You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Sirtuin 6 (SIRT6) Antibodies

SIRT6 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Additionally we are shipping Sirtuin 6 Proteins (24) and Sirtuin 6 Kits (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SIRT6 51548 Q8N6T7
SIRT6 50721 P59941
SIRT6 299638  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online

Top anti-Sirtuin 6 Antibodies at

Showing 10 out of 164 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated EIA, IHC (p) 0.4 mL Log in to see 6 to 8 Days
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SIRT6 Antibody Titration: 1.25ug/mlPositive Control:... 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with ... Western blot analysis of SIRT6 Antibody (C-term) (ABIN390181) in mouse... 400 μL Log in to see 10 to 11 Days
Human Chicken Un-conjugated EIA, WB Western blot analysis of SIRT6 in HeLa cell lysate with SIRT6 antibody... 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB SIRT6 antibody tested by Western blot. HeLa cells nuclear extract (25 ... 100 μL Log in to see 1 to 2 Days
Human Mouse Un-conjugated IF, WB Anti-SIRT6 mouse monoclonal antibody (ABIN2455114) immunofluorescent s... HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane... 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB SIRT6 Antibody (C-term) (ABIN657945) western blot analysis in K562 cel... 400 μL Log in to see 10 to 11 Days
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged SIRT6 is 1 ng/ml as a captu... 100 μg Log in to see 9 Days

SIRT6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, ,
, , , , , , , , , , , , , , , , ,
Mouse (Murine) , ,

, , , , , ,
Rat (Rattus) , ,

, ,

Top referenced anti-Sirtuin 6 Antibodies

  1. Cow (Bovine) Polyclonal SIRT6 Primary Antibody for WB - ABIN2779624 : Wajapeyee, Malonia, Palakurthy, Green: Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors. in Genes & development 2013 (PubMed)
    Show all 2 references for ABIN2779624

  2. Human Monoclonal SIRT6 Primary Antibody for ELISA - ABIN526804 : Grimley, Polyakova, Vamathevan, McKenary, Hayes, Patel, Smith, Bridges, Fosberry, Bhardwaja, Mouzon, Chung, Barrett, Richmond, Modha, Solari: Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NF?B responses. in PLoS ONE 2012 (PubMed)
    Show all 2 references for ABIN526804

  3. Human Polyclonal SIRT6 Primary Antibody for IHC (p), WB - ABIN390181 : Wu, Liu, Fu, Liu, Zhou: Direct evidence of sirtuin downregulation in the liver of non-alcoholic fatty liver disease patients. in Annals of clinical and laboratory science 2014 (PubMed)
    Show all 2 references for ABIN390181

  4. Human Polyclonal SIRT6 Primary Antibody for EIA, WB - ABIN783616 : Salminen, Kaarniranta: SIRT1: regulation of longevity via autophagy. in Cellular signalling 2009 (PubMed)
    Show all 2 references for ABIN783616

  5. Human Polyclonal SIRT6 Primary Antibody for EIA, IHC (p) - ABIN358735 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Show all 2 references for ABIN358735

  6. Chicken Polyclonal SIRT6 Primary Antibody for WB - ABIN2779625 : Frye: Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. in Biochemical and biophysical research communications 2000 (PubMed)

  7. Human Polyclonal SIRT6 Primary Antibody for WB - ABIN2668661 : Rajendran, Kidane, Yu, Dashwood, Bisson, Löhr, Ho, Williams, Dashwood: HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates. in Epigenetics 2013 (PubMed)

  8. Human Polyclonal SIRT6 Primary Antibody for IHC (p), WB - ABIN712483 : Thirumurthi, Shen, Xia, LaBaff, Wei, Li, Chang, Chen, Lin, Yu, Hung: MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer. in Science signaling 2014 (PubMed)

More Antibodies against Sirtuin 6 Interaction Partners

Human Sirtuin 6 (SIRT6) interaction partners

  1. Lamin A (show LMNA Antibodies) promotes SIRT6-dependent DNA-PKcs (DNA-PK catalytic subunit (show PRKDC Antibodies)) recruitment to chromatin.

  2. demonstrate that PKM2 deacetylation is integral to SIRT6-mediated tumor suppression and inhibition of metastasis. Additionally, reduced SIRT6 levels correlate with elevated nuclear acetylated PKM2 levels in increasing grades of hepatocellular carcinoma

  3. SIRT6 mutations identified in human cancers alter either SIRT6 stability, localization, or enzymatic activity. Deacetylase, not demyristoylase, activity is critical for SIRT6 tumor-suppressor.

