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The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Additionally we are shipping IL27 Antibodies (150) and IL27 Proteins (26) and many more products for this protein.
Showing 10 out of 48 products:
Mouse (Murine) IL27 ELISA Kit for Sandwich ELISA - ABIN1672803
Larousserie, Charlot, Bardel, Froger, Kastelein, Devergne: Differential effects of IL-27 on human B cell subsets. in Journal of immunology (Baltimore, Md. : 1950) 2006
Show all 3 references for ABIN1672803
Human IL27 ELISA Kit for Sandwich ELISA - ABIN1672802
Larousserie, Bardel, Pflanz, Arnulf, Lome-Maldonado, Hermine, Brégeaud, Perennec, Brousse, Kastelein, Devergne: Analysis of interleukin-27 (EBI3/p28) expression in Epstein-Barr virus- and human T-cell leukemia virus type 1-associated lymphomas: heterogeneous expression of EBI3 subunit by tumoral cells. in The American journal of pathology 2005
IL-27 attenuates epithelial-mesenchymal transition in alveolar epithelial cells in the absence or presence of TGF-beta1 (show TGFB1 ELISA Kits) through the JAK (show JAK3 ELISA Kits)/STAT (show STAT1 ELISA Kits) and TGF-beta (show TGFB1 ELISA Kits)/Smad (show SMAD1 ELISA Kits) signalling pathways.
results provided new insights into the effect of IL-27 on the TNF-alpha (show TNF ELISA Kits) mediated activation of human coronary artery endothelial cells in atherosclerotic vascular inflammation
The 153109 of the IL27 (show EBI3 ELISA Kits) gene may be associated with the susceptibility to CHD (show CHDH ELISA Kits), including atrial septal defect and ventricular septal defect.
It is biologically plausible that SNPs in IL-27 may have effect on individual susceptibility to pre-eclampsia.
IL-27 induced IDO (show IDO1 ELISA Kits) or PD-L1 (show CD274 ELISA Kits) expression in monocytes and in human PC3 (show PCSK1 ELISA Kits) prostate and A549 lung cancer cells
An IL-27/Lag3 (show LAG3 ELISA Kits) axis enhances Foxp3 (show FOXP3 ELISA Kits)+ regulatory T cell-suppressive function and therapeutic efficacy.
The Serum IL-27 levels were negatively correlated with neuromyelitis optica spectrum disorders severity and spinal cord lesion length.
IL-27 gene rs153109 A/G SNP may be involved in susceptibility to BD in the Iranian population.
Serum IL-27 and IL-27-producing T cells, are involved in the pathogenesis of pemphigus.
The level of interleukin 27 is increased in peripheral blood mononuclear cells of patients with rheumatoid arthritis or osteoarthritis.
IL-27 is one of the limited unique cytokines directly acting on hematopoietic stem cells (HSCs) to promote differentiation into myeloid progenitors during emergency myelopoiesis.
These results provide the first evidences that Fli-1 (show FLI1 ELISA Kits) positively regulates LPS (show TLR4 ELISA Kits)-induced IL-27 production in macrophages
of autocrine/paracrine mechanisms involving IL-27 in adipocytes under conditions of inflammatory stress that may link obesity with inflammatory diseases.
Increased IL-27 expression in bleomycin-induced pulmonary fibrosis was noted.
IL-27 induces the endothelial differentiation in cardiac resident stem cells through STAT3 (show STAT3 ELISA Kits)/Pim-1 (show PIM1 ELISA Kits) signaling pathway.
demonstrate that suppression mediated by interferon (show IFNA ELISA Kits) and IL-27 is a negative feedback mechanism for group 2 innate lymphoid cells function in vivo
Natural killer cells-dendritic cells interaction elicits a positive feedback loop for IFN-gamma (show IFNG ELISA Kits) and IL-27 production.
demonstrate the essential role of IL-27 signaling in regulating immune responses to extracellular protozoan infections
IL-27 regulates enhanced susceptibility to S. aureus pneumonia following influenza infection, potentially through the induction of IL-10 (show IL10 ELISA Kits) and suppression of IL-17 (show IL17A ELISA Kits).
The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
, IL-27 p28 subunit
, IL-27 subunit alpha
, interleukin 30
, interleukin-27 subunit alpha
, interleukin 27 p28 subunit
, interluekin 27