Afadin antibody (AA 1814-1829)
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- Target See all Afadin (MLLT4) Antibodies
- Afadin (MLLT4)
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Binding Specificity
- AA 1814-1829
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Reactivity
- Human, Rat, Mouse, Dog
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Afadin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects L-Afadin.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse, rat, dog
- Purification
- Protein G
- Immunogen
- Peptide 1814-1829 aa of rat l-afadin
- Clone
- 3
- Isotype
- IgG1
- Top Product
- Discover our top product MLLT4 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2 - 8 °C.
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- Target
- Afadin (MLLT4)
- Alternative Name
- MLLT4 / AF6 / Afadin (MLLT4 Products)
- Synonyms
- MLLT4 antibody, af-6 antibody, af6 antibody, si:ch211-278j12.1 antibody, AF6 antibody, RP3-431P23.3 antibody, 5033403D15Rik antibody, Af-6 antibody, Afadin antibody, Gm314 antibody, I-afadin antibody, S-afadin antibody, Af6 antibody, afadin, adherens junction formation factor antibody, afadin, adherens junction formation factor L homeolog antibody, afadin, adherens junction formation factor a antibody, afadin antibody, AFDN antibody, afdn.L antibody, afdna antibody, LOC589923 antibody, LOC100177180 antibody, afdn antibody, Afdn antibody
- Background
- Afadin is an actin filament-binding protein that is involved in cell-cell adherens junctions (AJs) which directly interacts with the alpha herpus virus receptor, a member of the immunoglobulin supergene family. Afadin is colocalized with nectin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. L-Afadin has been isolated as an F-actin-binding protein from rat brain. L-afadin is ubiquitously expressed and specifically localized at zonula adherens (ZA) in epithelial cells and at cell-cell adherens junctions (AJs) in non-epithelial cells. L-afadin has a splice variant, named small intestine absorptive afadin (s-afadin) which is abundantly expressed in neural tissue.Synonyms: Myeloid/lymphoid Or Mixed-lineage Leukemia Translocated To 4, Protein AF-6
- Gene ID
- 26955
- NCBI Accession
- NP_037349
- UniProt
- O35889
- Pathways
- Cell-Cell Junction Organization
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