TSC22D4 antibody (N-Term)

Catalog No. ABIN182336

The Rabbit Polyclonal anti-TSC22D4 antibody has been validated for WB and IHC. It is suitable to detect TSC22D4 in samples from Human, Rat, Guinea Pig and Dog. There are 2+ publications available.

Quick Overview for TSC22D4 antibody (N-Term) (ABIN182336)

Target: TSC22D4 (TSC22 Domain Family, Member 4 (TSC22D4))

Reactivity: Human, Rat, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSC22D4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TSC22D4 Antibody

Binding Specificity: N-Term

Sequence: SGGKKKSSFQ ITSVTTDYEG PGSPGASDPP TPQPPTGPPP RLPNGEPSPD

Predicted Reactivity: Dog: 90%, Guinea Pig: 93%, Human: 100%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against TSC22D4. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TSC22D4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 395 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TSC22D4 antibody (ABIN182336)

Canterini, Bosco, Carletti, Fuso, Curci, Mangia, Fiorenza: "Subcellular TSC22D4 localization in cerebellum granule neurons of the mouse depends on development and differentiation." in: Cerebellum (London, England), Vol. 11, Issue 1, pp. 28-40, (2012) (PubMed).

Canterini, Bosco, De Matteis, Mangia, Fiorenza: "THG-1pit moves to nucleus at the onset of cerebellar granule neurons apoptosis." in: Molecular and cellular neurosciences, Vol. 40, Issue 2, pp. 249-57, (2009) (PubMed).

Target Details for TSC22D4

Target: TSC22D4 (TSC22 Domain Family, Member 4 (TSC22D4))

Alternative Name: TSC22D4

Background: TSC22D4 is a leucine zipper-containing protein that is highly conserved during evolution. It is transcriptionally up-regulated by many different stimuli, including anti-cancer drugs and growth inhibitors. TSC22D4 may play a suppressive role in tumorigenesis.
Alias Symbols: THG1, THG-1, TILZ2
Protein Interaction Partner: NRBP2, KRT40, CCDC146, TEX11, PIH1D1, ZMYND10, APIP, NRBP1, MYLIP, ZBTB24, POLR1C, BLZF1, PRKAA2, PRKAA1, PPL, PIN1, MAD2L1, LMO2, GOLGA2, AES, BZRAP1, KEAP1, SMAD3, LBP, KPNA2, CLU, SACS, AIFM1, PRNP, PCBP1, ZNF580, SYT17, LNX1, NOC4L, ENKD1, FRMD6, LRP2
Protein Size: 395

Molecular Weight: 41 kDa

Gene ID: 81628

NCBI Accession: NM_030935, NP_112197

UniProt: Q9Y3Q8