HOXA10 antibody (N-Term)

Catalog No. ABIN184291

This Rabbit Polyclonal antibody specifically detects HOXA10 in WB and IHC. It exhibits reactivity toward Human, Mouse, Dog and Rabbitand has been mentioned in 1 publication.

Quick Overview for HOXA10 antibody (N-Term) (ABIN184291)

Target: HOXA10 (Homeobox A10 (HOXA10))

Reactivity: Human, Mouse, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HOXA10 Antibody

Binding Specificity: N-Term

Sequence: MSCSESPAAN SFLVDSLISS GRGEAGGGGG GAGGGGGGGY YAHGGVYLPP

Cross-Reactivity: Human, Mouse (Murine), Rabbit, Rat (Rattus)

Predicted Reactivity: Dog: 85%, Human: 92%, Mouse: 78%, Rabbit: 85%

Characteristics: This is a rabbit polyclonal antibody against HOXA10. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXA10

Application Details

Application Notes: WB Suggested Anti-HOXA10 Antibody Titration: 1.25 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 393 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HOXA10 antibody (ABIN184291)

Ko, Lengyel, Naora: "The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions." in: Molecular and cellular endocrinology, Vol. 317, Issue 1-2, pp. 112-9, (2010) (PubMed).

Target Details for HOXA10

Target: HOXA10 (Homeobox A10 (HOXA10))

Alternative Name: HOXA10 / HOX1H

Background: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA10 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment.
Alias Symbols: PL, HOX1, HOX1H, HOX1.8
Protein Interaction Partner: SPI1, COPS5, CREBBP, PBX1, SNAPC1, EMX1, POLR3D, SIRT2, GMNN, EP300, MEIS1, PTPN6, HOXA10, FOXO1,
Protein Size: 393

Molecular Weight: 41 kDa

Gene ID: 3206

NCBI Accession: NM_018951, NP_061824

UniProt: P31260