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Tumor Protein P73 Proteins (TP73)

TP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. Additionally we are shipping Tumor Protein p73 Antibodies (205) and Tumor Protein p73 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TP73 22062 Q9JJP2
TP73 7161 O15350
Rat TP73 TP73 362675  
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Top Tumor Protein p73 Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 25 μg Log in to see 9 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

TP73 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,

More Proteins for Tumor Protein P73 (TP73) Interaction Partners

Mouse (Murine) Tumor Protein P73 (TP73) interaction partners

  1. Results indicate that p73 (show ARHGAP24 Proteins) regulates basal and starvation-induced fuel metabolism in the liver, a finding that is likely to be highly relevant for metabolism-associated disorders, such as diabetes and cancer.

  2. MDM2 (show MDM2 Proteins) mediates p73 (show ARHGAP24 Proteins) ubiquitination

  3. p73 (show ARHGAP24 Proteins) is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF (show VEGFA Proteins) and TGFbeta (show TGFB1 Proteins) signaling

  4. Although mouse TIGAR (show C12orf5 Proteins) expression is clearly induced in the intestines of mice following DNA-damaging stress of ionizing radiation, that was not dependent on p53 (show TP53 Proteins) or TAp73.

  5. Ribosomal proteins L11 (show RPL11 Proteins) and L5 activate TAp73 by overcoming MDM2 (show MDM2 Proteins) inhibition.

  6. the p73 (show ARHGAP24 Proteins) status has to be considered when studying the regulatory role of p53 (show TP53 Proteins) protein in gliomagenesis [review]

  7. Suggest that TAp73 promotes anabolism to counteract cellular senescence rather than to support proliferation.

  8. p63 (show CKAP4 Proteins) antagonizes p53 (show TP53 Proteins) to promote cellular survival, whereas p73 (show ARHGAP24 Proteins) regulates self-renewal and p53 (show TP53 Proteins)-mediated apoptosis versus senescence.

  9. Inhibition of TAp73 results in an accumulation of HIF-1alpha (show HIF1A Proteins) and up-regulation of HIF-1alpha (show HIF1A Proteins) target genes.

  10. The transcription factor TAp73 opposes HIF-1 (show HIF1A Proteins) activity through a nontranscriptional mechanism, thus affecting tumor angiogenesis.

Human Tumor Protein P73 (TP73) interaction partners

  1. Similar to TAp73, DNp73 is stabilized by hypoxia in a HIF-1a-dependent manner, which otherwise is degraded by Siah1.

  2. Data indicate tumor suppressors TP73, RASSF1A (show RASSF1 Proteins), MLH1 (show MLH1 Proteins) and BRCA1 as possible biomarkers to distinguish Pleomorphic invasive lobular cancer (pleomorphic ILC (show CCL27 Proteins)} from classic ILC (show CCL27 Proteins) and infiltrative ductal cancer (IDC (show LMNA Proteins)).

  3. This review establishes the possibility that p73 is indeed capable of both promoting and inhibiting angiogenesis, depending on the cellular context. [review]

  4. Mechanistic investigations indicated that DNp73 acted by attenuating expression of miR (show MLXIP Proteins)-885-5p, a direct regulator of the IGF1 (show IGF1 Proteins) receptor (IGF1R (show IGF1R Proteins)) responsible for stemness marker expression.

  5. Tyrosine-99 phosphorylation determines the regulation of tumor suppressor p73.

  6. MDM2 (show MDM2 Proteins) mediates p73 ubiquitination

  7. Mdm2 (show MDM2 Proteins) overexpression and p73 loss cooperate in genomic instability and tumor development, indicating that the oncogenic function of Mdm2 (show MDM2 Proteins) is a combined effect of inhibiting p53 (show TP53 Proteins) and p73 functions

  8. Authors demonstrate that IGFBP3 (show IGFBP3 Proteins) is a direct TAp73alpha (the p73 isoform that contains the trans-activation domain) target gene and activates the expression of IGFBP3 (show IGFBP3 Proteins) in actively proliferating cells.

  9. TAp73 suppresses BNIP3 (show BNIP3 Proteins) expression, directly binding its gene promoter.

  10. Positive association between RPRM and p73 expression suggest that other members of the p53 gene family may participate in the regulation of RPRM expression.

Zebrafish Tumor Protein P73 (TP73) interaction partners

Tumor Protein p73 (TP73) Protein Profile

Protein Summary

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.

Gene names and symbols associated with Tumor Protein P73 Proteins (TP73)

  • tumor protein p73 (TP73)
  • uncharacterized LOC515105 (LOC515105)
  • tumor protein p73 (tp73)
  • transformation related protein 73 (Trp73)
  • tumor protein p73 (Tp73)
  • p73 protein
  • TAp73 protein
  • Tp73 protein
  • Trp73 protein
  • zp73theta protein

Protein level used designations for Tumor Protein P73 Proteins (TP73)

tumor protein p73 , tumor protein p73-like , p53-like transcription factor , p53-related protein , transformation related protein 73

489620 Canis lupus familiaris
515105 Bos taurus
419382 Gallus gallus
100052597 Equus caballus
100170633 Oryzias latipes
100554137 Anolis carolinensis
22062 Mus musculus
7161 Homo sapiens
362675 Rattus norvegicus
368221 Danio rerio
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