CHEK1 antibody
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- Target See all CHEK1 Antibodies
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CHEK1 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, Mouse.
- Purification
- Purified
- Clone
- 2G1D5
- Isotype
- IgG1
- Top Product
- Discover our top product CHEK1 Primary Antibody
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anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibody
CHEK1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (pSer296) antibodyCHEK1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (pSer286) antibodyCHEK1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (pSer301) antibodyCHEK1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (pSer345) antibodyCHEK1 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (Middle Region) antibodyCHEK1 Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibodyCHEK1 Reactivity: Human WB, IHC (p), DB Host: Rabbit Polyclonal RB7845-RB18425 unconjugated
anti-Checkpoint Kinase 1 (CHEK1) antibodyCHEK1 Reactivity: Human, Mouse WB, ELISA Host: Mouse Monoclonal 2G1D5 unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibodyCHEK1 Reactivity: Mouse, Chicken ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) antibodyCHEK1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Monoclonal 2F2 unconjugated Recombinant Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS, 0.03 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
- Alternative Name
- CHK1 (CHEK1 Products)
- Background
- CHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Chk1 can also phosphorylate p53 at Ser20 in vitro.Synonyms: CHEK-1, CHEK1, CHK1 checkpoint homolog, Serine/threonine-protein kinase Chk1
- Molecular Weight
- 56 kDa
- Gene ID
- 1111
- Pathways
- p53 Signaling, Apoptosis, Cell Division Cycle, DNA Damage Repair
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