Contactin 1 Proteins (CNTN1)

The protein encoded by CNTN1 is a member of the immunoglobulin superfamily. Additionally we are shipping Contactin 1 Antibodies (60) and Contactin 1 Kits (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CNTN1 1272 Q12860
CNTN1 12805 P12960
Rat CNTN1 CNTN1 117258 Q63198
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Top Contactin 1 Proteins at

Showing 7 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 20 to 21 Days
HOST_Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
HOST_HEK-293 Cells Human Fc Tag   10 μg Log in to see 5 to 8 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days

CNTN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine) ,

Top referenced Contactin 1 Proteins

  1. Human Contactin 1 Protein expressed in Human Cells - ABIN2002736 : Peles, Nativ, Campbell, Sakurai, Martinez, Lev, Clary, Schilling, Barnea, Plowman, Grumet, Schlessinger: The carbonic anhydrase domain of receptor tyrosine phosphatase beta is a functional ligand for the axonal cell recognition molecule contactin. in Cell 1995 (PubMed)
    Show all 5 references for 2002736

  2. Mouse (Murine) Contactin 1 Protein expressed in Human Cells - ABIN2008420 : Vinik, Erbas, Park, Pierce, Stansberry: Methods for evaluation of peripheral neurovascular dysfunction. in Diabetes technology & therapeutics 2001 (PubMed)
    Show all 4 references for 2008420

More Proteins for Contactin 1 (CNTN1) Interaction Partners

Human Contactin 1 (CNTN1) interaction partners

  1. CNTN1 is a new gene which can be regulated by RET (show RET Proteins)/PTC3 (show NCOA4 Proteins) (Ret proto-oncogene (show RET Proteins) and Ret-activating protein ELE1 (show NCOA4 Proteins)) rearrangement gene and the protein level of CNTN1 is increasing in thyroid cancer.

  2. Structurally, CASPR2 (show CNTNAP2 Proteins) is highly glycosylated and has an overall compact architecture. CASPR2 (show CNTNAP2 Proteins) associates with micromolar affinity with CNTN1 but, under the same conditions, it does not interact with any of the other members of the contactin family.

  3. CNTN1 promotes prostate cancer progression.

  4. High CNTN-1 expression is associated with metastasis in gastric cancer.

  5. CNTN-1 is closely related with multidrug resistance of lung adenocarcinoma.

  6. anti-CNTN1 IgG4 antibodies are associated with subacute onset of chronic inflammatory demyelinating polyneuropathy symptoms, sensory ataxia (show USP14 Proteins), and good response to corticosteroids.

  7. under hypoxia conditions, elevated HIF-1alpha (show HIF1A Proteins) seems to up-regulate contactin-1 expression and by this activate RhoA (show RHOA Proteins) and facilitate migration of cancer cells.

  8. activation of AKT (show AKT1 Proteins) plays a role in contactin-1-mediated downregulation of E-cadherin (show CDH1 Proteins).

  9. A high expression of CNTN1 was markedly associated with the regional lymph node metastasis of patients with oral squamous cell carcinoma.

  10. The expression of CNTN-1 is upregulated in esophageal squamous cell carcinoma tissue and is related to stage and lymphatic invasion. Thus, it may be involved in the pathogenesis & progression of esophageal squamous cell carcinoma.

Mouse (Murine) Contactin 1 (CNTN1) interaction partners

  1. Data indicate that Contactin-1 expression is dependent upon EBF (show EBF1 Proteins) factors; Cntn1 gene belongs to the expanding regulatory cascade driven by these transcriptional regulators so that changes in its activation may contribute to the Ebf2 (show EBF2 Proteins) null mutant phenotype

  2. Contactin-1 has roles in regulating myelination and nodal/paranodal domain organization in the central nervous system

  3. The phenotype of the Cntn1 mice arises from dysfunction in the brain, spinal cord or peripheral nervous system.

  4. Data show that TAG1 (show CNTN2 Proteins) and F3 act antagonistically to control SHH (show SHH Proteins)-induced proliferation: F3 suppresses SHH (show SHH Proteins)-induced GNP proliferation and induces differentiation, whereas TAG1 (show CNTN2 Proteins) antagonises F3.

  5. these findings indicate that precise spatio-temporal regulation of TAG-1 (show CNTN2 Proteins) and F3/contactin expression is critical for normal cerebellar morphogenesis

  6. F3/contactin and caspr/paranodin (show CNTNAP1 Proteins) traffic to the cell surface via a non-conventional pathway

  7. These data provide evidence of a role for contactin in selectively regulating the cell surface expression and current densities of TTX-R but not TTX-S Na+ channel isoforms in nociceptive DRG neurons.

  8. Contactin-1 is a functional receptor for neuroregulatory chondroitin sulfate-E.

  9. Thus, our results suggest a contribution by DRG Na(v)1.6, and possibly Contactin to neuropathic pain in the neuroma model in mice.

Contactin 1 (CNTN1) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Contactin 1 Proteins (CNTN1)

  • contactin 1 (CNTN1)
  • contactin 1 (cntn1)
  • contactin 1 (Cntn1)
  • contactin-1-like (LOC100521555)
  • AW495098 protein
  • CNTN protein
  • cntn-A protein
  • CNTN1 protein
  • F3 protein
  • F3/F11 protein
  • F3cam protein
  • F11 protein
  • GP135 protein

Protein level used designations for Contactin 1 Proteins (CNTN1)

contactin/F3/F11 , contactin 1 , Neural cell surface protein F3 , contactin-1 , contactin-1-like , glycoprotein gP135 , neural cell surface protein F3 , neural cell recognition molecule F11 , neural cell recognition protein

100049925 Equus caballus
378666 Xenopus laevis
451836 Pan troglodytes
574365 Macaca mulatta
100171863 Pongo abelii
100386201 Callithrix jacchus
100599154 Nomascus leucogenys
1272 Homo sapiens
12805 Mus musculus
117258 Rattus norvegicus
281705 Bos taurus
477641 Canis lupus familiaris
100342120 Oryctolagus cuniculus
100731131 Cavia porcellus
417786 Gallus gallus
101118005 Ovis aries
100521555 Sus scrofa
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