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Interleukin 17 Receptor A Proteins (IL17RA)

Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. Additionally we are shipping IL17RA Antibodies (196) and IL17RA Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IL17RA 23765 Q96F46
IL17RA 312679  
IL17RA 16172 Q60943
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Top IL17RA Proteins at

Showing 10 out of 35 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
HOST_Human Cells Human His tag,Fc Tag 100 μg Log in to see 16 Days
HOST_Human Cells Mouse Fc Tag 100 μg Log in to see 16 Days
HOST_Human Cells Rat Fc Tag 100 μg Log in to see 16 Days
HOST_Human Cells Cynomolgus Fc Tag 100 μg Log in to see 16 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
HOST_HEK-293 Cells Human His tag 50 μg Log in to see 2 to 3 Days
HOST_HEK-293 Cells Human Fc Tag,AVI tag,Biotin Biotinylated Human IL-17 RA, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. Measured by its binding ability in a functional ELISA. Immobilized Human IL-17A, Tag Free  with a linear range of 1.2-9.8 ng/mL. 200 μg Log in to see 5 Days
HOST_Mammalian Cells Human Fc Tag   50 μg Log in to see 5 Days

IL17RA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
, , , , , ,
Rat (Rattus) ,
, ,
Mouse (Murine) , , ,
, ,

Top referenced IL17RA Proteins

  1. Human IL17RA Primary Antibody for - ABIN2181343 : Puel, Cypowyj, Bustamante, Wright, Liu, Lim, Migaud, Israel, Chrabieh, Audry, Gumbleton, Toulon, Bodemer, El-Baghdadi, Whitters, Paradis, Brooks, Collins, Wolfman, Al-Muhsen, Galicchio, Abel, Picard et al.: Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. ... in Science (New York, N.Y.) 2011 (PubMed)
    Show all 2 references for ABIN2181343

  2. Rat (Rattus) IL17RA Primary Antibody for - ABIN2009274 : Schwandner, Yamaguchi, Cao: Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transduction. in The Journal of experimental medicine 2000 (PubMed)
    Show all 2 references for ABIN2009274

  3. Cynomolgus IL17RA Primary Antibody for - ABIN2009892 : Toy, Kugler, Wolfson, Vanden Bos, Gurgel, Derry, Tocker, Peschon: Cutting edge: interleukin 17 signals through a heteromeric receptor complex. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 2 references for ABIN2009892

More Proteins for Interleukin 17 Receptor A (IL17RA) Interaction Partners

Human Interleukin 17 Receptor A (IL17RA) interaction partners

  1. It has been shown that IL-17 (show IL17A Proteins) can be produced by enteroendocrine chromogranin A (show CHGA Proteins)-positive cells as well as by goblet cells in the human colon.

  2. Results suggest that IL-17 (show IL17A Proteins)-IL-17R interaction in GSCs induces an autocrine/paracrine cytokine feedback loop, which may provide an important signaling component for maintenance/self-renewal of GSCs.

  3. High IL-17RA expression is associated with Intrahepatic Cholangiocarcinoma.

  4. Identified the IL17RA rs4819554 SNP as a risk factor for psoriasis.

  5. IL-17 receptor A and adenosine deaminase 2 (show CECR1 Proteins) deficiency due to deletion mutations was found in siblings with chronic mucocutaneous candidiasis and chronic systemic inflammation.

  6. In vitro, CSE stimulation significantly increased IL-17F and IL-17R in 16HBE (2.5%) and A549 (5%) while IL-17A and IL-17F in PBMC (10%). IL-17A and CSE stimulation, rather than CSE or rhIL-17A alone, increased proliferation in 16HBE and apoptosis in A549

  7. The data indicate that the genetic variants of rs2275913 in IL-17A, rs763780 in IL-17F, and rs4819554 in IL-17RA may not play a role in the pathogenesis of preeclampsia in Chinese Han women.

  8. IL17F (show IL17F Proteins) and IL17RA polymorphisms modulate susceptibility to cerebral malaria(CM) and provide evidence that IL-17F (show IL17F Proteins) protects against CM.

  9. Increased expression of IL-17RA plays an important role in gastric cancer progression, migration and prognosis.

  10. Both genetic variants of IL-17R (rs882643 and rs2241049) were associated with PGD (show PGD Proteins). This confirms a genetic predisposition toward PGD (show PGD Proteins) and suggests a role of IL-17 (show IL17A Proteins) in driving neutrophilia in PGD (show PGD Proteins).

Mouse (Murine) Interleukin 17 Receptor A (IL17RA) interaction partners

  1. IL-17RA contributes to experimental glomerulonephritis, with IL-17RA expression on both leukocytes and stromal cells being required for the full expression of nephritogenic humoral immunity.

  2. IL-17RA in non hematopoietic cells regulates recruitment of neutrophils to the lung during the adaptive phase of the immune response.

  3. Bronchial epithelial TLR2/IL17R signaling crosstalk is necessary for lung IL17 (show IL17A Proteins) homeostasis and is compromised by morphine.

  4. IL-17 (show IL17A Proteins) signaling through IL-17RA is an important driver of lung inflammation and airway hyperresponsiveness.

  5. results suggest that the p38alpha (show MAPK14 Proteins)-MKP-1 (show DUSP1 Proteins) signaling axis links IL-17R signaling in tissue-resident cells to autoimmune inflammation dependent on infiltrating T(H)17 cells.

  6. There were no significant differences in clinical scores and numbers of infiltrating eosinophils among IL-25KO, TSLPR (show CRLF2 Proteins) KO, and wild-type mice.

  7. IL-17RA signaling is critical for the development of renal pathology in autoimmune glomerulonephritis.IL-17 enhanced the production of proinflammatory cytokines and chemokines from tubular epithelial cells.

  8. Il17ra appears to be a novel modulator of monocyte phenotype and possible therapeutic target in renal fibrosis

  9. IL-17 (show IL17A Proteins) expression is higher in C57BL/6 versus BALB/c cornea after infection and that the latter group has more MerTK (show MERTK Proteins)+ cells.

  10. It was concluded that TLR signaling can directly stimulate the expression of IL-17RA, but not IL-17RC (show IL17RC Proteins), in neuroglial cells, which functionally respond to IL-17A (show IL17A Proteins) by secreting chemokines, and accelerating CD4 (show CD4 Proteins) cell migration.

IL17RA Protein Profile

Protein Summary

Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor\; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.

Gene names and symbols associated with IL17RA

  • interleukin 17 receptor A (IL17RA)
  • interleukin 17 receptor A (Il17ra)
  • AW538159 protein
  • CANDF5 protein
  • CD217 protein
  • Cdw217 protein
  • hIL-17R protein
  • IL-17RA protein
  • Il17r protein
  • VDw217 protein

Protein level used designations for IL17RA

IL-17 receptor A , interleukin-17 receptor A , IL-17RA

418158 Gallus gallus
23765 Homo sapiens
312679 Rattus norvegicus
16172 Mus musculus
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