NR1I3 antibody (C-Term)

Catalog No. ABIN1108490

The Rabbit Polyclonal anti-NR1I3 antibody has been validated for WB. It is suitable to detect NR1I3 in samples from Human, Mouse, Rat, Dog and Pig.

Quick Overview for NR1I3 antibody (C-Term) (ABIN1108490)

Target: NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Reactivity: Human, Mouse, Rat, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR1I3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NR1I3 Antibody

Binding Specificity: C-Term

Sequence: FHGTLRKLQL QEPEYVLLAA MALFSPDRPG VTQRDEIDQL QEEMALTLQS

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Pig, DogSpecies reactivity (tested):Human

Purification: Purified using Protein A affinity column

Immunogen: The immunogen for anti-NR1I3 antibody: synthetic peptide directed towards the C terminal of human NR1I3.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for NR1I3

Target: NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Alternative Name: NR1I3 / CAR

Background: NR1I3 is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members.Synonyms: Constitutive activator of retinoid response, Constitutive androstane receptor, MB67, Nuclear receptor subfamily 1, Orphan nuclear receptor MB67, group I, member 3

Gene ID: 9970

NCBI Accession: NP_005113

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway