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NLR Family, Pyrin Domain Containing 3 (NLRP3) ELISA Kits

NLRP3 encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. Additionally we are shipping NLRP3 Antibodies (201) and NLRP3 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NLRP3 114548 Q96P20
NLRP3 216799 Q8R4B8
Anti-Rat NLRP3 NLRP3 287362  
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Top NLRP3 ELISA Kits at antibodies-online.com

Showing 3 out of 8 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 9 to 11 Days
$910.56
Details
Mouse 1.56 pg/mL 6.25-400 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Cow 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$1,026.67
Details

Top referenced NLRP3 ELISA Kits

  1. Human NLRP3 ELISA Kit for Sandwich ELISA - ABIN857854 : Piippo, Korkmaz, Hytti, Kinnunen, Salminen, Atalay, Kaarniranta, Kauppinen: Decline in cellular clearance systems induces inflammasome signaling in human ARPE-19 cells. in Biochimica et biophysica acta 2014 (PubMed)

  2. Mouse (Murine) NLRP3 ELISA Kit for Sandwich ELISA - ABIN818941 : Kleiner, Celsi, Tricarico, Zacchigna, Crovella, Marcuzzi: Systemic and neuronal inflammatory markers in a mouse model of mevalonate kinase deficiency: a strain-comparative study. in In vivo (Athens, Greece) 2013 (PubMed)

More ELISA Kits for NLRP3 Interaction Partners

Human NLR Family, Pyrin Domain Containing 3 (NLRP3) interaction partners

  1. NLRP3 inflammasome is implicated in the pathogenesis of dermatomyositis and polymyositis.

  2. these data show that NLRP3 is primarily a kidney tubule-expressed protein that decreases in abundance in progressive IgAN.

  3. Studies indicate that NIMA related kinase 7 (NEK7 (show NEK7 ELISA Kits)) targets at NLRP3 protein and involves in the activation of NLRP3 inflammasome.

  4. This study demonstrated that dysregulated expression of NLRP3-caspase-1 (show CASP1 ELISA Kits)-IL-1beta (show IL1B ELISA Kits) axis was observed in patients with MM, suggesting they might be involved in the pathogenesis of MM.

  5. DNA methylation (show HELLS ELISA Kits) was involved in NLRP3 inflammasome activation during Mycobacterium tuberculosis infection and provided a new insight into the relationship between host and pathogens.

  6. The NLRP3/caspase-1 (show CASP1 ELISA Kits)/IL-1beta (show IL1B ELISA Kits) axis is active in cartilaginous endplates of patients with Modic changes and inflammatory cascades can exacerbate the cartilaginous endplate degeneration which may act as a trigger for intervertebral disc degeneration and low back pain.

  7. Authors conclude that Aldo induces renal tubular cell injury via MR dependent, mitochondrial ROS (show ROS1 ELISA Kits)-mediated NLRP3 inflammasome activation.

  8. None of these 15 SNPs in NOD2 (show NOD2 ELISA Kits), CARD8 (show CARD8 ELISA Kits), and NLPR3 genes showed a significant difference.

  9. NLRP3 (rs4612666) single-nucleotide polymorphisms with ageing and/or smoking habit potentially might play a significant role in the pathogenic pathways of periodontal disease.

  10. Levels of NLRP3 and IL1beta (show IL1B ELISA Kits) were positively correlated with adipocyte diameter in male, but not in female cancer patients.

Mouse (Murine) NLR Family, Pyrin Domain Containing 3 (NLRP3) interaction partners

  1. Data show that inhibiting caspase-1 (show CASP1 ELISA Kits) activity in the NLR (show CXCR5 ELISA Kits) family, pyrin domain-containing 3 protein (NLRP3) inflammasome decreased gastric cell apoptosis.

  2. Authors conclude that Aldo induces renal tubular cell injury via MR dependent, mitochondrial ROS (show ROS1 ELISA Kits)-mediated NLRP3 inflammasome activation.

  3. Using genetically modified mice lacking either NLRP3 or multiple downstream inflammasome response elements, we ruled out a role for the NLRP3 inflammasome or any Caspase-1 (show CASP1 ELISA Kits) or -11 dependent inflammasome in regulating RBC (show CACNA1C ELISA Kits) alloantibody production to a model antigen.

  4. Decreased ET-1 (show EDN1 ELISA Kits) levels were associated with greater activation of NLRP3 and IL-1beta (show IL1B ELISA Kits) in normal glucose. High glucose increased NLRP3 markers and activation compared to normal and low glucose

  5. Ambient fine particulate matter-induced myocarditis is mediated by EGFR/Akt signaling and overexpression of NLRP3 and NLRP12.

  6. Hepatic NLRP3 inflammasome activation played an important role in the development of non-alcoholic fatty liver disease via relA (show NFkBP65 ELISA Kits) phosphorylation.

  7. NMDAR1 (show GRIN1 ELISA Kits) plays a pivotal role in hemin-induced NLRP3-mediated inflammatory damage through synergistic activation.

  8. Renal medullary Nlrp3 inflammasomes regulate renal medullary blood flow and sodium excretion.

  9. our study demonstrated that ablating the NLRP3 gene significantly reduced neuroinflammation and delayed RGC loss after optic nerve crush injury.

  10. Data show that NLR family pyrin domain containing 3 (Nlrp3) gene silencing abolished the visfatin (show NAMPT ELISA Kits)-induced high mobility group box (show SSRP1 ELISA Kits) protein 1 (HMGB1 (show HMGB1 ELISA Kits)) release from vascular endothelial cell (MVEC).

NLRP3 Antigen Profile

Antigen Summary

This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.

Gene names and symbols associated with NLRP3

  • NLR family, pyrin domain containing 3 (NLRP3) antibody
  • NLR family, pyrin domain containing 3 (LOC100351623) antibody
  • NLR family, pyrin domain containing 3 (nlrp3) antibody
  • NLR family, pyrin domain containing 3 (Nlrp3) antibody
  • AGTAVPRL antibody
  • AII antibody
  • AII/AVP antibody
  • AVP antibody
  • C1orf7 antibody
  • Cias1 antibody
  • CLR1.1 antibody
  • FCAS antibody
  • FCU antibody
  • Mmig1 antibody
  • MWS antibody
  • NALP3 antibody
  • Pypaf1 antibody

Protein level used designations for NLRP3

NACHT, LRR and PYD domains-containing protein 3 , cold autoinflammatory syndrome 1 , cryopyrin , NLR family, pyrin domain containing 3 , NACHT, LRR and PYD domains-containing protein 3-like , NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3 , NACHT, LRR and PYD containing protein 3 , PYRIN-containing APAF1-like protein 1 , caterpiller protein 1.1 , cold autoinflammatory syndrome 1 protein , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 , NACHT/LRR/pyrin domain-containing protein 3 , cold autoinflammatory syndrome 1 homolog , cold autoinflammatory syndrome 1 protein homolog , mast cell maturation inducible protein 1 , mast cell maturation-associated-inducible protein 1 , NLR family pyrin domain containing 3

GENE ID SPECIES
423021 Gallus gallus
469743 Pan troglodytes
490576 Canis lupus familiaris
100351623 Oryctolagus cuniculus
100381165 Xenopus laevis
100392399 Callithrix jacchus
114548 Homo sapiens
216799 Mus musculus
538639 Bos taurus
287362 Rattus norvegicus
701278 Macaca mulatta
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