Afadin antibody (N-Term)

Catalog No. ABIN925787

Product Details anti-Afadin Antibody

Target: Afadin (MLLT4)

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Chicken, Drosophila melanogaster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Afadin antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat (Rattus), Mouse (Murine), Chicken, Fruit Fly (Drosophila melanogaster)

Immunogen: MLLT4 antibody was raised in rabbit using the N terminal of MLLT4 as the immunogen

Application Details

Application Notes: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

MLLT4 Blocking Peptide, catalog no. 33R-3641, is also available for use as a blocking control in assays to test for specificity of this MLLT4 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Afadin

Target: Afadin (MLLT4)

Alternative Name: MLLT4 (MLLT4 Products)

Synonyms: MLLT4 antibody, af-6 antibody, af6 antibody, si:ch211-278j12.1 antibody, AF6 antibody, RP3-431P23.3 antibody, 5033403D15Rik antibody, Af-6 antibody, Afadin antibody, Gm314 antibody, I-afadin antibody, S-afadin antibody, Af6 antibody, afadin, adherens junction formation factor antibody, afadin, adherens junction formation factor L homeolog antibody, afadin, adherens junction formation factor a antibody, afadin antibody, AFDN antibody, afdn.L antibody, afdna antibody, LOC589923 antibody, LOC100177180 antibody, afdn antibody, Afdn antibody

Background: AF6 is a Ras target that regulates cell-cell adhesions downstream of Ras activation. It is fused with MLL in leukemias caused by t(6,11) translocations. Synonyms: Polyclonal MLLT4 antibody, Anti-MLLT4 antibody, myeloid/lymphoid or mixed-lineage leukemia, translocated to, 4 antibody, RP3-470B24.4 antibody, AF-6 antibody, AF6 antibody, AFADIN antibody, FLJ34371 antibody, RP3-431P23.3 antibody.

Pathways: Cell-Cell Junction Organization