CD48 antibody (APC)

Catalog No. ABIN1106423

The Mouse Monoclonal anti-CD48 antibody has been validated for FACS. It is suitable to detect CD48 in samples from Human and Monkey.

Quick Overview for CD48 antibody (APC) (ABIN1106423)

Target: CD48

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD48 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: MEM-102

Product Details anti-CD48 Antibody (APC)

Specificity: This antibody recognises the CD48 antigen which is widely distributed on leucocytes with a distinctive reaction pattern. The antigen is structurally closely related to the B-cell activation antigen Blast-1.

Purification: Purified IgG prepared by ion exchange chromatography.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute with 1 mL distilled water.

Concentration: 0.1 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Prior to and following reconstitution store the antibody at 2-8 °C.

Target Details for CD48

Target: CD48

Alternative Name: CD48

Background: CD48 is a glycosyl phophatidyl inositol (GPI) anchored cell surface protein also known as Blast1, HuLy m3, BCM1 (in mouse), and OX45 (in rat). CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibrolasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2. The CD48 antigen is closely related to the activation antigen, Blast 1.Synonyms: B-lymphocyte activation marker BLAST-1, BCM1, BCM1 surface antigen, BLAST1, Leukocyte antigen MEM-102, MEM-102, TCT.1

Gene ID: 962

NCBI Accession: NP_001769

UniProt: P09326