ABCA1 antibody
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- Target See all ABCA1 Antibodies
- ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This ABCA1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Specificity
- Recognizes murine adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1). The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA1 is a member of the ABC-A sub-family, which acts as a lipid translocator. The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism. ABCA1 may play an important role in protecting against cardiovascular disease. Mutations in ABCA1 gene have been associated with Tangiers disease, a genetic disorder of lipid metabolism, and familial high density lipoprotein (HDL) deficiency.
- Purification
- Protein G purified
- Immunogen
- ABCA1 transfected HeLa cells.
- Clone
- 5A1-1422
- Isotype
- IgG2a
- Top Product
- Discover our top product ABCA1 Primary Antibody
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- Application Notes
- Approved: Flo (1:10 - 1:200), IF, WB
- Comment
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Target Species of Antibody: Mouse
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
- Alternative Name
- ABCA1 (ABCA1 Products)
- Background
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Name/Gene ID: ABCA1
Subfamily: ATP-binding cassette - ABCA/ABC1
Family: Transporter
Synonyms: ABCA1, ABC-1, ABC1, CERP, HDLDT1, Tangier disease, ATP-binding cassette 1, Td, Membrane-bound, TGD - Gene ID
- 19
- UniProt
- O95477
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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