CLIC2 antibody (C-Term)

Catalog No. ABIN183127

Product Details anti-CLIC2 Antibody

Target: CLIC2 (Chloride Intracellular Channel 2 (CLIC2))

Binding Specificity: C-Term

Reactivity: Human, Dog, Rat, Guinea Pig, Horse, Rabbit, Cow, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIC2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SAEEPPVSRR LFLDGDQLTL ADCSLLPKLN IIKVAAKKYR DFDIPAEFSG

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CLIon Channel2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLIC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 247 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CLIC2

Target: CLIC2 (Chloride Intracellular Channel 2 (CLIC2))

Alternative Name: CLIC2 (CLIC2 Products)

Background: Chloride intracellular channel 2 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. CLIon Channel 2 encodes a protein that is detected in fetal liver and adult skeletal muscle tissue. CLIon Channel2 maps to the candidate region on chromosome X for incontinentia pigmenti.
Alias Symbols: CLIC2b, XAP121
Protein Interaction Partner: UBC, FN1, NEDD4L, NEDD4, TRAPPC2,
Protein Size: 247

Molecular Weight: 27 kDa

Gene ID: 1193

NCBI Accession: NM_001289, NP_001280

UniProt: O15247

Pathways: Negative Regulation of Transporter Activity