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Full name:: Wingless-Type MMTV Integration Site Family, Member 8A Proteins (WNT8A)

On www.antibodies-online.com are 5 Wingless-Type MMTV Integration Site Family, Member 8A (WNT8A) Proteins from 4 different suppliers available. Additionally we are shipping WNT8A Antibodies (62) and WNT8A Kits (2) and many more products for this protein. A total of 73 WNT8A products are currently listed.

Synonyms:: CWNT-8C, Stra11, wnt-8, Wnt-8A, Wnt-8D, wnt8, WNT8A, Wnt8c, WNT8D, wu:fa20e02, wu:fe05d07, Xwnt-8, Xwnt8

list all proteins	Gene Name	GeneID	UniProt
Mouse WNT8A	WNT8A	20890	Q64527
	WNT8A	7478	Q9H1J5
Rat WNT8A	WNT8A	291678
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WNT8A Proteins (WNT8A) by Origin

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Relevant Pathways for WNT8A Proteins

WNT Signaling

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More Proteins for WNT8A Interaction Partners

Mouse (Murine) Wingless-Type MMTV Integration Site Family, Member 8A (WNT8A) interaction partners

Caudal Wnt8a is expressed only early somite stages. It is needed for normal anterior trunk development in the absence of Wnt3a (show WNT3A Proteins). Wnt8a and Wnt3a (show WNT3A Proteins) cooperate to maintain Fgf8 (show FGF8 Proteins) expression and stop premature Sox2 (show SOX2 Proteins) up-regulation in the axial stem cell niche.
Wnt8a expression depends on the presence of Fgf3 (show FGF3 Proteins) indicating a serial regulation between Fgf and Wnt (show WNT2 Proteins) signalling during otic placode induction and specification.
demonstrate that both the enlargement of the otic placode and the expansion of the Wnt8a expression domain can be rescued in Spry1 (show SPRY1 Proteins)/; Spry2 (show SPRY2 Proteins)/ embryos by reducing the gene dosage of Fgf10 (show FGF10 Proteins)
FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a.
The Wnt8A expression was evaluted in the resultant Tg(CAG-mWnt8A) embryos to identify mWnt8A misexpression.

Human Wingless-Type MMTV Integration Site Family, Member 8A (WNT8A) interaction partners

the WNT8A gene is involved in the susceptibility to HSCR (show EDNRB Proteins), and plays an important role in the occurrence and development of Hirschsprung's disease.
Expression and regulation of WNT8A mRNA in human tumor cell lines

Zebrafish Wingless-Type MMTV Integration Site Family, Member 8A (WNT8A) interaction partners

The results demonstrate that the argon plasma jet (show FBXL15 Proteins) has no adverse effects on fin regeneration and embryogenesis in zebrafish, and does not interrupt the (Wnt (show WNT2 Proteins))/beta-Catenin (show CTNNB1 Proteins)-signaling pathways.
These results indicated that maternal wnt8a is dispensable for the initial dorsal determination, but cooperates with zygotic wnt8a for ventrolateral and posterior tissue formation.
Wnt (show WNT2 Proteins) signaling balances specification of the cardiac and pharyngeal muscle fields.
Data suggest that Wnt3 (show WNT3A Proteins), Wnt3a (show WNT3A Proteins), and Wnt8a bind to their respective receptors (Fz8 (show FZD2 Proteins), Lrp6 (show LRP5 Proteins), and Lypd6 (show LYPD6 Proteins)) in ordered plasma membrane environments; ordered plasma membrane environments appear to be essential for binding of Wnt (show WNT2 Proteins) proteins to their receptor complexes and stimulation of downstream signaling activity.
Wnt8, in addition to its well-established role in posterior mesoderm patterning, also plays a later role as a factor that expands the renal progenitor pool prior to kidney morphogenesis.
Cortical depth and differential transport of vegetally localized dorsal and germ line determinants, Wnt8a, grip2a, and Dazl (show DAZL Proteins), in the zebrafish embryo have been presented.
Gain of function of Wnt8a results in the accumulation of beta-catenin (show CTNNB1 Proteins) into the nuclei of all cells of the gastrula from the margin to the animal pole.
A filopodia-based transport system for Wnt8a controls anteroposterior patterning of the neural plate during vertebrate gastrulation.
Wnt (show WNT2 Proteins) limits its own signaling activity in part via up-regulation of a transporter, slc35c1 that promotes terminal fucosylation and thereby limits Wnt (show WNT2 Proteins) activity.
Dynamic association with donor cell filopodia and lipid-modification are essential features of Wnt8a during patterning of the zebrafish neuroectoderm.

WNT8A Protein Profile

Protein Summary

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. It encodes a protein which shows 81% amino acid identity to the mouse Wnt8A protein.

Alternative names and synonyms associated with WNT8A

Wnt family member 8A (WNT8A)
Wnt family member 8A (wnt8a)
wingless-type MMTV integration site family, member 8A (Wnt8a)
wingless-type MMTV integration site family, member 8A (WNT8A)
Wnt family member 8A (Wnt8a)
wingless-type MMTV integration site family, member 8a (wnt8a)

CWNT-8C protein
Stra11 protein
wnt-8 protein
Wnt-8A protein
Wnt-8D protein
wnt8 protein
WNT8A protein
Wnt8c protein
WNT8D protein
wu:fa20e02 protein
wu:fe05d07 protein
Xwnt-8 protein
Xwnt8 protein

Protein level used designations for WNT8A

wingless-type MMTV integration site family, member 8A , protein Wnt-8a , protein Wnt-8a-like , protein Wnt-8d , stimulated by retinoic acid gene 11 protein , wingless-related MMTV integration site 8D , wnt-8 , WNT8d , wingless-related MMTV integration site 8A , etID309727.14 , protein Wnt-8a ORF1 , wnt8.1 , CWnt-8 , Wnt-8C , protein Wnt-8c

GENE ID	SPECIES
100072609	Equus caballus
471645	Pan troglodytes
540199	Bos taurus
549962	Xenopus (Silurana) tropicalis
100219521	Taeniopygia guttata
100342870	Oryctolagus cuniculus
100402422	Callithrix jacchus
100586052	Nomascus leucogenys
20890	Mus musculus
7478	Homo sapiens
481525	Canis lupus familiaris
291678	Rattus norvegicus
30122	Danio rerio
396543	Gallus gallus

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