  4. These findings therefore provide insights into the functional interplay between SIRT6 and DNA repair mechanisms, with implications for both tumorigenesis and the treatment of multiple myeloma.

  5. These results support a hypothesis whereby RUNX2 (show RUNX2 Antibodies)-mediated repression of the SIRT6 tumor suppressor regulates metabolic pathways that promote breast cancer progression

  6. EGF (show EGF Antibodies) stimulates loss of FOXO3 (show FOXO3 Antibodies)/SIRT6, which is blockaded by the inhibition of upstream pathways as well as lipid synthesis, revealing existence of a negative regulatory loop between LDs and FOXO3 (show FOXO3 Antibodies)/SIRT6.

  7. associations between SIRT6 rs107251 and pulse wave velocity, as well as an interaction between SIRT6 rs107251 and soybean intake for different levels of pulse wave velocity were found.

  8. review describes the protective effects of SIRT1 (show SIRT1 Antibodies) and SIRT6 against COPD (show ARCN1 Antibodies) and their target proteins involved in the pathophysiology of COPD (show ARCN1 Antibodies).

  9. Indicate a novel oncogenic role of E2F1 (show E2F1 Antibodies) by enhancing glycolysis via suppression Sirt6 transcription in bladder and prostate tumor cell lines.

  10. ITCH modulates SIRT6 and SREBP2 (show SREBF2 Antibodies) to influence lipid metabolism and atherosclerosis in ApoE (show APOE Antibodies) null mice

Cow (Bovine) Sirtuin 6 (SIRT6) interaction partners

  1. results suggest that some polymorphisms in SIRT6 are associated with production traits and may be used as candidates for marker-assisted selection (MAS (show MAS1 Antibodies)) and management in beef cattle breeding programs.

Mouse (Murine) Sirtuin 6 (SIRT6) interaction partners

  1. Sirt6 depletion causes spindle defects and chromosome misalignment during meiosis of mouse oocyte

  2. In SIRT6-deficient mice there is impaired bone remodeling leading to osteopenia.

  3. SIRT6/NF-kappaB (show NFKB1 Antibodies) signaling axis in ginsenoside Rg1 (show PPP1R3A Antibodies)-delayed hematopoietic stem/progenitor cell senescence.

  4. Data showed the expression levels of SIRT1 (show SIRT1 Antibodies), SIRT3 (show SIRT3 Antibodies), and SIRT6 were decreased in the ovaries of aged mice and mice treated with chemotherapy, but increased in mice treated to caloric restriction suggesting these genes are closely related to ovarian reserve.

  5. Sodium sulfide (show SQRDL Antibodies) protected brain endothelial cells against simulated ischemic injury through SIRT6-dependent mechanisms.

  6. SIRT1 (show SIRT1 Antibodies) localizes to the promoters of several aberrantly silenced tumor suppressor genes whose DNA is hypermethylated

  7. Sirt6 has key roles in the relationship among ageing, metabolic syndrome, and osteoarthritis

  8. Overall these results suggest that SIRT6 may play a role in synaptic function and neuronal maturation and

  9. Studied the effect of icariin (ICA) on cardiac aging through its effects on the SIRT6 enzyme and on the NF-kappaB (show NFKB1 Antibodies) pathway.

  10. Our results identify SIRT6 as a critical modulator of retinal function, likely through its effects on chromatin.

Sirtuin 6 (SIRT6) Antigen Profile

Protein Summary

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Sirtuin 6 (SIRT6) Antibodies

  • sirtuin 6 (sirt6) antibody
  • sirtuin 6 (SIRT6) antibody
  • sirtuin 6 (Sirt6) antibody
  • 2810449N18Rik antibody
  • AI043036 antibody
  • Sir2l6 antibody

Protein level used designations for anti-Sirtuin 6 (SIRT6) Antibodies

sirtuin (silent mating type information regulation 2 homolog) 6 , NAD-dependent deacetylase sirtuin-6 , NAD-dependent protein deacetylase sirtuin-6 , SIR2-like protein 6 , regulatory protein SIR2 homolog 6 , sir2-related protein type 6 , sirtuin type 6

444018 Xenopus laevis
428332 Gallus gallus
51548 Homo sapiens
485045 Canis lupus familiaris
100126274 Sus scrofa
535416 Bos taurus
50721 Mus musculus
299638 Rattus norvegicus
Selected quality suppliers for anti-Sirtuin 6 (SIRT6) Antibodies
Did you look for something else?