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Nucleoporin 98kDa (NUP98) ELISA Kits

Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. Additionally we are shipping Nucleoporin 98kDa Antibodies (56) and Nucleoporin 98kDa Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NUP98 269966  
NUP98 81738 P49793
NUP98 4928 P52948
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96 Tests Log in to see 8 to 9 Days
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More ELISA Kits for Nucleoporin 98kDa Interaction Partners

Fruit Fly (Drosophila melanogaster) Nucleoporin 98kDa (NUP98) interaction partners

  1. Nup98 associates and colocalizes with the MBD (show DPEP1 ELISA Kits)-R2/NSL and Trx (show GSR ELISA Kits) complexes. Nup98 regulates transcription of Trx (show GSR ELISA Kits) targets, the Hox (show MSH2 ELISA Kits) genes.

  2. Nup98, a virus-induced gene, was antiviral against a panel of viruses.

  3. Study analyzed genomic interactions of full-length nucleoporins Nup98, Nup50 (show NUP50 ELISA Kits), and Nup62 and found that they predominantly interacted with active genes inside the nucleoplasm, particularly those involved in developmental regulation and the cell cycle.

  4. Nup88 (show NUP88 ELISA Kits) localizes to silent loci, Sec13 (show SEC13 ELISA Kits), Nup98, and a subset of FG-repeat nucleoporins bind to developmentally regulated genes undergoing transcription induction.

Mouse (Murine) Nucleoporin 98kDa (NUP98) interaction partners

  1. The age-associated accumulation of somatic mutations that occurs in the Nup98-HOXD13 (show HOXD13 ELISA Kits) (NHD13) mouse model of leukemia progression was significantly elevated by co-expression of a PKR (show EIF2AK2 ELISA Kits) transgene.

  2. Nup50 (show NUP50 ELISA Kits) dynamics are independent of importin alpha (show KPNA4 ELISA Kits), Nup153 (show NUP153 ELISA Kits), and Nup98, even though the latter two proteins also exhibit transcription-dependent mobility.

  3. Data indicate that loss of cyclin-dependent kinase inhibitor p15 (p15Ink4b (show CDKN2B ELISA Kits)) collaborates with oncogene (show RAB1A ELISA Kits) fusion protein Nup98-HoxD13 (show HOXD13 ELISA Kits) transgene in the development of predominantly myeloid neoplasms.

  4. Homeobox (show PRRX1 ELISA Kits) partners create more potent NUP98 fusion oncogenes than do non-homeobox (show PRRX1 ELISA Kits) partners.

  5. findings show that expression of NUP98-HOXD13 (show HOXD13 ELISA Kits) impairs class switch recombination and reduces the antibody-mediated immune response, in addition to its role in leukemia

  6. Mice expressing both the FLT3 (show FLT3 ELISA Kits)/ITD and Nup98-HoxD13 (show HOXD13 ELISA Kits) (NHD13) fusion gene developed acute myeloid leukemia (show BCL11A ELISA Kits) with 100% penetrance

  7. Data show that NUP98-HOXA10HD, a novel, canonical NUP98-Hox (show MSH2 ELISA Kits) fusion, significantly enhances the self-renewal capacity of hematopoietic stem cells.

  8. These results clearly demonstrate that Nup98 functions as a novel shuttling cofactor for Crm1 (show XPO1 ELISA Kits)-mediated nuclear export in conjunction with RanBP3 (show RANBP3 ELISA Kits).

  9. A mouse model of CML blast crisis induced by cooperation between BCR/ABL (show ABL1 ELISA Kits) and NUP98/HOXA9 (show HOXA9 ELISA Kits)

  10. results suggest that Rae1 (show RAE1 ELISA Kits) and Nup98 are temporal regulators of APC (show APC ELISA Kits)(Cdh1 (show CDH1 ELISA Kits)) that maintain euploidy by preventing unscheduled degradation of securin (show PTTG1 ELISA Kits)

Zebrafish Nucleoporin 98kDa (NUP98) interaction partners

  1. data show that a novel nup98 was identified and it serves a role in nucleocytoplasmic trafficking similar to human NUP98.

Human Nucleoporin 98kDa (NUP98) interaction partners

  1. Despite the difference in localization, all tested Nup98 chimera provoked morphological alterations in the nuclear envelope (NE), in particular affecting the nuclear lamina and the lamina-associated polypeptide 2alpha.

