anti-NFKB2 Antibodies

298 Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) Antibodies from 28 manufacturers are available on www.antibodies-online.com.

Data Quality
  • 12
  • 89
Type
  • 298
    Primary antibodies
Antigen
  • 298
Reactivity
  • 288
  • 202
  • 143
  • 12
  • 11
Application
  • 230
  • 127
  • 90
  • 61
  • 56
Detection Method
  • 3
Host
  • 292
  • 6
Clonality
  • 275
  • 21
Clone
  • 3
  • 2
  • 1
  • 1
  • 1
Binding Specificity
  • 25
  • 20
  • 19
  • 18
  • 16
Conjugate
  • 226
  • 14
  • 8
  • 8
  • 7
Isotype
  • 155
  • 5
  • 1
  • 1
Format
  • 186
  • 12
298 Products
ReactivityHuman
Application WB
Order details Cat. No. ABIN3017388
$393.25
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IHC (p), WB
Order details Cat. No. ABIN3043293
$280.00
100 μg
Plus shipping costs $45.00
Delivery in 4 to 6 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IHC, WB
Order details Cat. No. ABIN2974614
$422.09
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IHC (p), WB
Order details Cat. No. ABIN3032047
$452.38
100 μg
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse (Murine)
Application IP, WB
Order details Cat. No. ABIN2854310
$466.18
100 μL
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityCow (Bovine), Horse (Equine), Human, Pig (Porcine), Rabbit, Rat (Rattus)
Application IHC, WB
Order details Cat. No. ABIN2779436
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN1873900
$363.06
100 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, IF, IHC, IP, WB
Order details Cat. No. ABIN3185875
$359.79
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, IHC, WB
Order details Cat. No. ABIN3180753
$359.79
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman
Application IF, IHC, WB
Order details Cat. No. ABIN3020406
$490.05
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman
Application IF, IHC, WB
Order details Cat. No. ABIN3020403
$490.05
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityMouse (Murine), Rat (Rattus)
Application IHC (p), WB
Order details Cat. No. ABIN3044018
$280.00
100 μg
Plus shipping costs $45.00
Delivery in 4 to 6 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, ICC, IF, IHC, IP, WB
Order details Cat. No. ABIN6256439
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, ICC, IF, IHC, IP, WB
Order details Cat. No. ABIN6255542
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IHC, WB
Order details Cat. No. ABIN6569453
$438.90
Plus shipping costs $45.00
Delivery in 12 to 14 Business Days
ReactivityHuman
Application IF, IHC (p), WB
Order details Cat. No. ABIN5584466
$577.33
100 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN6144574
$393.25
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman
Application ICC, IHC, WB
Order details Cat. No. ABIN1078411
$232.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
ReactivityCow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
Application IHC, WB
Order details Cat. No. ABIN2777546
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityChicken, Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
Application IF/ICC, IHC, IP, WB
Order details Cat. No. ABIN2971629
$323.60
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman, Mouse (Murine)
Application IF, IHC (p), WB
Order details Cat. No. ABIN197572
$357.50
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF, IHC (p), WB
Order details Cat. No. ABIN197118
$357.50
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application IF, IHC (p), WB
Order details Cat. No. ABIN5584461
$374.67
100 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IF, IHC (p), WB
Order details Cat. No. ABIN5584462
$374.67
100 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, ICC, IF, IHC, IP, WB
Order details Cat. No. ABIN6263614
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF, IHC, WB
Order details Cat. No. ABIN1870473
$429.13
100 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF, IHC, WB
Order details Cat. No. ABIN1870475
$429.13
100 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityMouse (Murine), Rat (Rattus)
Application IHC (p), WB
Order details Cat. No. ABIN3032045
$452.38
100 μg
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityCow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
Application IC, IF, IP, IHC, WB
Order details Cat. No. ABIN2705038
$487.50
200 μL
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF/ICC, IHC, WB
Order details Cat. No. ABIN2988213
$506.51
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
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NFKB2 Antigen Profile

Protein Summary

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF- kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. In a non-canonical activation pathway, the MAP3K14- activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. The NF-kappa-B heterodimeric RelB-p52 complex is a transcriptional activator. The NF-kappa-B p52-p52 homodimer is a transcriptional repressor. NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing. The proteasome-mediated process ensures the production of both p52 and p100 and preserves their independent function. p52 binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. p52 and p100 are respectively the minor and major form\; the processing of p100 being relatively poor. Isoform p49 is a subunit of the NF-kappa-B protein complex, which stimulates the HIV enhancer in synergy with p65 (By similarity).

Alternative names and synonyms associated with NFKB2

  • nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 (Nfkb2) antibody
  • lyt antibody
  • NF-kappaB2 antibody
  • p49 antibody
  • p49/p100 antibody
  • p50B antibody
  • p52 antibody

Protein level used designations for NFKB2

DNA-binding factor KBF2 , NF kappaB2 , nuclear factor NF-kappa-B p100 subunit , nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100

GENE ID SPECIES
18034 Mus musculus
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