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IL-27 Products

(Interleukin 27 (IL27))

Categories

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008].

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Featured IL-27 Categories

IL-27 Antibodies

High quality antibodies with extensive validation data.

IL-27 ELISA Kits

Reliable ELISA kits for a wide range of species.

IL-27 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL-27 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (4)
Cat. No. ABIN566973
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN388443
Quantity 400 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN1043835
Quantity 100 μg
Datasheet Datasheet

Recommended IL-27 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6975390
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6962566
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957119
Quantity 96 tests
Datasheet Datasheet

Recommended IL-27 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1307800
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307802
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320591
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our IL-27 products

Ahmed, Maklad, Khaled, Elyamany: "Interleukin-27 and interleukin-35 in de novo acute myeloid leukemia: expression and significance as biological markers." in: Journal of blood medicine, Vol. 10, pp. 341-349, (2019) (PubMed).

Kumar, Wang, Nielsen: "Adaptive immune responses are altered in adult mice following neonatal hyperoxia." in: Physiological reports, Vol. 6, Issue 2, (2018) (PubMed).

Vultaggio, Nencini, Pratesi, Cammelli, Totaro, Romagnani, Maggi, Matucci: "IL-10-Producing Infliximab-Specific T Cells Regulate the Antidrug T Cell Response in Exposed Patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1283-1289, (2017) (PubMed).

Gao, Pang, Zhang, Li, Tu, Zhang, Niu, Xiong, Xiao, Zhao, Gao, Wang: "Poria Attenuates Idiosyncratic Liver Injury Induced by Polygoni Multiflori Radix Praeparata." in: Frontiers in pharmacology, Vol. 7, pp. 386, (2016) (PubMed).

Di Meo, Airoldi, Sorrentino, Zorzoli, Esposito, Di Carlo: "Interleukin-30 expression in prostate cancer and its draining lymph nodes correlates with advanced grade and stage." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 3, pp. 585-94, (2014) (PubMed).

Morandi, Airoldi, Pistoia: "IL-27 driven upregulation of surface HLA-E expression on monocytes inhibits IFN-? release by autologous NK cells." in: Journal of immunology research, Vol. 2014, pp. 938561, (2014) (PubMed).

Yoshida, Yoshimi, Yoshii, Kim, Dey, Xiong, Munasinghe, Yazawa, ODonovan, Maximova, Sharma, Zhu, Wang, Morse, Ozato: "The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation." in: Immunity, Vol. 40, Issue 2, pp. 187-98, (2014) (PubMed).

Meng, Gong, Fang, Song, Wu, Zhou, Qian: "Effect of interferon-γ on NF-κB and cytokine IL-18 and IL-27 in acute pancreatitis." in: Bosnian journal of basic medical sciences, Vol. 13, Issue 2, pp. 114-8, (2014) (PubMed).

Li, Zhang, Ge, Zhou, Qi, Ma, Xue, Zhou, Yang: "Elevated interleukin-27 enhances the polarization of Th1/Tc1 cells and the production of proinflammatory cytokines in primary immune thrombocytopenia." in: Human immunology, Vol. 73, Issue 3, pp. 240-7, (2012) (PubMed).

Le Texier, Thebault, Carvalho-Gaspar, Vignard, Merieau, Usal, Cuturi, Wood, Chiffoleau: "Immunoregulatory function of IL-27 and TGF-?1 in cardiac allograft transplantation." in: Transplantation, Vol. 94, Issue 3, pp. 226-33, (2012) (PubMed).

Synonyms and alternative names related to IL-27

interleukin 27 (IL27), interleukin 27 (Il27), IL-27, IL-27A, IL-27p28, IL27, IL27A, IL27p28, IL30, Il30, p28, RGD1561420

Protein level used designations for IL-27

  • IL-27 p28 subunit
  • IL-27 subunit alpha
  • IL-27-A
  • IL27-A
  • interleukin 30
  • interleukin-27 subunit alpha
  • interluekin 27
  • interleukin 27
  • interleukin 27 p28 subunit
  • p28
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