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NLR Family, Pyrin Domain Containing 3 (NLRP3) ELISA Kits

NLRP3 encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. Additionally we are shipping NLRP3 Antibodies (167) and NLRP3 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NLRP3 114548 Q96P20
NLRP3 216799 Q8R4B8
Anti-Rat NLRP3 NLRP3 287362  
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Top NLRP3 ELISA Kits at

Showing 3 out of 6 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.039 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 9 to 11 Days
Mouse 1.56 pg/ml 6.25-400 pg/mL 96 Tests Log in to see 11 to 13 Days
Cow 3.9 pg/ml 15.6-1000 pg/mL 96 Tests Log in to see 11 to 13 Days

Top referenced NLRP3 ELISA Kits

  1. Human NLRP3 ELISA Kit for Sandwich ELISA - ABIN857854 : Piippo, Korkmaz, Hytti, Kinnunen, Salminen, Atalay, Kaarniranta, Kauppinen: Decline in cellular clearance systems induces inflammasome signaling in human ARPE-19 cells. in Biochimica et biophysica acta 2014 (PubMed)

  2. Mouse (Murine) NLRP3 ELISA Kit for Sandwich ELISA - ABIN818941 : Kleiner, Celsi, Tricarico, Zacchigna, Crovella, Marcuzzi: Systemic and neuronal inflammatory markers in a mouse model of mevalonate kinase deficiency: a strain-comparative study. in In vivo (Athens, Greece) 2013 (PubMed)

More ELISA Kits for NLRP3 Interaction Partners

Human NLR Family, Pyrin Domain Containing 3 (NLRP3) interaction partners

  1. NLRP3 gene rs10754558 polymorphisms are associated with increased risk of metabolic syndrome

  2. Findings suggest that immune-activation in the frontal cortex may occur both in patients with bipolar disorderand schizophrenia, while complex I dysfunction and NLRP3-inflammasome activation may be more specific to bipolar disorder

  3. we found no significant association between NALP3 gene polymorphisms and the risk of primary gout.

  4. NLRP3 inflammasome in subcutaneous adipose tissue may have a role in atherogenesis

  5. NLRP3 polymorphism may have a role in diabetic macrovascular complications, especially in myocardial infarction

  6. NLRP3 expression, and not the inflammasome activation, is required for epithelial-mesenchymal transition in colorectal cancer cells.

  7. These results demonstrated that the close relationship between the expression of NLRP3 signaling pathway and human carotid atherosclerotic plaques.

  8. role of the influenza virus NS1 (show PTPN11 ELISA Kits) protein in activating the NLRP3 inflammasome

  9. NALP3 inflammasome is expressed in the inflammatory periapical tissues. This cytokine-signalling pathway may therefore be crucial in the regulatory control of inflammatory responses in periapical tissues and the development of periapical lesions

  10. PPARgamma (show PPARG ELISA Kits) prevented NALP3 inflammasome formation and IL1beta (show IL1B ELISA Kits) production in HK2 (show HK2 ELISA Kits) cells stimulated by monosodium urate crystals

Mouse (Murine) NLR Family, Pyrin Domain Containing 3 (NLRP3) interaction partners

  1. enhanced ERK (show EPHB2 ELISA Kits) signaling in Drp1 (show CRMP1 ELISA Kits)-knockdown macrophages is implicated in the potentiation of NLRP3 inflammasome activation, via mediating mitochondrial localization of NLRP3 to facilitate the assembly of NLRP3 inflammasome

  2. studies have uncovered the combined actions of the NLRP3 inflammasome and caspase 8 leading to IL-1beta maturation and the directionality of IL-1beta in driving disease inPstpip2(cmo)mice.

  3. The data reveal that Nlrp3 inflammasome-dependent IL-1beta (show IL1B ELISA Kits), associated with localized neutrophil recruitment, plays a crucial role in the development of a nonhealing form of cutaneous leishmaniasis in conventionally resistant mice.

  4. Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 (show IL10 ELISA Kits) Mediated Regulation of NLRP3 Expression and Caspase-8 (show CASP8 ELISA Kits) Activation

  5. While both contributing to pathogen clearance, NLRP3 more than NLRC4 (show NLRC4 ELISA Kits) contributes to deleterious inflammatory responses in cystic fibrosis (show S100A8 ELISA Kits) and correlates with defective NLRC4 (show NLRC4 ELISA Kits)-dependent IL-1Ra (show IL1RN ELISA Kits) production.

  6. The pro-inflammatory and cancer-promoting effects of a high cholesterol diet are mediated by the activation of NLRP3.

  7. Results suggest that astroglial NLRP3 inflammasome complexes are critically involved in neuroinflammation in amyotrophic lateral sclerosis

  8. that generation of reactive oxygen species and potassium efflux contribute to HIV-induced pyroptosis and NLRP3 inflammasome activation in podocytes

  9. Data (including data from studies in knockout mice) suggest NLRP3 is not required for activation of macrophages and dendritic cells by soluble saponin adjuvant, QS-21, in mice immunized with HIV-1 glycoprotein 120 subunit vaccine.

  10. Rotavirus infection in macrophages depend on MAVS (show MAVS ELISA Kits) but not involve the NLRP3 inflammasome nor JNK (show MAPK8 ELISA Kits) and p38 (show CRK ELISA Kits) signal pathway.

NLRP3 Antigen Profile

Antigen Summary

This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.

Gene names and symbols associated with NLRP3

  • NLR family, pyrin domain containing 3 (NLRP3) antibody
  • NLR family, pyrin domain containing 3 (LOC100351623) antibody
  • NLR family, pyrin domain containing 3 (nlrp3) antibody
  • NLR family, pyrin domain containing 3 (Nlrp3) antibody
  • AGTAVPRL antibody
  • AII antibody
  • AII/AVP antibody
  • AVP antibody
  • C1orf7 antibody
  • Cias1 antibody
  • CLR1.1 antibody
  • FCAS antibody
  • FCU antibody
  • Mmig1 antibody
  • MWS antibody
  • NALP3 antibody
  • Pypaf1 antibody

Protein level used designations for NLRP3

NACHT, LRR and PYD domains-containing protein 3 , cold autoinflammatory syndrome 1 , cryopyrin , NLR family, pyrin domain containing 3 , NACHT, LRR and PYD domains-containing protein 3-like , NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3 , NACHT, LRR and PYD containing protein 3 , PYRIN-containing APAF1-like protein 1 , caterpiller protein 1.1 , cold autoinflammatory syndrome 1 protein , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 , NACHT/LRR/pyrin domain-containing protein 3 , cold autoinflammatory syndrome 1 homolog , cold autoinflammatory syndrome 1 protein homolog , mast cell maturation inducible protein 1 , mast cell maturation-associated-inducible protein 1 , NLR family pyrin domain containing 3

423021 Gallus gallus
469743 Pan troglodytes
490576 Canis lupus familiaris
100351623 Oryctolagus cuniculus
100381165 Xenopus laevis
100392399 Callithrix jacchus
114548 Homo sapiens
216799 Mus musculus
538639 Bos taurus
287362 Rattus norvegicus
701278 Macaca mulatta
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