Claudin 4 antibody (C-Term)
Quick Overview for Claudin 4 antibody (C-Term) (ABIN1449984)
Target
See all Claudin 4 (CLDN4) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- CLAUDIN4 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human CLAUDIN4.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- Claudin 4 (CLDN4)
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Alternative Name
- Claudin-4 / CLDN4
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Background
- CLAUDIN4 is an integral membrane protein belonging to the claudin family, a family of cellular adhesion molecules that are components of tight junctions. CLAUDIN4 is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. The CLAUDIN4 gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. CLAUDIN4 is frequently overexpressed in ovarian and other epithelial cancers.Synonyms: CPE-R, CPE-Receptor, CPER, CPETR1, Clostridium perfringens enterotoxin receptor, WBSCR8, Williams-Beuren syndrome chromosomal region 8 protein
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Molecular Weight
- 23 kDa
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Gene ID
- 1364
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NCBI Accession
- NP_001296
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Pathways
- Hepatitis C
Target
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