IRF2BP2 antibody (C-Term)

Catalog No. ABIN1450118

The Rabbit Polyclonal anti-IRF2BP2 antibody has been validated for WB, IF and EIA. It is suitable to detect IRF2BP2 in samples from Human and Mouse.

Quick Overview for IRF2BP2 antibody (C-Term) (ABIN1450118)

Target: IRF2BP2 (Interferon Regulatory Factor 2 Binding Protein 2 (IRF2BP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF2BP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-IRF2BP2 Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid synthetic peptide near the carboxy terminus of Human IRF2BP2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IRF2BP2

Target: IRF2BP2 (Interferon Regulatory Factor 2 Binding Protein 2 (IRF2BP2))

Alternative Name: IRF2BP2

Background: IRF2BP2, like the related protein IRF2BP1, is a co-repressor that interacts specifically with the C-terminal repression domain of Interferon Regulatory Factor 2 (IRF2). IRF2BP2 is a direct target gene of p53 and is involved in cell survival during the p53 stress response, able to impede the p53-mediated transactivation of p21 and Bax. IRF2BP2 is also a co-factor of VGLL4 and is required to induce the expression of vascular endothelial growth factor A (VEGF-A) in muscle. It is normally found in the nucleus of skeletal muscle and cardiac cells, but can be found in the cytoplasm during skeletal muscle differentiation.Synonyms: IRF-2-binding protein 2, IRF-2BP2, Interferon regulatory factor 2-binding protein 2

Gene ID: 359948

NCBI Accession: NP_892017