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TLR4 antibody

TLR4 Reactivity: Human, Monkey FACS, IHC, IP, Neut, IHC (fro) Host: Mouse Monoclonal HTA125 unconjugated
Catalog No. ABIN198155
  • Target See all TLR4 Antibodies
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Reactivity
    • 179
    • 88
    • 72
    • 37
    • 27
    • 24
    • 23
    • 18
    • 9
    • 2
    • 1
    • 1
    • 1
    Human, Monkey
    Host
    • 132
    • 69
    • 7
    • 5
    Mouse
    Clonality
    • 137
    • 76
    Monoclonal
    Conjugate
    • 95
    • 19
    • 19
    • 15
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR4 antibody is un-conjugated
    Application
    • 152
    • 125
    • 53
    • 49
    • 36
    • 28
    • 27
    • 26
    • 26
    • 25
    • 12
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Neutralization (Neut), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Reacts preferentially, especially in Flow Cytometry, with human TLR4 (CD284) that is associated with MD-2. This clone is a TLR4 (CD284) function-blocking antibody that is useful for studies on the role of TLR4 (CD284) as a receptor for LPS induced cytokine production by TLR4 bearing cells. The antibody was shown to precipitate TLR4 (100kD).
    Purification
    Purified
    Immunogen
    Human TLR4.
    Clone
    HTA125
    Isotype
    IgG2a
    Top Product
    Discover our top product TLR4 Primary Antibody
  • Application Notes
    Approved: Flo, IHC, IHC-Fr, IP, Neut

    Usage: Suitable for use in Flow Cytometry, Immunoprecipitation, and Neutralization (can be used as antagonist for TLR4, it blocks LPS-induced cytokine production). Note: Before use in biological assays, the product must be sterile-filtered and depending on the concentration to be used, dialyzed against culture medium to remove the sodium azide added.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS, 0.1 % BSA, 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Alternative Name
    TLR4 (TLR4 Products)
    Background
    Name/Gene ID: TLR4
    Family: Toll-like Receptor

    Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll
    Gene ID
    7099
    UniProt
    O00206
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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