CD73 antibody (PE)

Catalog No. ABIN1504143

This anti-CD73 antibody is a Mouse Monoclonal antibody detecting CD73 in FACS. Suitable for Human.

Quick Overview for CD73 antibody (PE) (ABIN1504143)

Target: CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD73 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: AD2

Product Details anti-CD73 Antibody (PE)

Cross-Reactivity (Details): Species reactivity (tested):Human

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS, 15 mM sodium azide, 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CD73

Target: CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Alternative Name: CD73

Background: CD73 (ecto-5´-nucleotidase) is a 70 kDa glycoprotein anchored to the extracellular leaflet of the plasma membrane by GPI. This ecto-enzyme catalyzes dephosphorylation of AMP to adenosine. CD73 is expressed in various types of cells, such as epithelial, muscle, and endothelial cells, neutrophils, lymphocytes and fibroblasts. Inflammatory mediators support CD73 expression and its enzymatic activity, leading to the release of adenosine, which modulates inflammation through adenosine receptors. CD73 is expressed in a variety of lymphomas and leukemias, including ALL and CLL, whereas immunodeficient patients usually express low levels of this protein.Synonyms: 5'-nucleotidase, NT5, NT5E, NTE

Pathways: Synaptic Membrane, Ribonucleoside Biosynthetic Process