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Dynamin 1-Like Proteins (DNM1L)

The protein encoded by DNM1L is a member of the dynamin superfamily of GTPases. Additionally we are shipping Dynamin 1-Like Antibodies (122) and Dynamin 1-Like Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DNM1L 8562 O43583
DNM1L 74006 Q8K1M6
DNM1L 114114 O35303
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Top Dynamin 1-Like Proteins at

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Fruit Fly Un-conjugated   5 applications Log in to see 1 to 2 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

DNM1L Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

Rat (Rattus) ,

Top referenced Dynamin 1-Like Proteins

  1. Human DNM1L Protein expressed in Wheat germ - ABIN1351855 : Qi, Qvit, Su, Mochly-Rosen: A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity. in Journal of cell science 2013 (PubMed)
    Show all 4 references for ABIN1351855

More Proteins for Dynamin 1-Like (DNM1L) Interaction Partners

Rabbit Dynamin 1-Like (DNM1L) interaction partners

  1. The authors conclude that clathrin-independent compensatory endocytosis in umbrella cells is integrin regulated and occurs by a RhoA (show RHOA Proteins)- and dynamin (show DNM1 Proteins)-dependent pathway.

Human Dynamin 1-Like (DNM1L) interaction partners

  1. Dynamin-related protein 1 (Dpr1 (show DACT1 Proteins)) activates mitochondrial-dependent apoptosis and indicate that inhibiting Dpr1 (show DACT1 Proteins) function can protect against chlorpyrifos-induced cytotoxicity.

  2. Drp1 is in dynamic equilibrium on mitochondria in a fission-independent manner, and that fission factors such as actin filaments target productive oligomerization to fission sites.

  3. Dindings demonstrate for the first time, that Drp1 is required for Bax mitochondrial translocation, but Drp1-induced mitochondrial fragmentation alone is not sufficient to induce apoptosis in DLBCL cells.

  4. Haploinsufficiency of Drp1 abolished mitochondrial autophagy and exacerbated the development of heart failure.

  5. Results indicate that a multiprotein complex including PGAM5, Bax and Drp1 proteins specifically formed during intrinsic apoptosis induction.

  6. DNM1L has a critical role in regulating mitochondrial morphology and function [case report of two siblings]

  7. The results indicate that Drp1 (show CRMP1 Proteins)-dependent mitochondrial fission through MiD49 (show SMCR7 Proteins)/MiD51 (show SMCR7L Proteins) regulates cristae remodeling during intrinsic apoptosis.

  8. liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission

  9. that KIF1Bbeta affects mitochondrial dynamics through calcineurin (show PPP3CA Proteins)-dependent dephosphorylation of Dynamin-related protein 1 (DRP1), causing mitochondrial fission and apoptosis

  10. membrane-anchored Mff differentially regulates various Drp1 isoforms.

Mouse (Murine) Dynamin 1-Like (DNM1L) interaction partners

  1. knockdown of Mfn2 in adipo and osteogenesis and the overexpression of a dominant negative form of Drp1 during chondrogenesis resulted in a loss of differentiation ability

  2. Drp1 regulates mitochondrial transport in growing dendrites of Purkinje cells and is required for dendritic arborization.

  3. Mff cannot bind to assembly-deficient mutants of Drp1, suggesting that Mff selectively interacts with higher-order complexes of Drp1.

  4. Loss of Drp1 compromises the intrinsic bioenergetic function of axonal mitochondria, thus revealing a mechanism by which disrupting mitochondrial dynamics can cause dysfunction of axons.

  5. Drp1 is required for functionally active mitochondria, and supplementing with ATP can restore the defects induced by Drp1 suppression.

  6. These findings strongly suggest that Drp1 plays an important role in determining the fate of cells after irradiation via the regulation of mitochondrial dynamics.

  7. our in vivo observations clarify the role of mitochondrial fission in neurons, demonstrating that Drp1 ablation in adult forebrain neurons compromises critical neuronal functions without causing overt neurodegeneration.

  8. enhanced ERK (show EPHB2 Proteins) signaling in Drp1 (show CRMP1 Proteins)-knockdown macrophages is implicated in the potentiation of NLRP3 (show NLRP3 Proteins) inflammasome activation, via mediating mitochondrial localization of NLRP3 (show NLRP3 Proteins) to facilitate the assembly of NLRP3 (show NLRP3 Proteins) inflammasome

  9. DRP1 (show CRMP1 Proteins)-dependent apoptotic mitochondrial fission occurs independently of BAX (show BAX Proteins), BAK (show BAK1 Proteins) and APAF1 (show APAF1 Proteins) to amplify cell death by BID (show BID Proteins) and oxidative stress.

  10. membrane-anchored Mff differentially regulates various Drp1 isoforms.

Dynamin 1-Like (DNM1L) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.

Gene names and symbols associated with Dynamin 1-Like Proteins (DNM1L)

  • dynamin 1-like (dnm1l)
  • dynamin 1-like (DNM1L)
  • dynamin 1-like (LOC100229161)
  • dynamin 1-like (LOC100338814)
  • dynamin 1-like (LOC100369408)
  • dynamin related protein 1 (Drp1)
  • dynamin-like protein (PF10_0368)
  • dynamin-like protein (dyn1)
  • dynamin-like protein (cgd1_580)
  • dynamin-like protein (EHI_052740)
  • dynamin-like protein (PVX_092875)
  • dynamin-like protein (BBOV_II002980)
  • density-regulated protein (DENR)
  • dynamin 1-like (Dnm1l)
  • 18.m06247 protein
  • 6330417M19Rik protein
  • AI450666 protein
  • Dlp1 protein
  • DNM1L protein
  • Dnml1 protein
  • Dnmlp1 protein
  • DRP protein
  • Drp1 protein
  • DVLP protein
  • DYMPLE protein
  • EMPF protein
  • HDYNIV protein
  • MGC53850 protein
  • python protein
  • SMAP-3 protein
  • zgc:66163 protein

Protein level used designations for Dynamin 1-Like Proteins (DNM1L)

dynamin 1-like , dynamin-1-like protein , Dynamin-1-like protein , dynamin-1-like protein-like , dynamin related protein 1 , dynamin-like protein , smooth muscle cell associated protein-3 , smooth muscle cell-associated protein 3 , Dnm1p/Vps1p-like protein , dynamin family member proline-rich carboxyl-terminal domain less , dynamin-like protein 4 , dynamin-like protein IV , dynamin-related protein 1 , dymple , C-terminal region , N-terminal region , dynamin-like protein 1

379875 Xenopus laevis
393896 Danio rerio
418132 Gallus gallus
465266 Pan troglodytes
695388 Macaca mulatta
100229161 Taeniopygia guttata
100338814 Oryctolagus cuniculus
100369408 Saccoglossus kowalevskii
100380278 Salmo salar
100474116 Ailuropoda melanoleuca
100560647 Anolis carolinensis
411472 Apis mellifera
810525 Plasmodium falciparum 3D7
811008 Plasmodium falciparum 3D7
3371500 Cryptosporidium parvum Iowa II
3405942 Entamoeba histolytica HM-1:IMSS
5474863 Plasmodium vivax Sal-1
5478050 Babesia bovis T2Bo
8562 Homo sapiens
10059 Homo sapiens
74006 Mus musculus
114114 Rattus norvegicus
540892 Bos taurus
477649 Canis lupus familiaris
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