Calsyntenin 2 antibody (PE)

Catalog No. ABIN1425995

Product Details anti-Calsyntenin 2 Antibody (PE)

Target: Calsyntenin 2 (CLSTN2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calsyntenin 2 antibody is conjugated to PE

Application: Please inquire

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLSTN2

Isotype: IgG

Application Details

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for Calsyntenin 2

Target: Calsyntenin 2 (CLSTN2)

Alternative Name: Clstn2 (CLSTN2 Products)

Background:

Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.

Subcellular location: Extracellular

Synonyms: Alc, Alcadein, Alcadein Gamma, Alcagamma, Alzheimer's disease related cadherin like protein, Calsyntenin 2, CLSTN 2, CS 2, CS2, FLJ39113, FLJ39499, MGC119560, CSTN2_HUMAN.