Dynamin 1-Like Protein (DNM1L) (AA 448-736) (His tag)
Quick Overview for Dynamin 1-Like Protein (DNM1L) (AA 448-736) (His tag) (ABIN7505315)
Target
See all Dynamin 1-Like (DNM1L) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 448-736
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Purification tag / Conjugate
- This Dynamin 1-Like protein is labelled with His tag.
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Sequence
- Asn 448-Trp 736
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Characteristics
- A DNA sequence encoding the Human DRP1 protein (O00429) (Asn 458-Trp 736) was expressed with a N-His tag.
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Dynamin 1-Like (DNM1L) (AA 1-736) protein (His tag)
custom-made DNM1L Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Dynamin 1-Like (DNM1L) (AA 1-710) protein (GST tag)DNM1L Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Dynamin 1-Like (DNM1L) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)DNM1L Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Dynamin 1-Like (DNM1L) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)DNM1L Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- Dynamin 1-Like (DNM1L)
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Alternative Name
- DRP1
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Background
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Abbreviation: DRP1
Target Synonym: Dynamin-1-like protein,DNM1L,Dnm1p/Vps1p-like protein (DVLP),Dynamin family member proline-rich carboxyl-terminal domain less (Dymple),Dynamin-like protein
Background: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into ring-like structures which wrap around the scission site to constict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Required for normal brain development. Facilitates developmentally-regulated apoptosis during neural tube development. Required for a normal rate of cytochrome c release and caspase activation during apoptosis. Also required for mitochondrial fission during mitosis. May be involved in vesicle transport.
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Molecular Weight
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Calculated MW: 30.58 kDa
Observed MW: 35 kDa
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UniProt
- O00429
Target
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