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NLR Family, Pyrin Domain Containing 3 (NLRP3) ELISA Kits

NLRP3 encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. Additionally we are shipping NLRP3 Antibodies (196) and NLRP3 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NLRP3 114548 Q96P20
NLRP3 216799 Q8R4B8
Anti-Rat NLRP3 NLRP3 287362  
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Top NLRP3 ELISA Kits at antibodies-online.com

Showing 3 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 9 to 11 Days
$910.56
Details
Mouse 1.56 pg/mL 6.25-400 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Cow 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$1,026.67
Details

Top referenced NLRP3 ELISA Kits

  1. Human NLRP3 ELISA Kit for Sandwich ELISA - ABIN857854 : Piippo, Korkmaz, Hytti, Kinnunen, Salminen, Atalay, Kaarniranta, Kauppinen: Decline in cellular clearance systems induces inflammasome signaling in human ARPE-19 cells. in Biochimica et biophysica acta 2014 (PubMed)

  2. Mouse (Murine) NLRP3 ELISA Kit for Sandwich ELISA - ABIN818941 : Kleiner, Celsi, Tricarico, Zacchigna, Crovella, Marcuzzi: Systemic and neuronal inflammatory markers in a mouse model of mevalonate kinase deficiency: a strain-comparative study. in In vivo (Athens, Greece) 2013 (PubMed)

More ELISA Kits for NLRP3 Interaction Partners

Human NLR Family, Pyrin Domain Containing 3 (NLRP3) interaction partners

  1. NLRP3 (rs4612666) single-nucleotide polymorphisms with ageing and/or smoking habit potentially might play a significant role in the pathogenic pathways of periodontal disease.

  2. Levels of NLRP3 and IL1beta (show IL1B ELISA Kits) were positively correlated with adipocyte diameter in male, but not in female cancer patients.

  3. High expression of NLRP3, NLRC4 (show NLRC4 ELISA Kits), and CASP1 (show CASP1 ELISA Kits) in background non-tumorous liver is significantly correlated with poor prognosis of patients after resection of hepatocellular carcinoma.

  4. identical amino acid substitutions related to NLRP3 mutations are known to be sometimes associated with different phenotype suggesting the involvement of additional genetic and environmental factors

  5. Results indicate that NLRP3 inflammasome plays a vital role in regulating the proliferation and migration of A549 lung cancer cells.

  6. Our findings for the first time show that the NLRP3 rs10754558 polymorphism is involved in the occurrence of CAD (show CAD ELISA Kits) in the Chinese Han population; and G allele can effectively predict clinical outcome of CAD (show CAD ELISA Kits). The G allele susceptibility to CAD (show CAD ELISA Kits) is maybe associated with the increased level of serum IL-1b (show IL1B ELISA Kits).

  7. We now show that ADAM10 (show ADAM10 ELISA Kits) is critical for alpha-hemolysin (show PLC ELISA Kits)-mediated activation of the NLRP3 inflammasome in human monocytes as siRNA knockdown or chemical blockade of ADAM10 (show ADAM10 ELISA Kits)-alpha-hemolysin (show PLC ELISA Kits) interaction leads to diminished inflammasome activation and cell death by reducing the available ADAM10 (show ADAM10 ELISA Kits) on the cell surface.

  8. There is a significant association between rs3806268 in NLRP3 gene and the risk of primary gout in a Chinese population.

  9. the NLRP3 inflammasome is dysregulated in idiopathic pulmonary fibrosis but not in rheumatoid arthritis-usual interstitial pneumonia

  10. The NLRP3 rs3806265 T allele was significantly more frequent in the patients with RAS than in the healthy controls.

Mouse (Murine) NLR Family, Pyrin Domain Containing 3 (NLRP3) interaction partners

  1. Ambient fine particulate matter-induced myocarditis is mediated by EGFR/Akt signaling and overexpression of NLRP3 and NLRP12.

  2. Hepatic NLRP3 inflammasome activation played an important role in the development of non-alcoholic fatty liver disease via relA (show NFkBP65 ELISA Kits) phosphorylation.

