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Browse our anti-Immunoglobulin kappa Variable 1-27 (IGKV1-27) Antibodies

Full name:
anti-Immunoglobulin kappa Variable 1-27 Antibodies (IGKV1-27)
On www.antibodies-online.com are 7 Immunoglobulin kappa Variable 1-27 (IGKV1-27) Antibodies from 6 different suppliers available. A total of 9 Immunoglobulin kappa Variable 1-27 products are currently listed.
Synonyms:
A20, OTUD7C, TNFA1P2
list all antibodies Gene Name GeneID UniProt
IGKV1-27 7128 P21580
IGKV1-27    
IGKV1-27    

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Top referenced anti-Immunoglobulin kappa Variable 1-27 Antibodies

  1. Human Monoclonal IGKV1-27 Primary Antibody for WB - ABIN2668824 : Wu, Xu, Chang: The promyelocytic leukemia protein represses A20-mediated transcription. in The Journal of biological chemistry 2002 (PubMed)

More Antibodies against Immunoglobulin kappa Variable 1-27 Interaction Partners

Human Immunoglobulin kappa Variable 1-27 (IGKV1-27) interaction partners

  1. Our study confirms the involvement of the TNFAIP3 (show TNFAIP3 Antibodies) tumor suppressor gene in classic Hodgkin lymphoma.

  2. A20 (show TNFAIP3 Antibodies) may be a potential therapeutic target for DLBCL.

  3. There is a significantly higher occurrence of the A20 (show TNFAIP3 Antibodies) rs143002189 polymorphism in diffuse large B cell lymphoma (DLBCL) compared to non-neoplastic controls and other types of B cell malignancies.

  4. HMBA was able to increase prostratin-induced phosphorylation and degradation of NF-kappaB (show NFKB1 Antibodies) inhibitor IkappaBalpha (show NFKBIA Antibodies), thereby enhancing and prolonging prostratin-induced nuclear translocation of NF-kappaB (show NFKB1 Antibodies), a prerequisite for stimulation of transcription initiation

  5. A Japanese family case with juvenile onset Behcet's disease caused by TNFAIP3 (show TNFAIP3 Antibodies) mutation.

  6. TNFAIP3 gene polymorphisms (rs9494885 and rs7753873) are associated with the susceptibility to allergic rhinitis in the Chinese Han population.

  7. A20 (show TNFAIP3 Antibodies) significantly inhibited poly(I:C)-induced cytokine production, and this effect was related to the inhibition of NF-kappaB (show NFKB1 Antibodies) signaling. These results suggest that the downregulation of A20 (show TNFAIP3 Antibodies) increased the susceptibility of keratinocytes to external stimuli, thus contributing to the development of psoriasis.

  8. we indentified 13 susceptibility SNPs and a long risk haplotype for SLE at TNFAIP3 gene locus. Our results suggest that TNFAIP3 is a susceptible gene for SLE in Han Chinese population.

  9. By using bioinformatics analysis tool (Targetscan), the 3' untranslated region (3'UTR (show UTS2R Antibodies)) of A20 (show TNFAIP3 Antibodies) gene was found to be a target of miR (show MLXIP Antibodies)-125a. The expression level of miR (show MLXIP Antibodies)-125a in pancreatic cancer tissues from chemo-sensitive patients was significantly lower than that from chemo-resistant patients, and was inversely correlated with the A20 (show TNFAIP3 Antibodies) mRNA.

  10. Data suggest an association of TNFAIP3 (show TNFAIP3 Antibodies) SNPs with susceptibility to chronic ITP (show ITPA Antibodies). Together with previous reports, finding provides further evidence for TNFAIP3 (show TNFAIP3 Antibodies) being a general autoimmunity gene.

Immunoglobulin kappa Variable 1-27 (IGKV1-27) Antigen Profile

Antigen Summary

This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with Immunoglobulin kappa Variable 1-27 (IGKV1-27)

  • tumor necrosis factor, alpha-induced protein 3 (TNFAIP3) antibody
  • A20 antibody
  • OTUD7C antibody
  • TNFA1P2 antibody

Protein level used designations for IGKV1-27

OTU domain-containing protein 7C , TNF alpha-induced protein 3 , putative DNA-binding protein A20 , tumor necrosis factor alpha-induced protein 3 , tumor necrosis factor inducible protein A20 , zinc finger protein A20

GENE ID SPECIES
7128 Homo sapiens
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