CD3 antibody (Biotin)
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- Target See all CD3 Antibodies
- CD3
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD3 antibody is conjugated to Biotin
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Application
- Flow Cytometry (FACS)
- Specificity
- Human CD3, Mr 20 kDa
- Characteristics
- Mouse Anti-Human CD3-BIOT
- Immunogen
- Human peripheral blood lymphocytes from a patient with Sézary's syndrome and infant thymocytes
- Clone
- UCHT1
- Isotype
- IgG1
- Top Product
- Discover our top product CD3 Primary Antibody
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- Application Notes
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Activ - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, SPRD, CY5, PE/CY5.5, PE/CY7, 10 L/106 cells APC/CY7, PACBLU, AF488, AF647, and AF700 conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Comment
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in vitro activation of T Cells
- Restrictions
- For Research Use only
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- Buffer
- 100 tests in 1.0 mL of PBS/Sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
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Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - Storage
- 4 °C
- Storage Comment
- Store at 2-8°C
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- Target
- CD3
- Alternative Name
- CD3 (CD3 Products)
- Background
- CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). CD3 is expressed on 70-80 % of normal peripheral blood lymphocytes and on 10-20 % of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation.
- Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
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