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anti-Human Angiotensin II Type 2 Receptor Antibodies:
anti-Mouse (Murine) Angiotensin II Type 2 Receptor Antibodies:
anti-Rat (Rattus) Angiotensin II Type 2 Receptor Antibodies:
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Human Polyclonal Angiotensin II Type 2 Receptor Primary Antibody for ELISA, ICC - ABIN4278731
Hafko, Villapol, Nostramo, Symes, Sabban, Inagami, Saavedra: Commercially available angiotensin II At₂ receptor antibodies are nonspecific. in PLoS ONE 2013
Show all 9 Pubmed References
angiotensin II type 2 receptor activation in inguinal adipocytes opposes norepinephrine-induced uncoupling protein-1 (UCP1 (show UCP1 Antibodies)) production and aspects of cellular respiration
loss of AT2 R is associated with podocyte loss/dysfunction and is mediated, at least in part, via augmented ectopic hedgehog interacting protein (show HHIP Antibodies) expression in podocytes
In this genomewide association study, we found that variants at the EBF1 (show EBF1 Antibodies), EEFSEC (show EEFSEC Antibodies), AGTR2, WNT4 (show WNT4 Antibodies), ADCY5 (show ADCY5 Antibodies), and RAP2C (show RAP2C Antibodies) loci were associated with gestational duration and variants at the EBF1 (show EBF1 Antibodies), EEFSEC (show EEFSEC Antibodies), and AGTR2 loci with preterm birth.
crystal structures of human AT2R bound to an AT2R-selective ligand and to an AT1R (show AGTR1 Antibodies)/AT2R dual ligand, capturing the receptor in an active-like conformation
Suggest a gender-specific association between the AT2R -1332 A/G polymorphism and the occurrence of carotid plaque and the history of cerebrovascular insult in advanced carotid atherosclerosis.
peripheral and central arterial pressures and pulse wave augmentation indexes (AIx(P), AIx(C1), AIx(C2)), pulse wave velocity (PWV), daily urinary sodium excretion were measured and did genetic studies of AGTR1 (show AGTR1 Antibodies) A1166C and AGTR2 G1675A polymorphisms.
Significant overrepresentation of AT2R-1332 AA genotype in female multiple sclerosis patients was found, compared to female controls.
These data suggest that AT2R inhibits ligand-induced AT1R signaling through the PKC-dependent pathway.
Ang II (show AGT Antibodies)-induced upregulation of ATF3 (show ATF3 Antibodies) and SUMO1 (show SUMO1 Antibodies) in vitro and in vivo was blocked by Ang II (show AGT Antibodies) type I receptor antagonist olmesartan. Moreover, Ang II (show AGT Antibodies) induced ATF3 (show ATF3 Antibodies) SUMOylation at lysine 42, which is SUMO1 (show SUMO1 Antibodies) dependent
The A1166C polymorphism of AT1R (show AGTR1 Antibodies), A1675G and C3123A polymorphisms of AT2R were analyzed. The A1675G polymorphism of AT2R might be associated with preeclampsia
crosstalk between AT2 receptor stimulation and PPARgamma (show PPARG Antibodies) activation could contribute to attenuation of vascular intimal proliferation
Deletion of AT2 receptor reduced SHP-1 activity and restored VEGF actions, leading to an increased blood flow reperfusion after ischemia in diabetes mellitus.
Our current results reinforce the notion that the AT2R has a physiological role in the conservation of insulin (show INS Antibodies) action
Ultra-high doses did not influence the ACE2 (show ACE2 Antibodies)/AT2R/Mas (show MAS1 Antibodies) axis and promoted renal injury with increased renal ERK1/2 (show MAPK1/3 Antibodies) activation and exaggerated fibronectin (show FN1 Antibodies) expression in db/db (show LEPR Antibodies) mice. Our study demonstrates dose-related effects of candesartan in diabetic nephropathy: intermediate-high dose candesartan is renoprotective, whereas ultra-high dose candesartan induces renal damage.
This study aimed to define whether sex chromosome complement (SCC (show CYP11A1 Antibodies)) may differentially modulate sex differences in relative gene expression of basal Agtr1a (show AGTR1 Antibodies), Agtr2, and Mas1 (show MAS1 Antibodies) receptors at fore/hindbrain nuclei and at medulla/cortical kidney.
AT2R-dependent interleukin-17 (show IL17A Antibodies) production by T lymphocyte is necessary for collateral artery growth.
Altered expression of AT1 and AT2 receptors with aging may induce mitochondrial dysfunction, the main risk factor for neurodegeneration.
AT2R inhibits adipogenic differentiation in mesenchymal stem cells. Moreover, this inhibitory effect is associated with Wnt10b (show WNT10B Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.
These results suggest that nerve growth factor-mediated neurite outgrowth is suppressed by AT2 receptor signaling via the nitric oxide-cyclic GMP (show NT5C2 Antibodies)-PKG (show PRKG1 Antibodies) pathway.
Luminal ANG II is internalized as a complex with AT1R/AT2R heterodimers to target endoplasmic reticulum in LLC-PK1 cells, where it might trigger intracellular calcium responses.
AT1 (show AGTR1 Antibodies) and AT2 receptors heterodimerize and are involved in the angiotensin II effect on SERCA (show ATP2A3 Antibodies) in proximal kidney tubules.
AT2 receptors are positively coupled to the proliferative response of vascular smooth muscle cells to angiotensin II.
Glomerular eNOS (show NOS3 Antibodies) gene expression was studied during postnatal maturation and AT1 receptor (show AGTRAP Antibodies) inhibition.
Data suggest that AGTR2 (and angiotensin-converting enzyme (show ACE Antibodies)) mRNA levels are transiently up-regulated in ovarian theca cells during preovulatory period.
data suggest that G alpha(i3), Shc (show SHC1 Antibodies), Grb2 (show GRB2 Antibodies), Ras, and Raf-1 (show RAF1 Antibodies) link Src (show SRC Antibodies) to activation of MAPK (show MAPK1 Antibodies) and to the AT(2)-dependent increase in eNOS (show NOS3 Antibodies) expression in PAECs
Abundance of AGTR2 mRNA in granulosa cells was higher in healthy compared with atretic follicles, whereas in theca cells, it did not change
The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.
angiotensin II type-2 receptor
, type-2 angiotensin II receptor
, AT2 receptor
, angiotensin II type 2 receptor
, angiotensin receptor 2
, angiotensin II receptor type 2
, angiotensin type II receptor
, Type-2 angiotensin II receptor
, angiotensin II subtype 2 receptor, AT2