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Tenascin C Proteins (TNC)

TNC encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. Additionally we are shipping Tenascin C Antibodies (287) and Tenascin C Kits (52) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNC 3371 P24821
Mouse TNC TNC 21923 Q80YX1
TNC 116640  
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Top Tenascin C Proteins at

Showing 7 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
HOST_Human Human Un-conjugated   0.1 mg Log in to see 2 to 3 Days
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 16 Days

TNC Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Rat (Rattus)

More Proteins for Tenascin C (TNC) Interaction Partners

Horse (Equine) Tenascin C (TNC) interaction partners

  1. Results suggest that sequence variants in TNC and COL5A1 genes are associated with superficial digital flexor tendinopathy in TB racehorses. In

Human Tenascin C (TNC) interaction partners

  1. High TNC expression is associated with retinoblastoma.

  2. prepartum and postpartum TN-C serum levels significantly higher in mild and severe preeclampsia than in healthy pregnancy

  3. Tenascin-C overexpression in cancer cells and stromal fibroblasts was an independent poor prognostic factor for overall survival and disease-free survival esophageal squamous cell carcinoma patients.

  4. Serum TNC levels are significantly raised and correlate with various clinical and laboratory variables of disease activity in children with enthesitis-related arthritis

  5. This study has identified tenascin-C as a promoter of the invasiveness of brain tumor-initiating cells through a mechanism involving ADAM-9 (show ADAM9 Proteins) proteolysis via the c-Jun NH2-terminal kinase (show MAPK8 Proteins) pathway.

  6. Co-expression of Matrix metalloproteinase-9 (show MMP9 Proteins) and Tenascin-C was associated with poorer prognosis and was found to be an independent predictor of survival

  7. Studied the expression of TNC in tissue microarrays including 17 GBMs, 18 WHO grade III astrocytomas, 15 WHO grade II astrocytomas, 4 WHO grade I astrocytomas, and 7 normal brain tissue samples by immunohistochemical staining.

  8. No difference in tenascin-C expression was found in COPD (show ARCN1 Proteins).

  9. miR (show MLXIP Proteins)-133a enhances the protective capacity of cardiac progenitors cells after myocardial infarction

  10. A pivotal role for TNC in tuning the local immune response to establish equilibrium between disseminated nodal cancer stem cells and the immune system.

Mouse (Murine) Tenascin C (TNC) interaction partners

  1. Tenascin-C may be an important mediator in the development of brain edema and blood-brain barrier disruption following subarachnoid hemorrhage, mechanisms for which may involve MAPK (show MAPK1 Proteins)-mediated MMP-9 (show MMP9 Proteins) induction and ZO-1 (show TJP1 Proteins) degradation

  2. TN-C aggravates autoimmune myocarditis by driving the dendritic cell activation and Th17 differentiation via toll-like receptor 4 (show TLR4 Proteins).

  3. TNC supports the stress-induced expression of extracellular matrix that reinforce the aorta and the stress-induced excessive inflammatory response in the aorta.

  4. TNC plays an important role in TMJ wound healing, especially for wounds generated by mechanical stress.

  5. Tenascin-C is required for normal Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling in the whisker follicle stem cell niche.

  6. TNC downregulates Dickkopf-1 (DKK1 (show DKK1 Proteins)) promoter activity through the blocking of actin stress fiber formation, activates Wnt (show WNT2 Proteins) signaling, and induces Wnt (show WNT2 Proteins) target genes in tumor and endothelial cells.

  7. The increased levels of elastin (show ELN Proteins), type V collagen and tenascin C are probably the result of increased expression by fibroblastic cells; reversely, elastin (show ELN Proteins) influences myofibroblast differentiation

  8. Elevated tenascin-C expression in globoid cell leukodystrophy modified microglial functional response to psychosine.

  9. Tenascin-C-derived peptide TNIIIA2 highly enhances cell survival and platelet-derived growth factor (PDGF (show PDGFA Proteins))-dependent cell proliferation through potentiated and sustained activation of integrin alpha5beta1.

  10. FHL2 (show FHL2 Proteins)-deficient mice developed a severe and long-lasting lung pathology due to enhanced expression of tenascin C and impaired activation of inflammation-resolving macrophages.

Pig (Porcine) Tenascin C (TNC) interaction partners

  1. TNC does not appear to contribute directly to outflow resistance in the eye.

  2. TNC could be a potential candidate gene for meat quality traits in pigs.

  3. tenascin binds to fibronectin (show FN1 Proteins) at a cryptic binding site

Zebrafish Tenascin C (TNC) interaction partners

  1. Reloading of atrophied rat soleus muscle induces tenascin-C expression around damaged muscle fibers. Increase of rat soleus muscle loading modifies basement membrane of damaged muscle fibers through ectopic endomysial expression of tenascin-C.

  2. tenascin-C is part of a specialized extracellular matrix in the region of the horizontal myoseptum that influences the growth of motor axons

Tenascin C (TNC) Protein Profile

Protein Summary

This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration.

Gene names and symbols associated with Tenascin C Proteins (TNC)

  • tenascin C (tnc)
  • tenascin C (TNC)
  • tenascin C (MCYG_00667)
  • tenascin C (Tnc)
  • 150-225 protein
  • AI528729 protein
  • C130033P17Rik protein
  • cytotactin protein
  • GMEM protein
  • GP protein
  • Hxb protein
  • JI protein
  • P230 protein
  • Ten protein
  • tenascin-C protein
  • tenc protein
  • TN protein
  • TN-C protein
  • wu:fk04d02 protein

Protein level used designations for Tenascin C Proteins (TNC)

tenascin C , tenascin C (hexabrachion) , tenascin-like , GP 150-225 , cytotactin , glioma-associated-extracellular matrix antigen , hexabrachion (tenascin) , myotendinous antigen , neuronectin , tenascin , tenascin-C isoform 14/AD1/16 , hexabrachion , etID309720.5

398332 Xenopus laevis
702720 Macaca mulatta
742736 Pan troglodytes
9225869 Arthroderma otae CBS 113480
100049835 Equus caballus
100414580 Callithrix jacchus
100451868 Pongo abelii
100473350 Ailuropoda melanoleuca
100557589 Anolis carolinensis
100598677 Nomascus leucogenys
3371 Homo sapiens
21923 Mus musculus
116640 Rattus norvegicus
100725345 Cavia porcellus
396440 Gallus gallus
481689 Canis lupus familiaris
397460 Sus scrofa
540664 Bos taurus
100301551 Oryctolagus cuniculus
101118337 Ovis aries
30037 Danio rerio
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