  3. NMDAR1 (show GRIN1 ELISA Kits) plays a pivotal role in hemin-induced NLRP3-mediated inflammatory damage through synergistic activation.

  4. Renal medullary Nlrp3 inflammasomes regulate renal medullary blood flow and sodium excretion.

  5. our study demonstrated that ablating the NLRP3 gene significantly reduced neuroinflammation and delayed RGC loss after optic nerve crush injury.

  6. Data show that NLR family pyrin domain containing 3 (Nlrp3) gene silencing abolished the visfatin (show NAMPT ELISA Kits)-induced high mobility group box (show SSRP1 ELISA Kits) protein 1 (HMGB1 (show HMGB1 ELISA Kits)) release from vascular endothelial cell (MVEC).

  7. Sertoli cells have a functional NALP3 inflammasome that modulates NOD1 (show NOD1 ELISA Kits) and pro-IL-1beta (show IL1B ELISA Kits) expression, while NOD2 (show NOD2 ELISA Kits) inversely promoted IL-1beta (show IL1B ELISA Kits) expression.

  8. Melatonin also attenuated the expressions of NLRP3, apoptosis-associated speck-like protein containing a caspase (show CASP3 ELISA Kits) recruitment domain (ASC (show STS ELISA Kits)), cleaved caspase-1 (show CASP1 ELISA Kits), interleukin-1beta (IL-1beta (show IL1B ELISA Kits)), and interleukin-6 (IL-6 (show IL6 ELISA Kits)); these changes were also associated with an increase in the anti-apoptotic factor (Bcl2 (show BCL2 ELISA Kits)) and reduction in the pro-apoptotic factor (Bim (show BCL2L11 ELISA Kits)).

  9. Poly-ADP-ribosylation-mediated degradation of ARTD1 (show PARP1 ELISA Kits) by the NLRP3 inflammasome is a prerequisite for osteoclast maturation.

  10. provides a direct link between miR-7 (show LILRB1 ELISA Kits) and NLRP3 inflammasome-mediated neuroinflammation in the pathogenesis of Parkinson's disease

NLRP3 Antigen Profile

Antigen Summary

This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.

Gene names and symbols associated with NLRP3

  • NLR family, pyrin domain containing 3 (NLRP3) antibody
  • NLR family, pyrin domain containing 3 (LOC100351623) antibody
  • NLR family, pyrin domain containing 3 (nlrp3) antibody
  • NLR family, pyrin domain containing 3 (Nlrp3) antibody
  • AGTAVPRL antibody
  • AII antibody
  • AII/AVP antibody
  • AVP antibody
  • C1orf7 antibody
  • Cias1 antibody
  • CLR1.1 antibody
  • FCAS antibody
  • FCU antibody
  • Mmig1 antibody
  • MWS antibody
  • NALP3 antibody
  • Pypaf1 antibody

Protein level used designations for NLRP3

NACHT, LRR and PYD domains-containing protein 3 , cold autoinflammatory syndrome 1 , cryopyrin , NLR family, pyrin domain containing 3 , NACHT, LRR and PYD domains-containing protein 3-like , NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3 , NACHT, LRR and PYD containing protein 3 , PYRIN-containing APAF1-like protein 1 , caterpiller protein 1.1 , cold autoinflammatory syndrome 1 protein , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 , NACHT/LRR/pyrin domain-containing protein 3 , cold autoinflammatory syndrome 1 homolog , cold autoinflammatory syndrome 1 protein homolog , mast cell maturation inducible protein 1 , mast cell maturation-associated-inducible protein 1 , NLR family pyrin domain containing 3

GENE ID SPECIES
423021 Gallus gallus
469743 Pan troglodytes
490576 Canis lupus familiaris
100351623 Oryctolagus cuniculus
100381165 Xenopus laevis
100392399 Callithrix jacchus
114548 Homo sapiens
216799 Mus musculus
538639 Bos taurus
287362 Rattus norvegicus
701278 Macaca mulatta
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