TMEM176B antibody (AA 25-150)

Catalog No. ABIN1385213

The Rabbit Polyclonal anti-TMEM176B antibody has been validated for ELISA, ICC, IF (cc), IF (p), IHC (fro) and IHC (p). It is suitable to detect TMEM176B in samples from Human.

Quick Overview for TMEM176B antibody (AA 25-150) (ABIN1385213)

Target: TMEM176B (Transmembrane Protein 176B (TMEM176B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM176B antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TMEM176B Antibody

Binding Specificity: AA 25-150

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LR8/TMEM176B

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TMEM176B

Target: TMEM176B (Transmembrane Protein 176B (TMEM176B))

Alternative Name: LR8/TMEM176B

Background:

Synonyms: LR 8, TMEM176B, Transmembrane protein 176B, T176B_HUMAN.

Background: Chromosome 7 is about 158 milllion bases long, encodes over 1000 genes and makes up about 5 % of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The LR8 gene product has been provisionally designated LR8 pending further characterization.