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anti-Hyaluronidase-1 (HYAL1) Antibodies

HYAL1 encodes a lysosomal hyaluronidase. Additionally we are shipping HYAL1 Proteins (25) and HYAL1 Kits (18) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HYAL1 3373 Q12794
HYAL1 15586 Q91ZJ9
HYAL1 367166 Q76HN1
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Top anti-HYAL1 Antibodies at

Showing 10 out of 113 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with HYAL1 / Hyaluronidase-1 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of HYAL1 / Hyaluronidase-1 Antibody (C-term) in HepG2 cell line lysates (35ug/lane). This demonstrates the HYAL1 antibody detected the HYAL1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), WB Anti-HYAL1 antibody,  Western blotting Lane 1: NRK Cell Lysate Lane 2: Mouse Liver Tissue Lysate Lane 3: Mouse Kidney Tissue Lysate Lane 4: SP2/0 Cell Lysate Anti-HYAL1 antibody,  ICC ICC: MCF-7 Cell 100 μg Log in to see 4 to 6 Days
Mouse Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 5 to 7 Days
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human endometrial cancer, using HYAL1, antibody at 1:500 dilution. WB Image Sample(30 ug whole cell lysate) A:293T 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC, IHC (p) Western Blot: HYAL1 Antibody [NBP1-83409] - Lane 1: Marker [kDa] 220, 112, 84, 47, 32, 26, 17.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human liver tissue.Lane 5: Human tonsil tissue Immunocytochemistry/Immunofluorescence: HYAL1 Antibody [NBP1-83409] - Staining of human cell line A-431 shows positivity in cytoplasm. 0.1 mL Log in to see 5 to 7 Days
Human Mouse Un-conjugated WB Western Blot analysis of HYAL1 expression in transfected 293T cell line by HYAL1 MaxPab polyclonal antibody.Lane 1: HYAL1 transfected lysate(27.83 KDa).Lane 2: Non-transfected lysate. HYAL1 MaxPab polyclonal antibody. Western Blot analysis of HYAL1 expression in human kidney. 50 μg Log in to see 9 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days

HYAL1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-HYAL1 Antibodies

  1. Human Polyclonal HYAL1 Primary Antibody for EIA, IHC (p) - ABIN952807 : Lanktree, Johansen, Anand, Davis, Miller, Yusuf, Hegele, ,: Genetic variation in hyaluronan metabolism loci is associated with plasma plasminogen activator inhibitor-1 concentration. in Blood 2010 (PubMed)
    Show all 3 references for ABIN952807

  2. Human Polyclonal HYAL1 Primary Antibody for IHC, IHC (p) - ABIN4320742 : Siiskonen, Poukka, Tyynelä-Korhonen, Sironen, Pasonen-Seppänen: Inverse expression of hyaluronidase 2 and hyaluronan synthases 1-3 is associated with reduced hyaluronan content in malignant cutaneous melanoma. in BMC cancer 2013 (PubMed)
    Show all 2 references for ABIN4320742

  3. Human Polyclonal HYAL1 Primary Antibody for WB - ABIN516763 : Papakonstantinou, Kouri, Karakiulakis, Klagas, Eickelberg: Increased hyaluronic acid content in idiopathic pulmonary arterial hypertension. in The European respiratory journal 2008 (PubMed)

  4. Human Polyclonal HYAL1 Primary Antibody for ELISA - ABIN314303 : Daginakatte, Gutmann: Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth. in Human molecular genetics 2007 (PubMed)

  5. Cow (Bovine) Polyclonal HYAL1 Primary Antibody for WB - ABIN2784343 : Poola, Abraham, Marshalleck, Yue, Lokeshwar, Bonney, Dewitty: Molecular risk assessment for breast cancer development in patients with ductal hyperplasias. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)

More Antibodies against HYAL1 Interaction Partners

Human Hyaluronidase-1 (HYAL1) interaction partners

  1. HAS2 (show HAS2 Antibodies) and HAS3 (show HAS3 Antibodies) were the only hyaluronan synthases detected, the expression of which was almost similar in NPs (show NPS Antibodies) and NM.

  2. The receiver-operating characteristic curve analyses demonstrated that each one had good sensitivity and specificity for distinguishing BC patients from non-BC ones (HYAL1, miR (show MLXIP Antibodies)-210, miR (show MLXIP Antibodies)-96, lncRNA-UCA1, 91.5 and ).

  3. Study showed that reduced HYAL1 expression was associated with endometrial carcinoma aggressiveness, which further supported the role of hyaluronan degradation in cancer progression.

