TNC Protein (AA 23-621) (His tag)

Catalog No. ABIN7275754

Product Details

Target: TNC (Tenascin C (TNC))

Protein Type: Recombinant

Protein Characteristics: AA 23-621

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This TNC protein is labelled with His tag.

Purpose: Mouse Tenascin Protein

Sequence: Gly23-Ser621

Characteristics: Recombinant Mouse Tenascin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly23-Ser621.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: TNC (Tenascin C (TNC))

Alternative Name: Tenascin (TNC Products)

Synonyms: tn Protein, 150-225 Protein, GMEM Protein, GP Protein, HXB Protein, JI Protein, TN Protein, TN-C Protein, AI528729 Protein, C130033P17Rik Protein, Hxb Protein, Ten Protein, cytotactin Protein, tenascin-C Protein, P230 Protein, tenc Protein, wu:fk04d02 Protein, tenascin C L homeolog Protein, tenascin C Protein, tnc.L Protein, TNC Protein, MCYG_00667 Protein, tnc Protein, Tnc Protein

Background: Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens, it also influences cell phenotype directly through interactions with cell surface receptors.

Molecular Weight: 65.65 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development