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anti-Human FZD10 Antibodies:
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Cow (Bovine) Polyclonal FZD10 Primary Antibody for WB - ABIN2776713
Omoto, Hayashi, Kitahara, Takeuchi, Ueoka: Autosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R). in Ophthalmic genetics 2004
Show all 2 Pubmed References
the selective expression of FZD10 in brain vascular endothelial cells points at a potential role of FZD10-Galpha13 signalling in central nervous system angiogenesis.
there was a strong inverse correlation between nuclear immunostaining scores for beta-catenin expression and expression patterns of FZD10
FZD10 transactivation causes the activation of the Dvl-Rac1-JNK pathway and is associated with the development/progression of synovial sarcomas
Data demonstrate that Wnt7b signals through Fzd1 and -10 and LRP5 and implicate these Wnt coreceptors in the regulation of lung airway and vascular development.
Interprets Wnt signals during embryonic mesoderm and neural induction.
Frizzled10 expression is very strong during embryonic development of the CNS and may play an essential role in spatial and temporal regulation during neural development.
Characterization of the Frizzled10-CreER transgenic mouse: an inducible Cre line for the study of Cajal-Retzius cell development.
Results suggest that Frizzed 10 mediates Wnt1 signalling to determine sensory neural differentiation in Xenopus in vivo and in mouse cell culture.
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
frizzled 10, seven transmembrane spanning receptor
, frizzled homolog 10
, seven transmembrane spanning receptor
, frizzled homolog 4
, frizzled homolog B
, frizzled 10B
, frizzled 9
, frizzled family receptor 10