  2. NUP98-HOXA9 (show HOXA9 ELISA Kits) expression induces myeloid disease.

  3. Overall, these results demonstrate a novel role for FOXK1 (show FOXK2 ELISA Kits) in regulating the expression of antiviral genes via Nup98, from insects to humans.

  4. deregulation of the retinoid/rexinoid signaling pathway has a major role and may represent a potential therapeutic target for NUP98-RARG (show RARG ELISA Kits)-mediated transformation

  5. Acute myeloid leukemia (show BCL11A ELISA Kits) can be reproduced in mice by transducing mouse mesenchymal stem cells with the human NUP98-NSD1 (show NSD1 ELISA Kits) fusion and the FLT3 (show FLT3 ELISA Kits)-ITD mutated constracts.

  6. These data reveal an emergent Kap (show CDKN3 ELISA Kits)-centric barrier mechanism that may underlie mechanistic and kinetic control in the nuclear pore complex.

  7. Vesiculoviral matrix (M) protein (show MYOM2 ELISA Kits) occupies nucleic acid binding site at nucleoporin (show AGFG2 ELISA Kits) pair (Rae1 (show RAE1 ELISA Kits) * Nup98).

  8. NUP98 oncoproteins predispose myeloid cells to oncogenic transformation or malignant progression by promoting whole chromosome instability.

  9. NUP98/JARID1A (show KDM5A ELISA Kits) is a novel recurrent genetic abnormality in pediatric AMKL (show MKL1 ELISA Kits)

  10. Data indicate increased levels of reactive oxygen species (ROS (show ROS1 ELISA Kits)) were detected in bone marrow nucleated cells (BMNC) that express CD71 (show TFRC ELISA Kits) in in NUP98-HOXD13 (show HOXD13 ELISA Kits) (NHD13) transgenic mice, a murine model for myelodysplastic syndromes (MDS (show PAFAH1B1 ELISA Kits)).

Xenopus laevis Nucleoporin 98kDa (NUP98) interaction partners

  1. These data support a model in which Nup98 interacts with microtubules and antagonizes MCAK (show KIF2C ELISA Kits) activity, thus promoting bipolar spindle assembly.

Nucleoporin 98kDa (NUP98) Antigen Profile

Antigen Summary

Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described.

Gene names and symbols associated with Nucleoporin 98kDa (NUP98) ELISA Kits

  • Nucleoporin 98-96 (Nup98-96) antibody
  • nucleoporin 98kDa (Nup98) antibody
  • nucleoporin 98kDa (NUP98) antibody
  • nucleoporin 98 (Nup98) antibody
  • nucleoporin 98 (nup98) antibody
  • Nup98 protein (nup98) antibody
  • 4732457F17 antibody
  • ADIR2 antibody
  • AI849286 antibody
  • CG10198 antibody
  • CG10201 antibody
  • Dmel\\CG10198 antibody
  • GB12688 antibody
  • im:7151238 antibody
  • l(3)95BCd antibody
  • Nup-98 antibody
  • Nup 96 antibody
  • NUP96 antibody
  • NUP98 antibody
  • Nup 98 antibody
  • nup98-96 antibody
  • Nup98-Nup96 antibody
  • Nup98/96 antibody
  • nup145 antibody
  • NUP196 antibody
  • zgc:63593 antibody
  • zgc:113968 antibody

Protein level used designations for Nucleoporin 98kDa (NUP98) ELISA Kits

CG10198-PA , CG10198-PC , CG10198-PD , Nup98 , Nup98-96-PA , Nup98-96-PC , Nup98-96-PD , nucleoporin 98 , nucleoporin 98-96 , nucleoporin98-96 , nucleoporin 98kD , nucleoporin 98kDa , nuclear pore complex protein Nup98-Nup96-like , nuclear pore complex protein Nup98-Nup96 , 98 kDa nucleoporin , nuclear pore complex protein Nup98 , nucleoporin Nup98 , GLFG-repeat containing nucleoporin , Nup98-Nup96

42816 Drosophila melanogaster
408335 Apis mellifera
450971 Pan troglodytes
587580 Strongylocentrotus purpuratus
100016427 Monodelphis domestica
100052986 Equus caballus
100090367 Ornithorhynchus anatinus
100414799 Callithrix jacchus
100475098 Ailuropoda melanoleuca
100522560 Sus scrofa
269966 Mus musculus
81738 Rattus norvegicus
777756 Danio rerio
430616 Gallus gallus
4928 Homo sapiens
476822 Canis lupus familiaris
540004 Bos taurus
100343626 Oryctolagus cuniculus
446233 Xenopus laevis
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