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anti-Integrin-Binding Sialoprotein (IBSP) Antibodies

The protein encoded by IBSP is a major structural protein of the bone matrix. Additionally we are shipping Integrin-Binding Sialoprotein Kits (13) and Integrin-Binding Sialoprotein Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IBSP 25373 P24090
IBSP 15891 Q61711
IBSP 3381 P21815
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Top anti-Integrin-Binding Sialoprotein Antibodies at antibodies-online.com

Showing 10 out of 82 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB IBSP Antibody (N-term) (ABIN658035) western blot analysis in CEM cell ... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-IBSP Antibody Titration: 1.25ug/mlELISA Titer: 1:625... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated EIA, IHC (fro), IF, IHC (p), RIA, WB 0.1 mg Log in to see 6 to 8 Days
$698.50
Details
Human Chicken Un-conjugated EIA, FACS, IF, IHC (p), RIA, WB 0.1 mg Log in to see 6 to 8 Days
$588.50
Details
Mouse Rabbit Un-conjugated IHC (p), WB Anti-Bone Sialoprotein antibody, Western blotting Lane 1: Rat Liver Ti... Anti-Bone Sialoprotein antibody, IHC(P) IHC(P): Rat Liver Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Bone Sialoprotein antibody, IHC(P) IHC(P): Human Osteosarcoma Tis... 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rat Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$698.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details

IBSP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus) , , , ,

Mouse (Murine) , , , ,

Human , , , ,
, , , ,

Top referenced anti-Integrin-Binding Sialoprotein Antibodies

  1. Human Monoclonal IBSP Primary Antibody for EIA, IHC (fro) - ABIN191977 : Ibrahim, Leong, Sanchez-Sweatman, Khokha, Sodek, Tenenbaum, Ganss, Cheifetz: Expression of bone sialoprotein and osteopontin in breast cancer bone metastases. in Clinical & experimental metastasis 2001 (PubMed)
    Show all 8 references for ABIN191977

  2. Human Polyclonal IBSP Primary Antibody for EIA, FACS - ABIN191813 : Karmatschek, Maier, Seibel, Woitge, Ziegler, Armbruster: Improved purification of human bone sialoprotein and development of a homologous radioimmunoassay. in Clinical chemistry 1997 (PubMed)
    Show all 4 references for ABIN191813

  3. Human Polyclonal IBSP Primary Antibody for IF (p), IHC (p) - ABIN748838 : Yang, Hai, Qin, Ti, Shangguan, Zhao, Wiggins, Liu, Feng, Chang, Wang, Liu: Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a ?-catenin-dependent manner. in Molecular and cellular biology 2013 (PubMed)
    Show all 2 references for ABIN748838

  4. Human Polyclonal IBSP Primary Antibody for WB - ABIN658035 : Yerges, Klei, Cauley, Roeder, Kammerer, Moffett, Ensrud, Nestlerode, Marshall, Hoffman, Lewis, Lang, Barrett-Connor, Ferrell, Orwoll, Zmuda: High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009 (PubMed)
    Show all 2 references for ABIN658035

  5. Human Polyclonal IBSP Primary Antibody for WB - ABIN2774907 : Barnes, Javed, Waller, Kamal, Hebert, Hassan, Bellahcene, Van Wijnen, Young, Lian, Stein, Gerstenfeld: Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. in Cancer research 2003 (PubMed)

More Antibodies against Integrin-Binding Sialoprotein Interaction Partners

Mouse (Murine) Integrin-Binding Sialoprotein (IBSP) interaction partners

  1. OPN (show SPP1 Antibodies) produced by hematogenous macrophages induces astrocyte process extension toward the infarct border zone, which may contribute to repair of the ischemic neurovascular unit following stroke

  2. During the priming phase of liver regeneration, osteopontin (show SPP1 Antibodies) enhances the recruitment of macrophages and neutrophils, and triggers hepatocyte proliferation through Kupffer cell-derived IL-6 (show IL6 Antibodies) release and the downstream activation of Stat3 (show STAT3 Antibodies).

  3. OPN (show SPP1 Antibodies) deficiency accelerated the spontaneous development of colitis in mice with disrupted gut (show GUSB Antibodies) microbiota and macrophage phagocytic activity.

  4. mechanical stretch (MS) directly increased OPN (show SPP1 Antibodies) protein expression and secretion in vascular smooth muscle cells.

  5. OPN (show SPP1 Antibodies) may modulate psoriasis-like inflammation through altering lymphocyte distribution in skin and draining lymph nodes and by inducing IL-17 (show IL17A Antibodies) expression of inflammatory T cells.

  6. Osteopontin (show SPP1 Antibodies) is expressed in the oviduct and promotes fertilization and preimplantation embryo development.

