Tetraspanin 8 Proteins (TSPAN8)

The protein encoded by TSPAN8 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Additionally we are shipping Tetraspanin 8 Antibodies (99) and Tetraspanin 8 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TSPAN8 7103 P19075
TSPAN8 216350 Q8R3G9
Rat TSPAN8 TSPAN8 171048  
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Top Tetraspanin 8 Proteins at antibodies-online.com

Showing 4 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,041.49
Details
Human Cells Human His tag 10 μg Log in to see 20 to 21 Days
$250.80
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details

TSPAN8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine)

More Proteins for Tetraspanin 8 (TSPAN8) Interaction Partners

Xenopus laevis Tetraspanin 8 (TSPAN8) interaction partners

  1. overexpression of tm4sf3 promoted development of annular pancreas.

Human Tetraspanin 8 (TSPAN8) interaction partners

  1. LCMR1 (show MED19 Proteins) modulation was sufficient to positively regulate endogenous Tspan8 expression, with concomitant in vitro phenotypic changes such as loss of melanoma cell-matrix adherence and increase in invasion, and Tspan8 expression promoted tumourigenicity in vivo.

  2. Data indicate a regulatory role for tetraspanin 8 (Tspan8) in melanoma progression by modulating cell-matrix interactions through beta1 integrin - integrin-linked kinase (ILK (show ILK Proteins)) axis and establish Tspan8 as a negative regulator of ILK (show ILK Proteins) activity.

  3. TSPAN8 might be important for the orchestration of meprin beta (show MEP1B Proteins) at the cell surface with impact on certain proteolytic processes

  4. Knocking down TSPAN8 in AEG-1 (show MTDH Proteins)-overexpressing human hepatocellular carcinoma (HCC (show FAM126A Proteins)) cells markedly inhibited invasion and migration without affecting proliferation. TSPAN8 knockdown profoundly abrogated AEG-1 (show MTDH Proteins)-induced primary tumor and intrahepatic metastasis in an orthopic xenograft model in athymic nude mice

  5. Knockdown and knockout models revealed that CD151 (show CD151 Proteins) and Tspan8 act as molecular facilitators in wound healing, angiogenesis and tumor progression. [review]

  6. Results provide evidence that TSPAN8 may contribute to the pathogenesis of lung cancer by promoting cell viability and proliferation.

  7. TSPAN8 is involved in tumor progression and is an independent prognostic classifier in patients with gastric cancer.

  8. This novel nuclear localization of TM4SF3 depends on androgen-induced nuclear localization of androgen receptor (AR (show AR Proteins)) in both androgen-dependent and androgen-independent prostate cancer cell lines

  9. Our data suggest that TSPAN8-LEL may play an important role in mCRC cell invasion, and that the antibody we have developed could be a useful tool for inhibiting the invasion of TSPAN8-expressing mCRCs.

  10. Based on nasopharyngeal TSPAN8 gene expression in readily available Nasopharyngeal aspirate samples , we can discriminate between severity of disease in Respiratory syncytial virus infected infants.

Mouse (Murine) Tetraspanin 8 (TSPAN8) interaction partners

  1. Transplantation studies provided definitive evidence that a TSPAN8-high subpopulation is enriched for spermatogonial stem cells.

  2. results argue for a role for Tspan8 in body-weight regulation in males, but do not show differences in T2D-associated traits that were anticipated from previous human genome-wide association studies.

  3. Results suggest that alterations in gene expression of Gata6, Tspan8, S100a8, and Lmo2 may act via novel pathways that play functionally important roles in Men1-associated tumor progression.

Tetraspanin 8 (TSPAN8) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.

Gene names and symbols associated with Tetraspanin 8 Proteins (TSPAN8)

  • tetraspanin 8 L homeolog (tspan8.L)
  • tetraspanin-1 (LOC409511)
  • tetraspanin 8 (TSPAN8)
  • tetraspanin 8 (tspan8)
  • tetraspanin 8 (Tspan8)
  • C76990 protein
  • CO-029 protein
  • CO-29 protein
  • E330007O21Rik protein
  • GB13255 protein
  • MGC64550 protein
  • tetraspanin-8 protein
  • Tm4sf3 protein
  • TSPAN-8 protein
  • TSPAN8 protein

Protein level used designations for Tetraspanin 8 Proteins (TSPAN8)

tetraspanin 8 , transmembrane 4 superfamily member 3 , tetraspanin-8 , tspan-8 , tumor-associated antigen CO-029 , D6.1A

GENE ID SPECIES
380553 Xenopus laevis
409511 Apis mellifera
417854 Gallus gallus
496915 Xenopus (Silurana) tropicalis
718622 Macaca mulatta
743174 Pan troglodytes
474448 Canis lupus familiaris
7103 Homo sapiens
216350 Mus musculus
171048 Rattus norvegicus
617508 Bos taurus
100174494 Pongo abelii
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