  4. Results demonstrated that HYAL1 was C-mannosylated and suggest the possible role of C-mannosylation for secretion and enzymatic activity of HYAL1.

  5. Hyaluronan (HA) interacting proteins RHAMM (show HMMR Antibodies) and hyaluronidase (show HAase Antibodies) impact prostate cancer cell behavior and invadopodia formation in 3D HA-based hydrogels.

  6. In contrast to the previously described MPS IX patient, our three patients display a phenotype limited to the joints, suggesting that this is the primary manifestation of HYAL1 deficiency.

  7. Upregulation of HYAL1 expression in breast cancer promoted tumor cell proliferation, migration, invasion and angiogenesis.

  8. This is the first report showing high HYAL-1 levels in epithelial ovarian cancer.

  9. HYAL-1 and HAS1 (show HAS1 Antibodies) expression predicted BCa (show BLNK Antibodies) metastasis, and HYAL-1 expression also predicted disease-specific survival.

  10. HYAL1 overexpression is correlated with the malignant behavior of breast cancer.

Pig (Porcine) Hyaluronidase-1 (HYAL1) interaction partners

  1. results are consistent with a role for hyaluronan and hyaluronoglucosaminidase 1 and 2 in the development of the microscopic folds of the pig placenta during gestation

  2. the porcine hyaluronidase (show HAase Antibodies) cluster consisting of genes HYAL1, HYAL2 (show HYAL2 Antibodies) and HYAL3 (show HYAL3 Antibodies) was characterized

Cow (Bovine) Hyaluronidase-1 (HYAL1) interaction partners

  1. This study focuses on the investigation of the digestibility of glycosaminoglycans with different degrees of sulfation by bovine testicular hyaluronidase (show HAase Antibodies).

Mouse (Murine) Hyaluronidase-1 (HYAL1) interaction partners

  1. HYAL1 is necessary for the breakdown of intracellular HA in the cortex, whereas HYAL2 (show HYAL2 Antibodies) is essential for the degradation of extracellular HA in all kidney regions

  2. The activity of the processed form of Hyal-1 was largely underestimated.

  3. The knockdown of Hyal-1 results in an 80% decrease of total acid hyaluronidase (show HAase Antibodies) activity in the mouse liver, confirming that Hyal-1 is a key actor of hyaluronic acid catabolism in this organ.

  4. Chondroitin sulfate is a crucial determinant for skeletal muscle development/regeneration and improvement of muscular dystrophies through HYAL1

  5. both HYAL1 and beta-hexosaminidase (show HEXA Antibodies) cleave chondroitin sulfate, but it is a preferred substrate for beta-hexosaminidase (show HEXA Antibodies). These studies provide in vivo evidence to support and extend existing knowledge of GAG breakdown.

  6. Data show that Hyal-1, but not Hyal-3 (show HYAL3 Antibodies),is an ovarian regulator factor for follicle development, and show an interrelationship between this enzyme and the follistatin (show FST Antibodies)/activin (show Actbeta Antibodies)/Smad3 (show SMAD3 Antibodies) pathway.

  7. Endothelial surface layer degradation by chronic hyaluronidase (show HAase Antibodies) infusion induces proteinuria in apolipoprotein E (show APOE Antibodies)-deficient mice

  8. Characterization of the murine hyaluronidase (show HAase Antibodies) gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 (show NAT6 Antibodies) and Hyal3 (show HYAL3 Antibodies).

  9. Hyal1 null mice had evidence of osteoarthritis with a loss of proteoglycans at early ages.

  10. Hyaluronidase (show HAase Antibodies) induces ovarian granulosa cell apoptosis and is involved in follicular atresia.

HYAL1 Antigen Profile

Protein Summary

This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Hyaluronidase-1 (HYAL1) Antibodies

  • hyaluronoglucosaminidase 1 (HYAL1) antibody
  • hyaluronoglucosaminidase 1 (Hyal1) antibody
  • Hya1 antibody
  • Hyal-1 antibody
  • LUCA1 antibody
  • NAT6 antibody

Protein level used designations for anti-Hyaluronidase-1 (HYAL1) Antibodies

hyaluronidase-1 , luCa-1 , lung carcinoma protein 1 , plasma hyaluronidase , tumor suppressor LUCA-1 , hyal-1 , hyaluronidase 1 , hyaluronoglucosaminidase-1

608602 Canis lupus familiaris
3373 Homo sapiens
404698 Sus scrofa
515397 Bos taurus
15586 Mus musculus
367166 Rattus norvegicus
Selected quality suppliers for anti-HYAL1 (HYAL1) Antibodies
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