  7. BSP (show KLK6 Antibodies) has a role in mouse cementum and craniofacial bone mineralization

  8. OPN (show SPP1 Antibodies) actually contributes to the development of gastric cancer.

  9. Hypergravity promoted OPN (show SPP1 Antibodies) expression in osteoblasts by facilitating focal adhesion assembly, strengthening actin bundles, and increasing Runx2 (show RUNX2 Antibodies) expression.

  10. lentiviral-OPN (show SPP1 Antibodies) short hairpin RNA ameliorates the inflammatory response and bone destruction in mice with collagen-induced arthritis. Therefore, OPN (show SPP1 Antibodies) may be a potential therapeutic target for rheumatoid arthritis.

Human Integrin-Binding Sialoprotein (IBSP) interaction partners

  1. Our results suggest that SSEA (show MPST Antibodies)-4 is a specific cell surface antigen (show CD53 Antibodies) that can be used to identify dental pulp stem cells.

  2. the strong correlation between bone sialoprotein (show CRISP1 Antibodies) and OPN (show SPP1 Antibodies) and papillary thyroid carcinoma suggests a role for BSP (show KLK6 Antibodies) and OPN (show SPP1 Antibodies) in calcification and tumor progression of papillary thyroid carcinoma

  3. oxidized low-density lipoprotein-induced expression dependent on Runx2 (show RUNX2 Antibodies) expression

  4. Bone sialoprotein (show CRISP1 Antibodies) could be a key mediator of the hypertrophic chondrocytes-induced angiogenesis of osteoarthritis.

  5. Current evidence demonstrates that BSP (show KLK6 Antibodies) and OPN (show SPP1 Antibodies), play significant roles in bone metastasis of osteotropic malignancies derived from breast, prostate, lung, thyroid, and multiple myeloma. [review]

  6. High expression of bone sialoprotein (show CRISP1 Antibodies) in breast neoplasms was associated with cytokeratin (show KRT4 Antibodies)-positive cells in bone marrow, but not with lymph node metastasis.

  7. results indicate that FGF2 (show FGF2 Antibodies) increases BSP (show KLK6 Antibodies) transcription by targeting the FRE (show FRZB Antibodies) and AP1 (show FOSB Antibodies) elements in the proximal promoter of the human BSP (show KLK6 Antibodies) gene.

  8. BSP (show KLK6 Antibodies) silencing decreased the integrin alphavbeta3 (show ITGAV Antibodies) and beta3 levels, in turn inhibiting cell migration and invasion and decreasing the ability of the cells to metastasize to bone.

  9. IBSP mRNA is over expressed in carotid atheroma plaque (3.74 fold, p = 1.41E-09) in an intraindividual comparison.

  10. High BSP (show KLK6 Antibodies) expression occurs in a significant subset of high-grade glioma patients and predicts a poorer outcome

Integrin-Binding Sialoprotein (IBSP) Antigen Profile

Protein Summary

The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.

Gene names and symbols associated with IBSP

  • integrin-binding sialoprotein (IBSP) antibody
  • integrin-binding sialoprotein (ibsp) antibody
  • integrin-binding sialoprotein (LOC100344425) antibody
  • alpha-2-HS-glycoprotein (Ahsg) antibody
  • integrin binding sialoprotein (Ibsp) antibody
  • integrin-binding sialoprotein (Ibsp) antibody
  • secreted phosphoprotein 1 (Spp1) antibody
  • 2AR antibody
  • Aa2-066 antibody
  • Apl-1 antibody
  • BNSP antibody
  • Bsp antibody
  • BSP-II antibody
  • Bsp2 antibody
  • BSPI antibody
  • BSP II antibody
  • BSPII antibody
  • Eta antibody
  • ETA-1 antibody
  • IBSP antibody
  • OP antibody
  • Opn antibody
  • Opnl antibody
  • pp63 antibody
  • Ric antibody
  • SP-II antibody
  • Spp-1 antibody

Protein level used designations for IBSP

integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) , integrin-binding sialoprotein , 59 kDa bone sialic acid-containing protein , BSP , alpha 2 HS-glycoprotein alpha 2 (fetuin) , fetuin-A , glycoprotein PP63 , phosphorylated N-glycoprotein pp63 , bone sialoprotein 2 , bone sialoprotein II , cell-binding sialoprotein , BSP II , integrin binding sialoprotein , Bone sialoprotein 2 , 44 kDa bone phosphoprotein , bone sialoprotein 1 , calcium oxalate crystal growth inhibitor protein , early T-lymphocyte activation 1 protein , minopontin , osteopontin , osteopontin-like protein

GENE ID SPECIES
471249 Pan troglodytes
609146 Canis lupus familiaris
701835 Macaca mulatta
100192352 Xenopus laevis
100271750 Xenopus (Silurana) tropicalis
100344425 Oryctolagus cuniculus
25373 Rattus norvegicus
15891 Mus musculus
3381 Homo sapiens
24477 Rattus norvegicus
281233 Bos taurus
396071 Gallus gallus
397137 Sus scrofa
20750 Mus musculus
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