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OCLN encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Additionally we are shipping Occludin Antibodies (111) and Occludin Proteins (9) and many more products for this protein.
Showing 10 out of 42 products:
Human Occludin ELISA Kit for Sandwich ELISA - ABIN417945
Xu, Feng, Xie, Zhang, Wu, Xu: HIV-1 Tat protein increases the permeability of brain endothelial cells by both inhibiting occludin expression and cleaving occludin via matrix metalloproteinase-9. in Brain research 2012
Show all 2 references for ABIN417945
Mouse (Murine) Occludin ELISA Kit for Sandwich ELISA - ABIN425437
Summa, Voigt, Forsyth, Shaikh, Cavanaugh, Tang, Vitaterna, Song, Turek, Keshavarzian: Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation. in PLoS ONE 2013
Show all 2 references for ABIN425437
This is report of a family of Indian origin with two affected sibs and segregation of a homozygous novel OCLN mutation in the exon 3(NG_028291.1(OCLN_v001):c.252delC).
Data show that estrogen mediates control of hepatitis C virus through the G-protein-coupled estrogen receptor (show ESR1 ELISA Kits) 30 (GPR30 (show GPER ELISA Kits)) pathway leading to cleavage of occludin by Matrix Metalloproteinase-9 (MMP-9 (show MMP9 ELISA Kits)).
In hepatitis C virus -infected human livers, occludin and ADRP (show PLIN2 ELISA Kits) mRNA expression levels correlated with each other. Hepatitis C virus increases occludin expression via the upregulation of ADRP (show PLIN2 ELISA Kits).
Data show that claudin-6 (CLDN6 (show CLDN6 ELISA Kits)) R209Q and occludin (OCLN) P24A mutations do not affect HCV pseudoparticles (HCVpp) entry.
resistance to HCV in HIV+ patients may be related to genetic variation in SCARB1 (show SCARB1 ELISA Kits) or OCLN
Angiopoietin-1 (show ANGPT1 ELISA Kits) Regulates Brain Endothelial Permeability through PTPN-2 (show PTPN2 ELISA Kits) Mediated Tyrosine Dephosphorylation of Occludin
TIMP1 (show TIMP1 ELISA Kits) downregulates MMP-2 (show MMP2 ELISA Kits) activity and inhibits the degradation of occluding in Caco-2 intestinal cells
Study uncovers a novel antiviral effect of miR (show MLXIP ELISA Kits)-122 on human liver cells and shows that over-expression of miR (show MLXIP ELISA Kits)-122 can decrease HCV entry into hepatocytes through down-regulation of OCLN.
Lipid raft-associated processes, such as PP2A (show PPP2R4 ELISA Kits) and MMP-2 (show MMP2 ELISA Kits) activation, participate in PCB153-induced disruption of occludin function in brain endothelial barrier.
miR (show MLXIP ELISA Kits)-18a and RUNX1 (show RUNX1 ELISA Kits) could reversely regulate the permeability of blood-tumor barrier as well as the expressions and distributions of ZO-1 (show TJP1 ELISA Kits), occludin and claudin-5 (show CLDN5 ELISA Kits).
ADMA has potent adverse effects on cell proliferation, intracellular ROS (show ROS1 ELISA Kits) generation, cell permeability, levels of ICAM-1 (show ICAM1 ELISA Kits), and the tight-junction protein occludin
the presence of occludin at the membrane is dependent in part on calcium-sensitive signaling cascades
cyclic strain modulates both the expression and phosphorylation state of occludin and ZO-1 (show TJP1 ELISA Kits) in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity
These data demonstrate a novel mechanism of VEGF (show VEGFA ELISA Kits)-induced occludin phosphorylation and ubiquitination that contributes to TJ trafficking and subsequent vascular permeability.
Tricellulin (show MARVELD2 ELISA Kits) is a specific redox sensor and sealing element at 3-cell contacts and may compensate as a redox mediator for occludin loss at 2-cell contacts in vivo and in vitro.
These findings provide evidence for occludin playing a role in the invasion of Toxoplasma gondii in small intestinal epithelial cells.
occludin deficiency increases susceptibility to ethanol-induced colonic mucosal barrier dysfunction and liver damage in mice.
PHD3 (show EGLN3 ELISA Kits) protects intestinal epithelial barrier function and reveal a hydroxylase-independent function of PHD3 (show EGLN3 ELISA Kits) in stabilizing occludin
Zonula occludens-1 (show TJP1 ELISA Kits), occludin and E-cadherin (show CDH1 ELISA Kits) expression and organization in salivary glands
Our study demonstrates spatiotemporal alterations in occludin mRNA- and protein-expression, indicating that Cx43 (show GJA1 ELISA Kits) might act as a regulator for blood-testis-barrier
Occludin and Claudin-1 (show CLDN1 ELISA Kits) expressions in the large intestine are under the circadian control, which is associated with temporal regulation of colonic permeability and also susceptibility to colitis.
Hypoxic induction of CAV1 (show CAV1 ELISA Kits) in the colon was essential for intestinal barrier integrity by regulating occludin expression.
Activation of RhoA (show RHOA ELISA Kits)/ROCK1 (show ROCK1 ELISA Kits) by high glucose in diabetic nephropathy disrupts the expression and translocation of occludin/ZO-1 (show TJP1 ELISA Kits), which can be corrected by simvastatin.
Similar levels of occludin gene expression were detected.
ZO-1 (show TJP1 ELISA Kits) and occludin are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin at the blastocyst stage.
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
, tight junction protein occludin TM4 minus
, thiopurine methyltransferase
, tight junction protein occludin
, tight-junction protein
, occludin b