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anti-Human FTHL17 Antibodies:
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Describe the first 46,XY PGD pedigree that may be attributed to mutations of the FTHL17 gene and speculate that the FTHL17 gene is involved in the testis-determining pathway and tumorigenesis.
FTHL17 encodes a ferritin-like protein without ferroxidase activity. Its restricted embryonic expression and partial nuclear localization suggest that this novel ferritin type may have functions other than iron storage.
This gene is orthologous to a mouse gene that encodes a ferritin heavy polypeptide-like protein and shows testis-specific expression.
ferritin, heavy polypeptide-like 17
, ferritin heavy polypeptide-like 17
, cancer/testis antigen 38