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Tumor Protein p73 Products

(Tumor Protein P73 (TP73))
This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011].

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Featured Tumor Protein p73 Categories

Tumor Protein p73 Antibodies

High quality antibodies with extensive validation data.

Tumor Protein p73 ELISA Kits

Reliable ELISA kits for a wide range of species.

Tumor Protein p73 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Tumor Protein p73 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (11)
Cat. No. ABIN6256817
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (6)
Cat. No. ABIN3181893
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (6)
Cat. No. ABIN3187855
Quantity 100 μL
Datasheet Datasheet

Recommended Tumor Protein p73 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380678
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648649
Quantity 96 tests
Datasheet Datasheet

Recommended Tumor Protein p73 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323404
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3085444
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3130163
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Tumor Protein p73 products

Cam, Charan, Welker, Dravid, Studebaker, Leonard, Pierson, Nakano, Beattie, Hwang, Kambhampati, Nazarian, Finlay, Cam: "ΔNp73/ETS2 complex drives glioblastoma pathogenesis- targeting downstream mediators by rebastinib prolongs survival in preclinical models of glioblastoma." in: Neuro-oncology, (2019) (PubMed).

Liu, Yang, Jing, Ren, Wei, Zhang, Zhang, Duan, Zhou, Sun: "Silica nanoparticle exposure inducing granulosa cell apoptosis and follicular atresia in female Balb/c mice." in: Environmental science and pollution research international, Vol. 25, Issue 4, pp. 3423-3434, (2018) (PubMed).

Makino, Gutmann, Kosnopfel, Niessner, Forschner, Garbe, Sinnberg, Schittek: "Melanoma cells resistant towards MAPK inhibitors exhibit reduced TAp73 expression mediating enhanced sensitivity to platinum-based drugs." in: Cell death & disease, Vol. 9, Issue 9, pp. 930, (2018) (PubMed).

Kumar, Talluri, Pal, Yuan, Lu, Nanjappa, Samur, Munshi, Shammas: "Role of apurinic/apyrimidinic nucleases in the regulation of homologous recombination in myeloma: mechanisms and translational significance." in: Blood cancer journal, Vol. 8, Issue 10, pp. 92, (2018) (PubMed).

Yang, Yang, Tang, Zhang, Zhu, Wang, Wang, Ma: "Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response." in: Molecular medicine reports, Vol. 17, Issue 6, pp. 7545-7552, (2018) (PubMed).

Papaspyropoulos, Bradley, Thapa, Leung, Toskas, Koennig, Pefani, Raso, Grou, Hamilton, Vlahov, Grawenda, Haider, Chauhan, Buti, Kanapin, Lu, Buffa, Dianov, von Kriegsheim, Matallanas, Samsonova et al.: "RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73. ..." in: Nature communications, Vol. 9, Issue 1, pp. 424, (2018) (PubMed).

González, De la Rosa, Rufini, Rodríguez-Hernández, Navarro-Villarán, Marchal, Pereira, De la Mata, Müller-Schilling, Pascasio-Acevedo, Ferrer-Ríos, Gómez-Bravo, Padillo, Muntané: "Role of p63 and p73 isoforms on the cell death in patients with hepatocellular carcinoma submitted to orthotopic liver transplantation." in: PLoS ONE, Vol. 12, Issue 3, pp. e0174326, (2017) (PubMed).

Lee, Pelletier: "Dependence of p53-deficient cells on the DHX9 DExH-box helicase." in: Oncotarget, Vol. 8, Issue 19, pp. 30908-30921, (2017) (PubMed).

Ng, Chan, Chai, Tong, Guan, Lee, Yuan, Xie, Lee, Dusetti, Carrier, Ma: "TP53INP1 Downregulation Activates a p73-Dependent DUSP10/ERK Signaling Pathway to Promote Metastasis of Hepatocellular Carcinoma." in: Cancer research, Vol. 77, Issue 17, pp. 4602-4612, (2017) (PubMed).

Prabhu, Hong, Allen, Zhang, Lulla, Dicker, El-Deiry: "Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation." in: Cancer research, Vol. 76, Issue 7, pp. 1989-99, (2016) (PubMed).

Synonyms and alternative names related to Tumor Protein p73

tumor protein p73 (TP73), tumor protein p73 (Tp73), tumor protein p73 (tp73), transformation related protein 73 (Trp73), P73, p73, TAp73, TP73, tp73, Tp73, Trp73, zp73theta

Protein level used designations for Tumor Protein p73

  • transformation related protein 73
  • tumor protein p73
  • tumor protein p73-like
  • p53-like transcription factor
  • p53-related protein
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