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The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Additionally we are shipping IL27 Antibodies (150) and IL27 Proteins (27) and many more products for this protein.
Showing 10 out of 41 products:
Mouse (Murine) IL27 ELISA Kit for Sandwich ELISA - ABIN1672803
Larousserie, Charlot, Bardel, Froger, Kastelein, Devergne: Differential effects of IL-27 on human B cell subsets. in Journal of immunology (Baltimore, Md. : 1950) 2006
Show all 3 references for ABIN1672803
Human IL27 ELISA Kit for Sandwich ELISA - ABIN1672802
Larousserie, Bardel, Pflanz, Arnulf, Lome-Maldonado, Hermine, Brégeaud, Perennec, Brousse, Kastelein, Devergne: Analysis of interleukin-27 (EBI3/p28) expression in Epstein-Barr virus- and human T-cell leukemia virus type 1-associated lymphomas: heterogeneous expression of EBI3 subunit by tumoral cells. in The American journal of pathology 2005
Interleukin-27 rs 153109 Single Nucleotide Polymorphism is associated with responses to therapy in Hepatitis C.
this study shows that IL-27 gene polymorphism is genetic risk factor for systemic lupus erythematosus in the Polish population, and that it predicts disease phenotype
Data indicate that the CC genotype of interleukin 27 (IL-27) single nucleotide polymorphism rs153109 was significantly more prevalent in pre-eclampsia (PE) cases than controls.
IL-27 is a viable candidate biomarker to identify bacterial infection among ED patients and is comparable with PCT (show UROD ELISA Kits).
The inhibition of Th17 cells by IL-27 is vital for the maintenance of the feto-maternal tolerance and the prevention of lupus, multiple sclerosis, autoimmune uveitis, immune thrombocytopenia and atherosclerosis
Our results showed that the IL-27 2905T/G genotypes were associated with decreased the susceptibility and development of cervical cancer in Chinese Han population.
the genetic polymorphisms of IL-27 rs153109 and rs181206 may be involved in the progression of human cancers and diseases.
Findings demonstrated that IL-27 and IL-27R (show IL27RA ELISA Kits) were elevated in multiple sclerosis lesions and that local IL-27 can modulate immune properties of astrocytes and infiltrating immune cells
IL-27 attenuates epithelial-mesenchymal transition in alveolar epithelial cells in the absence or presence of TGF-beta1 (show TGFB1 ELISA Kits) through the JAK (show JAK3 ELISA Kits)/STAT (show STAT1 ELISA Kits) and TGF-beta (show TGFB1 ELISA Kits)/Smad (show SMAD1 ELISA Kits) signalling pathways.
results provided new insights into the effect of IL-27 on the TNF-alpha (show TNF ELISA Kits) mediated activation of human coronary artery endothelial cells in atherosclerotic vascular inflammation
An IL-27/Lag3 (show LAG3 ELISA Kits) axis enhances Foxp3 (show FOXP3 ELISA Kits)+ regulatory T cell-suppressive function and therapeutic efficacy.
IL-27 is one of the limited unique cytokines directly acting on hematopoietic stem cells (HSCs) to promote differentiation into myeloid progenitors during emergency myelopoiesis.
These results provide the first evidences that Fli-1 (show FLI1 ELISA Kits) positively regulates LPS (show TLR4 ELISA Kits)-induced IL-27 production in macrophages
of autocrine/paracrine mechanisms involving IL-27 in adipocytes under conditions of inflammatory stress that may link obesity with inflammatory diseases.
Increased IL-27 expression in bleomycin-induced pulmonary fibrosis was noted.
IL-27 induces the endothelial differentiation in cardiac resident stem cells through STAT3 (show STAT3 ELISA Kits)/Pim-1 (show PIM1 ELISA Kits) signaling pathway.
demonstrate that suppression mediated by interferon (show IFNA ELISA Kits) and IL-27 is a negative feedback mechanism for group 2 innate lymphoid cells function in vivo
Natural killer cells-dendritic cells interaction elicits a positive feedback loop for IFN-gamma (show IFNG ELISA Kits) and IL-27 production.
demonstrate the essential role of IL-27 signaling in regulating immune responses to extracellular protozoan infections
IL-27 regulates enhanced susceptibility to S. aureus pneumonia following influenza infection, potentially through the induction of IL-10 (show IL10 ELISA Kits) and suppression of IL-17 (show IL17A ELISA Kits).
The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
, IL-27 p28 subunit
, IL-27 subunit alpha
, interleukin 30
, interleukin-27 subunit alpha
, interleukin 27 p28 subunit
, interluekin 27