)/Tlr6/Cd36 (show CD36 Antibodies) receptor multimerization and activation; disruption of receptor multimerization (here, using a recombinant peptide fragment from Tlr4 (show TLR4 Antibodies) transmembrane domain) reduces secretion of proinflammatory mediators from microglia and ultimately rescues neurons from death.
TLR6 knockout alleviates generation of myocardial fibrosis by suppressing collagen deposition.
Dengue virus NS1 (show IVNS1ABP Antibodies) protein is the viral protein responsible for the activation of TLR2 and TLR6 during Dengue virus infection
Hepatic expression of Tlr6, but not that of Tlr8 (show TLR8 Antibodies) is epigenetically controlled, and that the dysregulations of Tlr6 and Tlr8 (show TLR8 Antibodies) critically contribute to Testosterone (T)-induced persistent susceptibility to P. chabaudi malaria.
lipopeptides elicit TLR1/2 and TLR2/6 signaling in the endolysosomes, but not on the cell surface.
Transmembrane oligomeric form of Vibrio cholerae cytolysin (show PRF1 Antibodies) (VCC) triggers TLR2/TLR6-dependent proinflammatory responses in monocytes and macrophages.
long-term exposure to nicotine up-regulated the expression of TLR4 (show TLR4 Antibodies) and -6 via a JNK (show MAPK8 Antibodies)-related pathway, causing an exaggeration of the LPS (show TLR4 Antibodies)-induced local airway inflammation and increased airway hyperreactivity
The results demonstrate that inflammatory responses caused by ZNPs-activated macrophages strongly depend on TLR6-mediated MAPK (show MAPK1 Antibodies) signalling.
In total, 20, 27, and 26 SNPs were detected in TLR1 (show TLR1 Antibodies), TLR2, and TLR6, respectively; SNPs detected in TLR6 may represent species-specific function on the protein level in the wild boars and domestic pigs.
both TLR2 and TLR6 are important in the recognition of M. hyopneumoniae in porcine alveolar macrophages
phylogenetic analysis of the cytoplasmic regions of TLR genes suggested that the signal transduction pathway of TLR10 (show TLR10 Antibodies) was different from those of TLR1 (show TLR1 Antibodies) and TLR6
Variants in the TLR6 gene are associated with susceptibility to bovine TB.
TLR2, TLR1 (show TLR1 Antibodies), and TLR6 haev roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides by epithelial and stromal cells of bovine endometrium
The expression analysis showed similar expression profiles for TLR1 (show TLR1 Antibodies) and TLR6, which indicate a co-regulation of these two genes, TLR10 (show TLR10 Antibodies) had a different expression profile, pointing toward a stronger functional diversification compared to TLR1 (show TLR1 Antibodies) and TLR6.
Analysis of sequence variability and protein domain architectures for bovine peptidoglycan recognition protein 1 (show PGLYRP1 Antibodies) and Toll (show TLR4 Antibodies)-like receptors 2 and 6.
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.
toll-like receptor 1 type 1
, toll-like receptor 16
, toll-like receptor1